☆ 4.6 Review

Coronavirus disease 2019 (COVID-19) in pediatric patients with autoimmune disorders

EUROPEAN JOURNAL OF PEDIATRICS (2023)

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Article Rheumatology

Oral Antiviral Treatment for COVID-19 in Patients With Systemic Autoimmune Rheumatic Diseases

Nafsika Gerolymatou et al.

Summary: This retrospective study analyzed the use of MP and NM/R in SARD patients infected with SARS-CoV-2. The results showed favorable outcomes and acceptable safety profiles of the two oral antiviral therapies in this high-risk population. However, cases of COVID-19 rebound were identified, highlighting the need for continuous surveillance to assess the real-world efficacy and safety in subpopulations of interest.

JOURNAL OF RHEUMATOLOGY (2023)

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Article Rheumatology

Outcomes with and without outpatient SARS-CoV-2 treatment for patients with COVID-19 and systemic autoimmune rheumatic diseases: a retrospective cohort study

Grace Qian et al.

Summary: Outpatient SARS-CoV-2 treatment is associated with lower odds of severe COVID-19 outcomes in patients with systemic autoimmune rheumatic disease and COVID-19 compared with no outpatient treatment.

LANCET RHEUMATOLOGY (2023)

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Article Rheumatology

Asymptomatic SARS-CoV-2 seropositivity: patients with childhood-onset rheumatic diseases versus healthy children

Fatih Haslak et al.

Summary: This study aimed to investigate the prevalence of asymptomatic SARS-CoV-2 infection among pediatric patients with rheumatic diseases and healthy children. The results showed that children with rheumatic diseases, even those receiving immunosuppressive therapy, could be asymptomatic carriers of the virus, similar to their healthy peers.

CLINICAL RHEUMATOLOGY (2022)

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Letter Endocrinology & Metabolism

Letter to the Editor From Gregory and Moore: Age and Hospitalization Risk in People With Type 1 Diabetes and COVID-19: Data From the T1D Exchange Surveillance Study

Justin M. Gregory et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

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Article Gastroenterology & Hepatology

Inflammatory Bowel Disease Clinical Activity is Associated with COVID-19 Severity Especially in Younger Patients

Amanda Ricciuto et al.

Summary: Clinically active IBD may be a risk factor for severe COVID-19, particularly in younger patients. Controlling IBD disease, including medication compliance, and strategies to mitigate the risk of COVID-19 infection among patients with active IBD (e.g. distancing, immunization) are key to limiting adverse COVID-19 outcomes.

JOURNAL OF CROHNS & COLITIS (2022)

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Review Pediatrics

COVID-19 in children. II: Pathogenesis, disease spectrum and management

Annaleise R. Howard-Jones et al.

Summary: The global disruption of the COVID-19 pandemic has impacted every child's life in various ways, with most children experiencing mild symptoms from SARS-CoV-2 infection, but potentially facing more complex symptoms in post-infectious manifestations. Given the significant differences in clinical manifestations, treatment availability, and impacts in children compared to adults, prioritizing research specifically examining COVID-19 in children is crucial.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH (2022)

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Article Rheumatology

Seroprevalence and clinical outcomes of SARS-CoV-2 in paediatric patients with rheumatic disease

Heather M. Walters et al.

Summary: This study reports the clinical outcomes of SARS-CoV-2 infection and seroprevalence of SARS-CoV-2 IgG in immunosuppressed paediatric RD patients. Most patients with SARS-CoV-2 IgG had no symptoms of COVID-19 infection, and those with symptoms had mild symptoms, indicating a minimal risk for severe or critical COVID-19 in this patient population.

RHEUMATOLOGY (2022)

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Article Rheumatology

The clinical course of SARS-CoV-2 infection among children with rheumatic disease under biologic therapy: a retrospective and multicenter study

Betul Sozeri et al.

Summary: The study evaluated the course of COVID-19 infection in pediatric patients with rheumatic diseases receiving bDMARD treatment. The majority of patients had juvenile idiopathic arthritis. Most patients did not show worsening in the course of COVID-19 or their underlying diseases during the treatment with bDMARDs.

RHEUMATOLOGY INTERNATIONAL (2022)

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Review Rheumatology

SARS-CoV-2 Infection and COVID-19 Outcomes in Rheumatic Diseases: A Systematic Literature Review and Meta-analysis

Richard Conway et al.

Summary: This study indicates that individuals with rheumatic and musculoskeletal diseases (RMDs) have a higher risk of SARS-CoV-2 infection and an increased mortality rate compared to those without RMDs.

ARTHRITIS & RHEUMATOLOGY (2022)

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Article Pediatrics

Protective SARS-CoV-2 Antibody Response in Children With Inflammatory Bowel Disease

Luca Bosa et al.

Summary: This study aimed to evaluate the serological response to SARS-CoV-2 in children with IBD and assess the impact of COVID-19 on the clinical course of IBD. The results showed that children with IBD can mount a protective humoral response against SARS-CoV-2, and their disease course remains favorable during COVID-19 infection.

FRONTIERS IN PEDIATRICS (2022)

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Review Cell Biology

Association of HLA gene polymorphism with susceptibility, severity, and mortality of COVID-19: A systematic review

Paroma Deb et al.

Summary: HLA plays a role in COVID-19 susceptibility, severity, and mortality, but conclusive evidence is lacking due to heterogeneity in study designs and HLA typing methods. More uniformly designed, interrelated studies with global data are needed to support evidence-based medicine.

