期刊
EUROPEAN RADIOLOGY
卷 -, 期 -, 页码 -出版社
SPRINGER
DOI: 10.1007/s00330-023-09655-4
关键词
Magnetic resonance imaging; Diffusion weighted MRI; Multiparametric magnetic resonance imaging; Rectal cancer; Neoadjuvant chemoradiation therapy
This study aimed to determine the accuracy of three state-of-the-art MRI sequences in detecting extramural venous invasion (EMVI) in locally advanced rectal cancer patients after preoperative chemoradiotherapy. T2-weighted, DWI, and contrast-enhanced sequences were evaluated by radiologists, and the results showed that DWI was more accurate than T2-weighted and contrast-enhanced sequences for identifying EMVI following pCRT in LARC patients.
ObjectivesThe aim of this study was to determine the accuracy of three state-of-the-art MRI sequences for the detection of extramural venous invasion (EMVI) in locally advanced rectal cancer (LARC) patients after preoperative chemoradiotherapy (pCRT).MethodsThis retrospective study included 103 patients (median age 66 years old [43-84]) surgically treated with pCRT for LARC and submitted to preoperative contrast-enhanced pelvic MRI after pCRT. T2-weighted, DWI, and contrast-enhanced sequences were evaluated by two radiologists with expertise in abdominal imaging, blinded to clinical and histopathological data. Patients were scored according to the probability of EMVI presence on each sequence using a grading score ranging from 0 (no evidence of EMVI) to 4 (strong evidence of EMVI). Results from 0 to 2 were ranked as EMVI negative and from 3 to 4 as EMVI positive. ROC curves were drawn for each technique, using histopathological results as reference standard.ResultsT2-weighted, DWI, and contrast-enhanced sequences demonstrated an area under the ROC curve (AUC) respectively of 0.610 (95% CI: 0.509-0.704), 0.729 (95% CI: 0.633-0.812), and 0.624 (95% CI: 0.523-0.718). The AUC of DWI sequence was significantly higher than that of T2-weighted (p = 0.0494) and contrast-enhanced (p = 0.0315) sequences.ConclusionsDWI is more accurate than T2-weighted and contrast-enhanced sequences for the identification of EMVI following pCRT in LARC patients.
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