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Cancer-Associated Thrombosis: A Taiwanese Perspective on Therapeutic Options with Focus on Non-Vitamin K Antagonist Oral Anticoagulants

期刊

ACTA CARDIOLOGICA SINICA
卷 39, 期 2, 页码 242-253

出版社

TAIWAN SOC CARDIOLOGY
DOI: 10.6515/ACS.202303_39(2).20220719A

关键词

Cancer-associated thrombosis; Deep venous thromboembolism; Evidence-based guidelines; Non-vitamin K antagonist oral anticoagulants; Pulmonary embolism

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Cancer-associated thrombosis is a common complication of malignancies. Taiwanese patients may have a lower incidence of CAT, leading to false reassurance. Oncologists and cardiologists from multiple medical institutions in Taiwan have collaborated to provide clinical consensus guidelines on the management of CAT, based on local clinical practices and international guidelines.
Cancer-associated thrombosis (CAT) is a common complication of malignancies. Patients with CAT are at risk of venous thromboembolism recurrence, but also at risk of bleeding while anticoagulated. Taiwanese patients are perceived to have a lower incidence of CAT, likely leading to false reassurance for Taiwanese patients with cancer. Because of this, oncologists and cardiologists from multiple medical institutions in Taiwan have set forth to provide clinical consensus guidelines on the management of CAT, based on local clinical practices and guided by predominant international clinical practice guidelines.This paper aims to describe the current disease burden of cancer-associated venous thromboembolism in Taiwanese cancer patients, and discusses the unmet needs and gaps in the management of this medical complication. It also outlines diagnostic and management strategies relevant to the different treatment options available, such as non -vitamin K antagonist oral anticoagulants.

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