HLA (2022)

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Review Gastroenterology & Hepatology

Management of inflammatory bowel disease in the COVID-19 era

Kyeong Ok Kim et al.

Summary: During the COVID-19 pandemic, patients with inflammatory bowel disease (IBD) do not seem to have an increased risk of contracting the virus. Current medications for IBD may even have potential therapeutic benefits against COVID-19 and should be continued, except for high-dose corticosteroids. Adherence to general recommendations and special treatment for COVID-19 patients are essential during this time.

INTESTINAL RESEARCH (2022)

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Article Dermatology

Psoriasis-related treatment exposure and hospitalization or in-hospital mortality due to COVID-19 during the first and second wave of the pandemic: cohort study of 1 326 312 patients in France

L. Penso et al.

Summary: Exposure to certain treatments for psoriasis may increase the risk of hospitalization for COVID-19, but not in-hospital mortality. Systemic treatments, including biologics, do not increase the risk of in-hospital mortality for psoriasis patients during the COVID-19 pandemic.

BRITISH JOURNAL OF DERMATOLOGY (2022)

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Article Rheumatology

Clinical course and seroprevalence of COVID-19 in children with rheumatic diseases-cross-sectional study from a reference centre in Spain

Clara Udaondo et al.

Summary: This study aimed to describe the seroprevalence and clinical course of SARS-CoV-2 in a cohort of children with rheumatic diseases and assess possible risk factors. The results showed that the clinical course of COVID-19 in a cohort of Spanish pediatric patients with rheumatic diseases was mild, with more than one third of cases being asymptomatic. Higher disease activity and oral corticosteroids appeared to be risk factors for SARS-CoV-2 infection.

CLINICAL RHEUMATOLOGY (2022)

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Article Endocrinology & Metabolism

Symptoms and Glycemic Control in Young People With Type 1 Diabetes Following SARS-CoV-2 Infection: An Observational Study

Revital Nimri et al.

Summary: Young people with established type 1 diabetes experience mild COVID-19 infection, with elevated glucose levels and older age being associated with a prolonged disease course.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

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Article Rheumatology

Humoral response and safety of BNT162b2 mRNA vaccine in children with rheumatic diseases

Ozlem Akgun et al.

Summary: This study aimed to analyze the immune response and safety of the BNT162b2 mRNA vaccine in children with paediatric rheumatic diseases receiving immunomodulatory treatments. The results showed that these patients were able to mount an effective immune response after receiving two doses of the vaccine without interrupting their current treatments.

RHEUMATOLOGY (2022)

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Article Immunology

SARS-CoV-2 and Multiple Sclerosis: Potential for Disease Exacerbation

Madison MacDougall et al.

Summary: This review examines the literature regarding the potential links between SARS-CoV-2 infection and neuroimmune demyelinating diseases, such as multiple sclerosis (MS). The authors propose a hypothesis that suggests the virus enters the central nervous system through the olfactory bulb, leading to glial inflammation, damage to oligodendrocytes, and breakdown of the blood-brain barrier. This may contribute to the exacerbation of MS symptoms.

FRONTIERS IN IMMUNOLOGY (2022)

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Article Medicine, General & Internal

Is It Inflammatory Bowel Disease Flare or Pediatric Inflammatory Multisystem Syndrome Temporally Associated with COVID-19?

Paulina Krawiec et al.

Summary: This study presented four children with overlapping IBD flare and PIMS-TS/MIS-C, where IBD recognition often preceded the onset of PIMS-TS/MIS-C. These patients presented with gastrointestinal symptoms at PIMS-TS/MIS-C onset and required IVIG, ASA, and in some cases, steroids for treatment.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Medicine, General & Internal

Comparisons of Clinical Features and Outcomes of COVID-19 between Patients with Pediatric Onset Inflammatory Rheumatic Diseases and Healthy Children

Fatih Haslak et al.

Summary: This study aims to describe the clinical features and outcomes of children and late adolescents with inflammatory rheumatic diseases (IRD) and COVID-19, and comparing their severity risks with healthy children.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Dermatology

Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)

J. Zitouni et al.

Summary: This study aimed to assess the impact of COVID-19 on children with psoriasis and the severity of infection in relation to systemic treatments. The findings suggest that biologics appear to be safe in children with psoriasis and do not increase the risk of severe forms of COVID-19. Additionally, COVID-19 may lead to the development or worsening of psoriasis in children.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2022)

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Article Medicine, General & Internal

Programmed Cell Death Protein-1 Upregulation in Response to SARS-CoV-2 in Juvenile Idiopathic Arthritis: A Case-Control Study

Violetta Opoka-Winiarska et al.

Summary: This study aimed to evaluate the impact of COVID-19 disease on patients with childhood rheumatic diseases. The study found significantly higher levels of SARS-CoV-2 antibodies in JIA patients compared to the control group, and these levels were correlated with the serological response to SARS-CoV-2. Additionally, serum PD-1 levels were also significantly higher in JIA patients and control volunteers who were seropositive for SARS-CoV-2 antibodies. The findings highlight the need for further observation of these detected abnormalities.

JOURNAL OF CLINICAL MEDICINE (2022)

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Article Rheumatology

Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform

Brian MacKenna et al.

