相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Recent advances and limitations of mTOR inhibitors in the treatment of cancer
Eunus S. Ali et al.
CANCER CELL INTERNATIONAL (2022)
Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma
Firli Rahmah Primula Dewi et al.
AUTOPHAGY (2021)
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study
Jonas E. Adolph et al.
NEURO-ONCOLOGY (2021)
Systemic chemotherapy of pediatric recurrent ependymomas: results from the German HIT-REZ studies
Jonas E. Adolph et al.
JOURNAL OF NEURO-ONCOLOGY (2021)
Outcomes after first relapse of childhood intracranial ependymoma
Jessica W. Tsai et al.
PEDIATRIC BLOOD & CANCER (2021)
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Pooja Panwalkar et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Identification of key methylation differentially expressed genes in posterior fossa ependymoma based on epigenomic and transcriptome analysis
Guanyi Wang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2021)
Second series by the Italian Association of Pediatric Hematology and Oncology of children and adolescents with intracranial ependymoma: an integrated molecular and clinical characterization with a long-term follow-up
Maura Massimino et al.
NEURO-ONCOLOGY (2021)
A phase I study of sirolimus in combination with metronomic therapy (CHOAnome) in children with recurrent or refractory solid and brain tumors
Muna Qayed et al.
PEDIATRIC BLOOD & CANCER (2020)
A retrospective analysis of recurrent pediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups
Timothy A. Ritzmann et al.
PEDIATRIC BLOOD & CANCER (2020)
EPEN-54. ACNS0831, PHASE III RANDOMIZED TRIAL OF POST-RADIATION CHEMOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED EPENDYMOMA AGES 1 TO 21 YEARS
Amy Smith et al.
NEURO-ONCOLOGY (2020)
Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma
Thomas E. Merchant et al.
JOURNAL OF CLINICAL ONCOLOGY (2019)
A systematic review and meta-analysis of outcomes in pediatric, recurrent ependymoma
Lennox Byer et al.
JOURNAL OF NEURO-ONCOLOGY (2019)
Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features - a retrospective analysis of the HIT ependymoma trial cohort
Stephanie T. Juenger et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Craniospinal irradiation as part of re-irradiation for children with recurrent intracranial ependymoma
Derek S. Tsang et al.
NEURO-ONCOLOGY (2019)
A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors
Oren J. Becher et al.
PEDIATRIC BLOOD & CANCER (2017)
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome
Pooja Panwalkar et al.
ACTA NEUROPATHOLOGICA (2017)
Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis
Vijay Ramaswamy et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas
Jill Bayliss et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Re-irradiation of recurrent pediatric ependymoma: modalities and outcomes: a twenty-year survey
Maria Jesus Lobon et al.
SPRINGERPLUS (2016)
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
Kristian W. Pajtler et al.
CANCER CELL (2015)
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
S. C. Mack et al.
NATURE (2014)
PI3K Pathway Activation Provides a Novel Therapeutic Target for Pediatric Ependymoma and Is an Independent Marker of Progression-Free Survival
Hazel A. Rogers et al.
CLINICAL CANCER RESEARCH (2013)
Efficacy and safety of everolimus for subependymal giant cell astrocytomas associated with tuberous sclerosis complex (EXIST-1): a multicentre, randomised, placebo-controlled phase 3 trial
David Neal Franz et al.
LANCET (2013)
mTOR inhibitors in cancer therapy
Yekaterina Y. Zaytseva et al.
CANCER LETTERS (2012)
Survival Benefit for Pediatric Patients With Recurrent Ependymoma Treated With Reirradiation
Eric Bouffet et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)
Phosphatidylinositide-3-Kinase Inhibitors: Addressing Questions of Isoform Selectivity and Pharmacodynamic/Predictive Biomarkers in Early Clinical Trials
Paul A. Clarke et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma
Hendrik Witt et al.
CANCER CELL (2011)
mTORC1 activation in childhood ependymoma and response to sirolimus
Daniel C. Bowers et al.
JOURNAL OF NEURO-ONCOLOGY (2011)
Biomarker Development for the Clinical Activity of the mTOR Inhibitor Everolimus (RAD001): Processes, Limitations, and Further Proposals
Terence O'Reilly et al.
TRANSLATIONAL ONCOLOGY (2010)
Management strategies for recurrent ependymoma in the paediatric population
M. Sangra et al.
CHILDS NERVOUS SYSTEM (2009)
Salvage chemotherapy for metastatic and recurrent ependymoma of childhood
Eric Bouffet et al.
CHILDS NERVOUS SYSTEM (2009)
Relapsed intracranial ependymoma in children in the UK: Patterns of relapse, survival and therapeutic outcome
B. Messahel et al.
EUROPEAN JOURNAL OF CANCER (2009)
Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support
Paul A. Harris et al.
JOURNAL OF BIOMEDICAL INFORMATICS (2009)
A retrospective study of surgery and reirradiation for recurrent ependymoma
Thomas E. Merchant et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Phase I study of everolimus in pediatric patients with refractory solid tumors
Maryam Fouladi et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
DN Franz et al.
ANNALS OF NEUROLOGY (2006)
A feasibility trial of antiangiogenic (Metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer
MW Kieran et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2005)