☆ 4.7 Letter

Letter to the Editor: Innovative future concepts of extracorporeal strategies in sepsis and septic shock

CRITICAL CARE (2023)

Rationale for sequential extracorporeal therapy (SET) in sepsis

Claudio Ronco et al.

Summary: Sepsis and septic shock are still major causes of morbidity and mortality in critically ill patients. The clinical manifestation of these syndromes involves several steps, including microbial invasion, infection establishment, immune response, inflammation, tissue damage, organ dysfunction, and organ crosstalk. Different extracorporeal therapies can be used at different stages to target specific molecules or provide organ support. However, the success of these therapies may need to be evaluated using endpoints other than mortality.

CRITICAL CARE (2023)

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Article Critical Care Medicine

Clinical and biochemical endpoints and predictors of response to plasma exchange in septic shock: results from a randomized controlled trial

Klaus Stahl et al.

Summary: This study demonstrates that therapeutic plasma exchange (TPE) can rapidly improve hemodynamics and preserve stability in patients with septic shock by removing injurious mediators and replenishing protective factors. Baseline lactate concentration shows potential as a predictor for response to TPE treatment.

CRITICAL CARE (2022)

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Letter Critical Care Medicine

Cytokine adsorption in severe, refractory septic shock

Pedro David Wendel Garcia et al.

INTENSIVE CARE MEDICINE (2021)

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Article Critical Care Medicine

Effect of therapeutic plasma exchange on endothelial activation and coagulation-related parameters in septic shock

Klaus Stahl et al.

CRITICAL CARE (2020)

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Article Critical Care Medicine

Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers

Hannah Knaup et al.

CRITICAL CARE (2018)

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Letter to the Editor: Innovative future concepts of extracorporeal strategies in sepsis and septic shock

相关参考文献

Rationale for sequential extracorporeal therapy (SET) in sepsis

Clinical and biochemical endpoints and predictors of response to plasma exchange in septic shock: results from a randomized controlled trial

Cytokine adsorption in severe, refractory septic shock

Effect of therapeutic plasma exchange on endothelial activation and coagulation-related parameters in septic shock

Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers

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