Summary: This study aimed to assess the risk of severe COVID-19 outcomes in adults with immune-mediated inflammatory diseases and on immune-modifying therapies. The findings showed that adults with immune-mediated inflammatory diseases had an increased risk of COVID-19-related death, critical care admission or death, and hospital admission compared to the general population, but most targeted immune-modifying drugs did not increase the risk of adverse COVID-19 outcomes.

LANCET RHEUMATOLOGY (2022)

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Article Public, Environmental & Occupational Health

Plasma glucose levels and diabetes are independent predictors for mortality in patients with COVID-19

Hui Long et al.

Summary: This study found that diabetes and hyperglycemia increase the risk and adverse prognosis of COVID-19 patients. Compared to non-diabetic patients, patients with diabetes are more likely to require intensive care unit treatment, experience kidney failure, and have a higher mortality rate. Hyperglycemia is associated with severe pneumonia and mortality, accompanied by changes in laboratory indicators.

EPIDEMIOLOGY AND INFECTION (2022)

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Article Dermatology

Risk of hospitalization and death due to infection in people with psoriasis: a population-based cohort study using the Clinical Practice Research Datalink

Z. Z. N. Yiu et al.

Summary: The study found that patients with psoriasis have a higher incidence rate of serious infection, as well as other infection-related risks. Further research is needed to understand how psoriasis predisposes to a higher risk of infection.

BRITISH JOURNAL OF DERMATOLOGY (2021)

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Letter Rheumatology

Absence of Severe Complications From SARS-CoV-2 Infection in Children With Rheumatic Diseases Treated With Biologic Drugs

Giovanni Filocamo et al.

JOURNAL OF RHEUMATOLOGY (2021)

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Review Rheumatology

Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis

Shintaro Akiyama et al.

Summary: Patients with autoimmune diseases have a higher risk of COVID-19, primarily due to glucocorticoid use. Monotherapy with b/tsDMARDs is associated with a lower risk of hospitalisation and death.

ANNALS OF THE RHEUMATIC DISEASES (2021)

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Letter Gastroenterology & Hepatology

The Risk of Contracting COVID-19 Is Not Increased in Patients With Celiac Disease

Jamie Zhen et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Benign Evolution of SARS-Cov2 Infections in Children With Inflammatory Bowel Disease: Results From Two International Databases

Erica J. Brenner et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Letter Endocrinology & Metabolism

Seasonal flu and COVID-19 recommendations for children, adolescents and young adults with diabetes

Andrea E. Scaramuzza et al.

DIABETIC MEDICINE (2021)

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Article Rheumatology

Clinical manifestations and outcome of SARS-CoV-2 infections in children and adolescents with rheumatic musculoskeletal diseases: data from the National Paediatric Rheumatology Database in Germany

Claudia Sengler et al.

Summary: This study investigated the clinical manifestations, course, and outcome of SARS-CoV-2 infection among children and adolescents with rheumatic and musculoskeletal diseases. The majority of patients had a mild course of infection with good outcomes, and the infection did not significantly impact the disease activity of the underlying condition in most cases.

RMD OPEN (2021)

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Review Rheumatology

The role of antirheumatics in patients with COVID-19

Christoffer B. Nissen et al.

Summary: The COVID-19 pandemic has led to over 2 million deaths worldwide, with immune modulators and immunosuppressive drugs proposed as treatments. Further studies are needed to confirm the efficacy and safety, with potential for more clarity on the use of other anti-rheumatic drugs in the next 12 months.

LANCET RHEUMATOLOGY (2021)

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Letter Endocrinology & Metabolism

Effect of COVID 19 Second Wave on Children with type 1 Diabetes Mellitus in India

Anjali Verma et al.

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS (2021)

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Review Immunology

Future perspective: biologic agents in patients with severe COVID-19

Arzu Didem Yalcin et al.

Summary: The article discusses the mechanism of cytokine storm caused by COVID-19 and proposes strategies for using monoclonal antibodies to treat severe cases, in combination with remdesivir and/or favipiravir. Additionally, it introduces some drugs targeting IL-1, IL-6, and IgE for treating the immune response related to COVID-19.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY (2021)

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Article Gastroenterology & Hepatology

Prevalence and Outcomes of COVID-19 Among Patients With Inflammatory Bowel Disease-A Danish Prospective Population-based Cohort Study

Mohamed Attauabi et al.

Summary: Patients with immune-mediated inflammatory diseases, including IBD, were less susceptible to COVID-19 compared to patients without such diseases, and use of immunosuppressive therapies or disease activity of IBD did not affect the disease course of COVID-19.

JOURNAL OF CROHNS & COLITIS (2021)

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Article Clinical Neurology

Acute disseminated encephalomyelitis in a COVID-19 pediatric patient

Adelia Maria de Miranda Henriques-Souza et al.

Summary: This case report describes a pediatric COVID-19 patient who developed acute disseminated encephalomyelitis, presenting with skin rash, headache, fever, and eventually progressing to bilateral and symmetrical motor weakness leading to respiratory failure. Follow-up imaging showed improvement in brain and spine lesions with partial clinical and neurological improvement in the patient.

NEURORADIOLOGY (2021)

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Review Rheumatology

Novel coronavirus disease-2019 (COVID-19) in people with rheumatic disease: Epidemiology and outcomes

Rebecca Grainger et al.

Summary: This review discusses the risk of infection, outcomes, and risk factors for poor outcomes in patients with rheumatic disease in the context of COVID-19. It also explores data from other immune-mediated diseases, limitations of current research efforts, translation of knowledge into practice guidance, and future research agenda.

