相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Glial Alterations From Early to Late Stages in a Model of Alzheimer's Disease: Evidence of Autophagy Involvement in Aβ Internalization
Carlos Pomilio et al.
HIPPOCAMPUS (2016)
Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases
Yu Tang et al.
MOLECULAR NEUROBIOLOGY (2016)
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
Yaming Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Clearance systems in the brain-implications for Alzheimer disease
Jenna M. Tarasoff-Conway et al.
NATURE REVIEWS NEUROLOGY (2015)
Metallothionein-3 modulates the amyloid β endocytosis of astrocytes through its effects on actin polymerization
Sook-Jeong Lee et al.
MOLECULAR BRAIN (2015)
Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome
Mi-Hyang Cho et al.
AUTOPHAGY (2014)
Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes
Naoki Yamamoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain
Jeffrey A. Blair et al.
CURRENT ALZHEIMER RESEARCH (2014)
Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro
Sandra D. Mulder et al.
GLIA (2014)
Modulation of inflammation in transgenic models of Alzheimer's disease
Amy M. Birch et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Microglia receptors and their implications in the response to amyloid β for Alzheimer's disease pathogenesis
Deborah Doens et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Water influx into cerebrospinal fluid is significantly reduced in senile plaque bearing transgenic mice, supporting beta-amyloid clearance hypothesis of Alzheimer's disease
Hironaka Igarashi et al.
NEUROLOGICAL RESEARCH (2014)
Relationship between amyloid-beta and the ubiquitin-proteasome system in Alzheimer's disease
Liang Hong et al.
NEUROLOGICAL RESEARCH (2014)
ApoE and Aβ in Alzheimer's Disease: Accidental Encounters or Partners?
Takahisa Kanekiyo et al.
NEURON (2014)
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
Gernot Kleinberger et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
The cerebrovascular basement membrane: role in the clearance of β-amyloid and cerebral amyloid angiopathy
Alan W. J. Morris et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
The ubiquitin proteasome system in glia and its role in neurodegenerative diseases
Anne H. P. Jansen et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Extracellular chaperones prevent Aβ42-induced toxicity in rat brains
Roberta Cascella et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
The Type 2 Diabetes-Associated Gene Ide Is Required for Insulin Secretion and Suppression of α-Synuclein Levels in β-Cells
Par Steneberg et al.
DIABETES (2013)
Endothelin-converting Enzymes Degrade Intracellular β-Amyloid Produced within the Endosomal/Lysosomal Pathway and Autophagosomes
Javier Pacheco-Quinto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Amyloid-β-Induced Astrocytic Phagocytosis is Mediated by CD36, CD47 and RAGE
Raasay S. Jones et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2013)
P2Y4 Receptor-Mediated Pinocytosis Contributes to Amyloid Beta-Induced Self-Uptake by Microglia
Hui-quan Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer's Disease
Kurt M. Lucin et al.
NEURON (2013)
Low-Density Lipoprotein Receptor Related protein-1 (LRP1)-Dependent Cell Signaling Promotes Neurotrophic Activity in Embryonic Sensory Neurons
Kazuyo Yamauchi et al.
PLOS ONE (2013)
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
Philip B. Verghese et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Is There a Cerebral Lymphatic System?
Jeffrey J. Iliff et al.
STROKE (2013)
Evidence for impaired amyloid beta clearance in Alzheimer's disease
Kristin R. Wildsmith et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease
Sang-Sun Yoon et al.
BIOMOLECULES & THERAPEUTICS (2012)
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia
Hongjun Fu et al.
GLIA (2012)
Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?
Natalia N. Nalivaeva et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells
Alexander Slowik et al.
MOLECULAR NEURODEGENERATION (2012)
ApoE-Directed Therapeutics Rapidly Clear β-Amyloid and Reverse Deficits in AD Mouse Models
Paige E. Cramer et al.
SCIENCE (2012)
Proteolytic Degradation of Amyloid β-Protein
Takaomi Saido et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Microglia function in Alzheimer's disease
Egle Solito et al.