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Prevalence of COVID-19 in Italian Children With Celiac Disease: A Cross-Sectional Study

Elena Lionetti et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Article Gastroenterology & Hepatology

Toward finding the difference between untreated celiac disease and COVID-19 infected patients in terms of CD4, CD25 (IL-2 Rα), FOXP3 and IL-6 expressions as genes affecting immune homeostasis

Nastaran Asri et al.

Summary: CD patients show higher expression levels of CD4, CD25, FOXP3, and IL-6, which may increase the risk of developing severe COVID-19 after infection with SARS-CoV-2. However, COVID-19 patients exhibit decreased expression of these genes, indicating a potential anti-inflammatory effect in CD patients. Future studies are needed to confirm the role of these genes in reducing the severity of COVID-19 in celiac patients.

BMC GASTROENTEROLOGY (2021)

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Article Endocrinology & Metabolism

Practical recommendations of the German Diabetes Society for the management of diabetes in patients with COVID-19

Stefan R. Bornstein et al.

Summary: Diabetes and cardiovascular diseases are common comorbidities in COVID-19 patients, with diabetes patients having a higher risk for severe disease progression. The exact relationship between diabetes and the clinical course of COVID-19 is not completely understood at present. The German Diabetes Association provides basic practice recommendations for treating patients with both diabetes and COVID-19.

DIABETOLOGE (2021)

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Article Clinical Neurology

COVID-19 in multiple sclerosis patients: susceptibility, severity risk factors and serological response

Ana Zabalza et al.

Summary: The study found that multiple sclerosis patients have similar incidence, risk factors, and outcomes for COVID-19 as the general population. Patients treated with anti-CD20 therapy for a longer period of time may be at a higher risk of COVID-19, and less than 20% generate an antibody response. Only age was related to severity.

EUROPEAN JOURNAL OF NEUROLOGY (2021)

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Review Immunology

SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation

Kiandokht Keyhanian et al.

Summary: Since the COVID-19 pandemic, there is increasing evidence that patients may experience neurological manifestations affecting the central and peripheral nervous systems as well as skeletal muscles. This review discusses the possible neuroimmunological mechanisms, viral triggered conditions, and therapeutic approaches for these specific complications associated with SARS-CoV-2.

JOURNAL OF NEUROIMMUNOLOGY (2021)

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Article Endocrinology & Metabolism

New onset diabetes with diabetic ketoacidosis in a child with multisystem inflammatory syndrome due to COVID-19

Monica N. Naguib et al.

Summary: This case report discusses a unique presentation of a pediatric patient with MIS-C and new-onset diabetes, highlighting the potential impact of the pandemic on the development of diabetes in children.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2021)

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Article Endocrinology & Metabolism

Children and youth with diabetes are not at increased risk for hospitalization due to COVID-19

Roque Cardona-Hernandez et al.

Summary: Data from pediatric diabetes practices in various locations demonstrate that children and adolescents with diabetes seem to have similar outcomes and prognosis to their non-diabetic peers when infected with COVID-19, with consistently milder symptoms compared to adults with diabetes.

PEDIATRIC DIABETES (2021)

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Article Mycology

First report of COVID-19-associated rhino-orbito-cerebral mucormycosis in pediatric patients with type 1 diabetes mellitus

Jyoti Diwakar et al.

Summary: The global COVID-19 pandemic has increased the risk of secondary infections, leading to COVID-19 associated mucormycosis (CAM). Two pediatric patients with asymptomatic COVID-19 infection developed ROCM during treatment and required prompt surgical intervention. Early diagnosis and aggressive treatment are crucial in managing this rapidly progressing disease.

JOURNAL DE MYCOLOGIE MEDICALE (2021)

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Review Immunology

COVID-19 in Association With Development, Course, and Treatment of Systemic Autoimmune Rheumatic Diseases

Katja Lakota et al.

Summary: Patients with autoimmune diseases are more susceptible to infections, and COVID-19 may trigger autoimmune responses, but autoantibodies following SARS-CoV-2 infection are likely transient. The risk of SARS-CoV-2 infection in patients with systemic autoimmune rheumatic diseases is slightly higher, but the course of the disease seems similar to the general population.

FRONTIERS IN IMMUNOLOGY (2021)

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Article Parasitology

One year update on the COVID-19 pandemic: Where are we now?

Sanjay Kumar Mishra et al.

Summary: The global COVID-19 pandemic has spurred scientific research to study the origin, structures, and pathogenesis of the virus, leading to the development of potential therapeutic and vaccine candidates. Despite the significant progress in understanding SARS-CoV-2 biology and therapeutics, treatment still relies heavily on supportive care. Researchers continue to work on developing effective strategies to combat the virus, with a focus on vaccine development and repurposing existing drugs.

ACTA TROPICA (2021)

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Article Dermatology

Risk of skin disorders in patients with celiac disease: A population-based cohort study

Benjamin Lebwohl et al.

Summary: There is an increased risk of multiple common skin disorders in patients with celiac disease compared to the general population, including eczema, psoriasis, urticaria, vitiligo, acne, and alopecia areata, even in the long term.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

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Letter Gastroenterology & Hepatology

Where have all the other coeliacs gone in 2020? Road for a 2021 catch-up with missed diagnoses

Francesco Valitutti et al.

Summary: The Covid-19 pandemic has put immense pressure on national health systems worldwide, leading to delays in diagnosis and treatment of various diseases, and causing a potential increase in undiagnosed and untreated cases due to fear of contracting the virus and reduced access to medical care.

DIGESTIVE AND LIVER DISEASE (2021)

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Review Infectious Diseases

Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis

Boyan K. Tsankov et al.

Summary: Children with comorbidities are at higher risk of severe COVID-19 infection and associated mortality, with a significantly increased risk compared to healthy children. Obese children also have a higher risk of COVID-19 infection.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Pediatrics

Clinical characteristics and COVID-19 outcomes in a regional cohort of pediatric patients with rheumatic diseases

Daniel Clemente et al.

Summary: This study assessed baseline characteristics and outcomes of pediatric patients with rheumatic and musculoskeletal diseases (RMD) and COVID-19, finding no differences in outcomes based on disease type. The study suggested that previous comorbidities and glucocorticoid use increased the risk of hospital admission.

PEDIATRIC RHEUMATOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Poor outcome of SARS-CoV-2 infection in patients with severe asthma on biologic therapy

Katrien Eger et al.

Summary: This study aimed to assess the incidence and disease course of COVID-19 in severe asthma patients on biologic therapy, compared to the general Dutch population. Results showed that severe asthma patients on biologic therapy had a more severe course of COVID-19, with higher rates of hospitalization, intubation, and mortality compared to the general population, potentially due to comorbidities, severity of asthmatic inflammation, use of biologics, or a combination of these factors.

RESPIRATORY MEDICINE (2021)

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Article Pediatrics

Neuroimaging manifestations in children with SARS-CoV-2 infection: a multinational, multicentre collaborative study

Camilla E. Lindan et al.

Summary: This study analyzed 38 cases of pediatric neurological diseases related to SARS-CoV-2 infection, identifying a variety of neuroimaging abnormalities. Imaging patterns included postinfectious immune-mediated acute disseminated encephalomyelitis-like changes, myelitis, and neural enhancement. Splenial lesions and myositis were observed predominantly in children with multisystem inflammatory syndrome.

LANCET CHILD & ADOLESCENT HEALTH (2021)

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Article Clinical Neurology

Outcomes of COVID-19 infection in multiple sclerosis and related conditions: One-year pandemic experience of the multicenter New York COVID-19 Neuroimmunology Consortium (NYCNIC)

Sylvia Klineova et al.

Summary: This study found that higher neurological disability and older age independently predicted hospitalization due to COVID-19. Additionally, the results demonstrate that anti-CD20 therapies significantly blunt humoral responses postinfection, a finding that carries implications with regards to natural or vaccine-mediated immunity.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2021)

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Article Endocrinology & Metabolism

Clinical characteristics and outcome of hospitalized children and adolescent patients with type 1 diabetes during the COVID-19 pandemic: data from a single center surveillance study in Egypt

Eman Monir Sherif et al.

Summary: The study found that the COVID-19 pandemic significantly impacted the prevalence and severity of diabetic ketoacidosis (DKA) among pediatric patients with type 1 diabetes, with many patients presenting late to the emergency department. Most patients were newly diagnosed and presented with DKA upon admission, while some patients showed features of COVID-19 related multi-inflammatory syndrome.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM (2021)

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Review Biochemistry & Molecular Biology

Post-acute COVID-19 syndrome

Ani Nalbandian et al.

Summary: SARS-CoV-2 is responsible for the COVID-19 pandemic, causing global healthcare crises. Recovery from COVID-19 may lead to persistent symptoms and long-term complications, prompting the need for multidisciplinary care and follow-up for survivors.

NATURE MEDICINE (2021)

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Review Genetics & Heredity

Testing at scale during the COVID-19 pandemic

Tim R. Mercer et al.

Summary: The assembly and publication of the SARS-CoV-2 genome in January 2020 allowed for immediate development of tests and led to the largest global testing programme in history. Despite efforts to control the spread, widespread community transmission of the virus has become entrenched in many countries, necessitating population-scale testing to identify and isolate infected individuals. Testing plays a crucial role in the response to the COVID-19 pandemic and is likely to continue to be vital in public health.

NATURE REVIEWS GENETICS (2021)

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Review Pediatrics

COVID-19 in childhood: Transmission, clinical presentation, complications and risk factors

Melissa K. Siebach et al.

Summary: Children account for a small percentage of global COVID-19 cases, with most cases being mild or asymptomatic, but there are rare instances of complications. Older children have a higher infection rate, while there may be a risk of vertical transmission in neonates.

PEDIATRIC PULMONOLOGY (2021)

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Article Pediatrics

Post-COVID-19 Acute Disseminated Encephalomyelitis in a 17-Month-Old

Loren A. McLendon et al.

Summary: This study reported the youngest case of postinfectious ADEM due to SARS-CoV-2 in a toddler, with full neurologic recovery after treatment. Early recognition of autoimmune and inflammatory complications is crucial for aggressive immunomodulatory treatment and improved outcomes in SARS-CoV-2 patients.

PEDIATRICS (2021)

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Article Rheumatology

COVID-19 in patients with autoimmune diseases: characteristics and outcomes in a multinational network of cohorts across three countries

Eng Hooi Tan et al.

Summary: In patients with prevalent autoimmune diseases, COVID-19 results in more complications and higher mortality rates compared to influenza, highlighting the severity of the disease.

RHEUMATOLOGY (2021)

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Article Endocrinology & Metabolism

Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes

Guy Todd Alonso et al.