FRONTIERS IN PHARMACOLOGY (2012)
gamma-Secretase Component Presenilin Is Important for Microglia beta-Amyloid Clearance
Dorit Farfara et al.
ANNALS OF NEUROLOGY (2011)
The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis
Benedikt J. Braun et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Microglial phagocytosis induced by fibrillar β-amyloid is attenuated by oligomeric β-amyloid: implications for Alzheimer's disease
Xiao-dong Pan et al.
MOLECULAR NEURODEGENERATION (2011)
Mechanism mediating oligomeric Aβ clearance by naive primary microglia
Cheng-Ning Yang et al.
NEUROBIOLOGY OF DISEASE (2011)
Amyloid-β Peptide Is a Substrate of the Human 20S Proteasome
Xiaobei Zhao et al.
ACS CHEMICAL NEUROSCIENCE (2010)
Statins Promote the Degradation of Extracellular Amyloid β-Peptide by Microglia via Stimulation of Exosome-associated Insulin-degrading Enzyme (IDE) Secretion
Irfan Y. Tamboli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The role of microglia in amyloid clearance from the AD brain
C. Y. Daniel Lee et al.
JOURNAL OF NEURAL TRANSMISSION (2010)
Functional and physical interactions between formyl-peptide-receptors and scavenger receptor MARCO and their involvement in amyloid beta 1-42-induced signal transduction in glial cells
Lars-Ove Brandenburg et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain
Suqing Wang et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Toll-Like Receptors Expression and Signaling in Glia Cells in Neuro-Amyloidogenic Diseases: Towards Future Therapeutic Application
Dorit Trudler et al.
MEDIATORS OF INFLAMMATION (2010)
Involvement of Fc Receptors in Disorders of the Central Nervous System
Eitan Okun et al.
NEUROMOLECULAR MEDICINE (2010)
Clearance of Amyloid-beta Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimer's Disease
R. Deane et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2009)
Astrocytes are Very Sensitive to Develop Innate Immune Responses to Lipid-Carried Short Interfering RNA
Roser Gorina et al.
GLIA (2009)
Equal Numbers of Neuronal and Nonneuronal Cells Make the Human Brain an Isometrically Scaled-Up Primate Brain
Frederico A. C. Azevedo et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
CD14 and Toll-Like Receptors 2 and 4 Are Required for Fibrillar Aβ-Stimulated Microglial Activation
Erin G. Reed-Geaghan et al.
JOURNAL OF NEUROSCIENCE (2009)
Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis
Shweta Mandrekar et al.
JOURNAL OF NEUROSCIENCE (2009)
Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests
K. A. Bates et al.
MOLECULAR PSYCHIATRY (2009)
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Denise Harold et al.
NATURE GENETICS (2009)
Regional and cellular distribution patterns of insulin-degrading enzyme in the adult human brain and pituitary
Hans-Gert Bernstein et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2008)
Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes
Sabrina Utter et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid β1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease
Karine L. Richard et al.
JOURNAL OF NEUROSCIENCE (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology
R. O. Carare et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2008)
Leucine-rich glioma inactivated 3 is involved in amyloid β peptide uptake by astrocytes and endocytosis itself
Sachi Okabayashi et al.
NEUROREPORT (2008)
Involvement of formyl-peptide-receptor-like-1 and phospholipase D in the internalization and signal transduction of amyloid beta 1-42 in glial cells
L. -O. Brandenburg et al.
NEUROSCIENCE (2008)
Autophagy, amyloidogenesis and Alzheimer disease
Ralph A. Nixon
JOURNAL OF CELL SCIENCE (2007)
Effects of hypoxia and oxidative stress on expression of neprilysin in human neuroblastoma cells and rat cortical neurones and astrocytes
Lilia Fisk et al.
NEUROCHEMICAL RESEARCH (2007)
Aβ upregulates and colocalizes with LGI3 in cultured rat astrocytes
Nobuyuki Kimura et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2007)
Formyl peptide receptors on immune and nonimmune cells: Analysis of sequence conservation in FPR genes
M. A. Panaro et al.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2007)
Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease
Zhong Zhao et al.