Summary: Analysis of data from pediatric patients under 19 years old with type 1 diabetes and COVID-19 found that higher A1c levels were the only predictor for hospitalization, with diabetic ketoacidosis being the primary concern in this group.

JOURNAL OF DIABETES (2021)

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Article Medicine, General & Internal

Seroprevalence of Antibodies against SARS-CoV-2 in Children with Juvenile Idiopathic Arthritis a Case-Control Study

Violetta Opoka-Winiarska et al.

Summary: This study investigated the prevalence of anti-SARS-CoV-2 antibodies in children with juvenile idiopathic arthritis (JIA) and found no clear correlation between the presence of these antibodies and disease activity. Additionally, a possible link between patients' humoral immune response and disease-modifying antirheumatic treatment was identified, which requires confirmation in follow-up studies.

JOURNAL OF CLINICAL MEDICINE (2021)

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Article

COVID-19 in pediatrics: The current knowledge and practice

Esmaeil Mehraeen et al.

Infectious Disorders - Drug Targets (2021)

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Letter Gastroenterology & Hepatology

An International Reporting Registry of Patients With Celiac Disease and COVID-19: Initial Results From SECURE-CELIAC

Eugenia Uche-Anya et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2021)

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Article Medicine, General & Internal

COVID-19 and celiac disease: A pathogenetic hypothesis for a celiac outbreak

Chiara Maria Trovato et al.

Summary: Based on current literature, it is hypothesized that COVID-19 may act as a potential trigger for celiac disease in predisposed patients. Genetically predisposed individuals could have a higher likelihood of developing celiac disease following SARS-CoV-2 infection, suggesting COVID-19 as a possible cause for a future outbreak of celiac disease.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

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Article Gastroenterology & Hepatology

High Seroconversion Rate Against Severe Acute Respiratory Syndrome Coronavirus 2 in Symptomatic Pediatric Inflammatory Bowel Disease Patients

Wenly Ruan et al.

Summary: In this single-center cohort study, high rates of COVID-19 seroconversion were observed in immunosuppressed and symptomatic PIBD patients. Specifically, all symptomatic patients and 60% of asymptomatic patients seroconverted after testing positive for SARS-CoV-2. No patients required hospitalization due to COVID-19. Further research is needed to evaluate the significance of COVID-19 seroconversion.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2021)

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Article Pediatrics

Outcomes of COVID-19 in a cohort of pediatric patients with rheumatic diseases

D. Sofia Villacis-Nunez et al.

Summary: There are few reports of COVID-19 in pediatric patients with rheumatic diseases. Hospitalized patients were more likely to be African American and have cardiovascular disease, while the use of medium/high-dose corticosteroids and immunosuppressive drugs increased the risk of hospitalization. Symptoms such as fever, dyspnea, chest pain, and rash were high-risk indicators for hospitalization in this population.

PEDIATRIC RHEUMATOLOGY (2021)

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Article Clinical Neurology

Multiple sclerosis, neuromyelitis optica spectrum disorder and COVID-19: A pandemic year in Czechia

Dominika Stastna et al.

Summary: The study evaluated the incidence, severity, and risk factors of a more severe COVID-19 course among MS and NMOSD patients. Results indicated that BMI, older age, high-dose glucocorticoid treatment, and anti-CD20 therapy were associated with pneumonia in MS patients. The majority of MS patients had a mild COVID-19 course, in contrast to the more severe course experienced by NMOSD patients.

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2021)

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Article Medicine, General & Internal

Underlying Medical Conditions Associated With Severe COVID-19 Illness Among Children

Lyudmyla Kompaniyets et al.

Summary: This study investigated the risk of severe COVID-19 illness among children with underlying medical conditions and medical complexity. It found that children with type 1 diabetes, cardiac and circulatory congenital anomalies, and obesity had a higher risk of severe COVID-19 illness, highlighting the importance of close observation and cautious clinical management for these children.

JAMA NETWORK OPEN (2021)

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Article Clinical Neurology

Clinical Features of COVID-19 on Patients With Neuromyelitis Optica Spectrum Disorders

Samira Luisa Apostolos-Pereira et al.

Summary: Most NMOSD patients with COVID-19 had mild disease forms, but they had a higher likelihood of hospitalization and ICU admission compared to the general Brazilian population. While the frequency of death did not significantly differ, SARS-CoV2 infection was identified as a risk factor for NMOSD relapses. Collaboration in shared NMOSD data studies is necessary to better define factors related to COVID-19 severity and neurologic manifestations.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2021)

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Article Rheumatology

SARS-CoV-2 infection in children with rheumatic disease: Experience of a tertiary referral center

Betul Sozeri et al.

Summary: During the COVID-19 pandemic, children with rheumatic diseases have a higher rate of SARS-CoV-2 infection, but they do not appear to have an increased risk of severe COVID-19. Immunomodulatory treatments should be adjusted in case of infection, and it is not recommended to interrupt treatments in the absence of infection. Physicians should be cautious about hyperinflammatory syndrome associated with COVID-19 in rheumatic children, which could be severe and may be mistaken for primary diseases.

ARCHIVES OF RHEUMATOLOGY (2021)

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Article Pediatrics

Severe Diabetic Ketoacidosis in a Child with Type-1 Diabetes, Asthma, and COVID-19

Wilson A. Vasconez et al.

Summary: 1. The association between COVID-19 and type-1 diabetes in children is not well understood. 2. COVID-19 may exacerbate diabetic ketoacidosis and present with other complications such as leukopenia and high ferritin. 3. Clinicians should have a high index of suspicion for COVID-19 in patients with unexplainably severe diabetic ketoacidosis.

JOURNAL OF PEDIATRIC INTENSIVE CARE (2021)

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Review Endocrinology & Metabolism

COVID-19 and diabetes mellitus: from pathophysiology to clinical management

Soo Lim et al.

Summary: Initial studies have shown that patients with diabetes mellitus have a higher risk of severe COVID-19, potentially due to hyperglycaemia affecting immune and inflammatory responses. Further investigation is needed to determine the optimal management for patients with diabetes mellitus during the ongoing pandemic.

NATURE REVIEWS ENDOCRINOLOGY (2021)

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Article Clinical Neurology

The clinical spectrum and incidence of anti-MOG-associated acquired demyelinating syndromes in children and adults

C. L. de Mol et al.

MULTIPLE SCLEROSIS JOURNAL (2020)

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Letter Cell Biology

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Manli Wang et al.

CELL RESEARCH (2020)

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Article Gastroenterology & Hepatology

Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study

Lei Pan et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Cell Biology

Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes

Lihua Zhu et al.

CELL METABOLISM (2020)

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Review Biochemistry & Molecular Biology

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

Shivraj Hariram Nile et al.

CYTOKINE & GROWTH FACTOR REVIEWS (2020)

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Article Immunology

Fecal Serine Protease Profiling in Inflammatory Bowel Diseases

Amin Jablaoui et al.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)

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Letter Dermatology

Apremilast as a potential treatment option for COVID-19: No symptoms of infection in a psoriatic patient

Olga Yu Olisova et al.

DERMATOLOGIC THERAPY (2020)

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Letter Gastroenterology & Hepatology

A negative fallout of COVID-19 lockdown in Italy: Life-threatening delay in the diagnosis of celiac disease

Giulia N. Catassi et al.

DIGESTIVE AND LIVER DISEASE (2020)

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Article Gastroenterology & Hepatology

COVID-19 and immunomodulation in IBD

Markus F. Neurath

GUT (2020)

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Article Gastroenterology & Hepatology

British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic

Nicholas A. Kennedy et al.

GUT (2020)

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Letter Gastroenterology & Hepatology

Clinical and Psychological Issues in Children with Inflammatory Bowel Disease During COVID-19 Pandemic

Massimo Martinelli et al.

INFLAMMATORY BOWEL DISEASES (2020)

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Letter Dermatology

Patient-Driven Discontinuation of Dupilumab During the COVID-19 Pandemic in Two Academic Hospital Clinics at the University of Toronto

Jorge R. Georgakopoulos et al.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2020)

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Article Clinical Neurology

Multiple sclerosis and the risk of infection: considerations in the threat of the novel coronavirus, COVID-19/SARS-CoV-2

M. D. Willis et al.

JOURNAL OF NEUROLOGY (2020)

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Review Medicine, General & Internal

Childhood Rheumatic Diseases and COVID-19 Pandemic: An Intriguing Linkage and a New Horizon

Fatih Haslak et al.

BALKAN MEDICAL JOURNAL (2020)

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Letter Hematology

Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

Deepa R. J. Arachchillage et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2020)

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Article Medicine, General & Internal

Hyperinflammatory shock in children during COVID-19 pandemic

Shelley Riphagen et al.

LANCET (2020)

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Letter Medicine, General & Internal

COVID-19: consider cytokine storm syndromes and immunosuppression

Puja Mehta et al.

LANCET (2020)

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Editorial Material Gastroenterology & Hepatology

Management of IBD during the COVID-19 outbreak: resetting clinical priorities

Silvio Danese et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2020)

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Editorial Material Clinical Neurology

COVID-19 and management of neuroimmunological disorders

Hans-Peter Hartung et al.

NATURE REVIEWS NEUROLOGY (2020)

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Article Medicine, Research & Experimental

Anti-TNF containing regimens may be associated with increased risk of Clostridioides difficile infection in patients with underlying inflammatory bowel disease

Fahimeh Sadat Gholam-Mostafaei et al.

CURRENT RESEARCH IN TRANSLATIONAL MEDICINE (2020)

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Editorial Material Clinical Neurology

Neurologic manifestations in an infant with COVID-19

Rachelle Dugue et al.

NEUROLOGY (2020)

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Letter Medicine, General & Internal

Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19

Yan Zhang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Clinical Neurology

COVID-19 and MS disease-modifying therapies

Joseph R. Berger et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2020)

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Letter Clinical Neurology

Encephalitis Associated with COVID-19 Infection in an 11-Year-Old Child

Gary N. McAbee et al.

PEDIATRIC NEUROLOGY (2020)

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Article Gastroenterology & Hepatology

Association of Digestive Symptoms and Hospitalization in Patients With SARS-CoV-2 Infection

George Cholankeril et al.

AMERICAN JOURNAL OF GASTROENTEROLOGY (2020)

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Article Endocrinology & Metabolism

COVID-19 and diabetes: Insulin requirements parallel illness severity in critically unwell patients

Linda Wu et al.

CLINICAL ENDOCRINOLOGY (2020)

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Review Gastroenterology & Hepatology

Systematic Review on Inflammatory Bowel Disease Patients With Coronavirus Disease 2019: It Is Time to Take Stock

Ferdinando D'Amico et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2020)

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Article Immunology

Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Amr H. Sawalha et al.