NEUROBIOLOGY OF AGING (2007)
The TREM receptor family and signal integration
Julia Klesney-Tait et al.
NATURE IMMUNOLOGY (2006)
Role of toll-like receptor signalling in Aβ uptake and clearance
Kazuki Tahara et al.
BRAIN (2006)
Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-β peptide catabolism
Ke-Jie Yin et al.
JOURNAL OF NEUROSCIENCE (2006)
Matrix metalloproteinase-9 degrades amyloid-β fibrils in vitro and compact plaques in situ
Ping Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Nuclear factor-1-X regulates astrocyte-specific expression of the α1-antichymotrypsin and glial fibrillary acidic protein genes
SM Gopalan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Astrocyte-specific expression of the α1-antichymotrypsin and glial fibrillary acidic protein genes requires activator protein-1
SM Gopalan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CpG-containing oligodeoxynucleotide promotes microglial cell uptake of amyloid β 1-42 peptide by up-regulating the expression of the G-protein-coupled receptor mFPR2
P Iribarren et al.
FASEB JOURNAL (2005)
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
GK Gouras et al.
NEUROBIOLOGY OF AGING (2005)
Expression of scavenger receptors in glial cells -: Comparing the adhesion of astrocytes and microglia from neonatal rats to surface-bound β-amyloid
R Alarcón et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide
Y Liu et al.
BRAIN (2005)
Tissue plasminogen activator in central nervous system physiology and pathology
JP Melchor et al.
THROMBOSIS AND HAEMOSTASIS (2005)
Astroglial regulation of apolipoprotein E expression in neuronal cells - Implications for Alzheimer's disease
FM Harris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides
M Koistinaho et al.
NATURE MEDICINE (2004)
Role of oxidative modifications in atherosclerosis
R Stocker et al.
PHYSIOLOGICAL REVIEWS (2004)
Cellular distribution of the endothelin system in the human brain
V Naidoo et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2004)
Enhanced proteolysis of β-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death
MA Leissring et al.
NEURON (2003)
CD36 mediates the innate host response to β-amyloid
JB El Khoury et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Microglial apolipoprotein E and astroglial apolipoprotein J expression in vitro:: opposite effects of lipopolysaccharide
J Saura et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
RG Nagele et al.
BRAIN RESEARCH (2003)
Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain in vivo
W Farris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Blood-brain barrier damage induces release of α2-macroglobulin
L Cucullo et al.
MOLECULAR & CELLULAR PROTEOMICS (2003)
Alzheimer's disease β-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
EA Eckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
LB Yang et al.
NATURE MEDICINE (2003)
Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
J Husemann et al.
GLIA (2002)
Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
RMD Holsinger et al.
ANNALS OF NEUROLOGY (2002)
Aβ-degrading endopeptidase, neprilysin, in mouse brain:: synaptic and axonal localization inversely correlating with Aβ pathology
S Fukami et al.
NEUROSCIENCE RESEARCH (2002)
CD36, a class B scavenger receptor, is expressed on microglia in Alzheimer's disease brains and can mediate production of reactive oxygen species in response to beta-amyloid fibrils
IS Coraci et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Angiotensin-converting enzyme degrades Alzheimer amyloid β-peptide (Aβ);: Retards Aβ aggregation, deposition, fibril formation, and inhibits cytotoxicity.
JG Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Reactive astrocytes and α1-antichymotrypsin in Alzheimer's disease
CR Abraham
NEUROBIOLOGY OF AGING (2001)
Degradation of the Alzheimer's amyloid β peptide by endothelin-converting enzyme
EA Eckman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Subcellular compartment and molecular subdomain of β-amyloid precursor protein relevant to the Aβ42-promoting effects of Alzheimer mutant presenilin 2
H Iwata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
F Bard et al.
NATURE MEDICINE (2000)
Endothelin-converting enzymes and endothelin receptor B messenger RNAs are expressed in different neural cell species and these messenger rnas are coordinately induced in neurons and astrocytes respectively following nerve injury
S Nakagomi et al.
NEUROSCIENCE (2000)