CLINICAL IMMUNOLOGY (2020)

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Article Rheumatology

Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases

Dalifer D. Freites Nunez et al.

ANNALS OF THE RHEUMATIC DISEASES (2020)

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Article Dermatology

COVID-19 patients with psoriasis and psoriatic arthritis on biologic immunosuppressant therapy vs apremilast in North Spain

Ruben Queiro Silva et al.

DERMATOLOGIC THERAPY (2020)

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Article Cell Biology

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

Ana Campos Codo et al.

CELL METABOLISM (2020)

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Review Clinical Neurology

COVID-19: A Review for the Pediatric Neurologist

Alison Christy

JOURNAL OF CHILD NEUROLOGY (2020)

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Article Clinical Neurology

COVID-19 outcomes in MS Observational study of early experience from NYU Multiple Sclerosis Comprehensive Care Center

Erica Parrotta et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2020)

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Article Neurosciences

COVID-19 Immunopathology and the Central Nervous System: Implication for Multiple Sclerosis and Other Autoimmune Diseases with Associated Demyelination

Marina Kleopatra Boziki et al.

BRAIN SCIENCES (2020)

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Article Gastroenterology & Hepatology

Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology, and Nutrition

Dan Turner et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2020)

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Letter Dermatology

Systemic or biologic treatment in psoriasis patients does not increase the risk of a severe form of COVID-19

A. -C. Fougerousse et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2020)

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Review Clinical Neurology

Neurological associations of COVID-19

Mark A. Ellul et al.

LANCET NEUROLOGY (2020)

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Article Multidisciplinary Sciences

Factors associated with COVID-19-related death using OpenSAFELY

Elizabeth J. Williamson et al.

NATURE (2020)

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Editorial Material Anesthesiology

Corticosteroid Injections and COVID-19 Infection Risk

David C. Miller et al.

PAIN MEDICINE (2020)

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Article Endocrinology & Metabolism

COVID-19 outbreak and pediatric diabetes: Perceptions of health care professionals worldwide

Nancy Samir Elbarbary et al.

PEDIATRIC DIABETES (2020)

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Review Pediatrics

Clinical manifestations of children with COVID-19: A systematic review

Tiago H. de Souza et al.

PEDIATRIC PULMONOLOGY (2020)

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Review Clinical Neurology

Unraveling the Possible Routes of SARS-COV-2 Invasion into the Central Nervous System

Maria Lima et al.

CURRENT TREATMENT OPTIONS IN NEUROLOGY (2020)

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Article Gastroenterology & Hepatology

ESPGHAN 'biopsy-sparing' guidelines for celiac disease in children with low antitransglutaminase during COVID-19

Chiara Maria Trovato et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2020)

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Article Rheumatology

Does immunosuppressive treatment entail an additional risk for children with rheumatic diseases? A survey-based study in the era of COVID-19

Oya Koker et al.

RHEUMATOLOGY INTERNATIONAL (2020)

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Review Rheumatology

Acute respiratory viral adverse events during use of antirheumatic disease therapies: A scoping review

Adam Kilian et al.

SEMINARS IN ARTHRITIS AND RHEUMATISM (2020)

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Article Multidisciplinary Sciences

Transplacental transmission of SARS-CoV-2 infection

Alexandre J. Vivanti et al.

NATURE COMMUNICATIONS (2020)

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Review Infectious Diseases

Drugs for Multiple Sclerosis Activate Natural Killer Cells: Do They Protect Against COVID-19 Infection?

Mena Al-Ani et al.

INFECTION AND DRUG RESISTANCE (2020)

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Article Immunology

Covid-19 systemic infection exacerbates pre-existing acute disseminated encephalomyelitis (ADEM)

Omar Hussein et al.

JOURNAL OF NEUROIMMUNOLOGY (2020)

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Article Medicine, Research & Experimental

Why is SARS-CoV-2 infection more severe in obese men? The gut lymphatics - Lung axis hypothesis

Mathieu Uzzan et al.

MEDICAL HYPOTHESES (2020)

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Article Immunology

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

Miriam Merad et al.

NATURE REVIEWS IMMUNOLOGY (2020)

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Article Immunology

Recommended First-Line Antiretroviral Therapy Regimens and Risk of Diabetes Mellitus in HIV-Infected Adults in Resource-Limited Settings

Ninutcha Paengsai et al.

OPEN FORUM INFECTIOUS DISEASES (2019)

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Article Immunology

Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity

Marko Sestan et al.

IMMUNITY (2018)

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Article Dermatology

Risk of Serious Infection, Opportunistic Infection, and Herpes Zoster among Patients with Psoriasis in the United Kingdom

Junko Takeshita et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)

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Review Clinical Neurology

Comprehensive systematic review summary: Disease-modifying therapies for adults with multiple sclerosis

Alexander Rae-Grant et al.

NEUROLOGY (2018)

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Article Endocrinology & Metabolism

Glycemic Control and Risk of Infections Among People With Type 1 or Type 2 Diabetes in a Large Primary Care Cohort Study

Julia A. Critchley et al.

DIABETES CARE (2018)

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Review Pharmacology & Pharmacy

Risk of malignancies using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a systematic review and meta-analysis

Stefanos Bonovas et al.

EXPERT OPINION ON DRUG SAFETY (2016)

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Review Clinical Neurology

Disease-modifying therapies and infectious risks in multiple sclerosis

Alexander Winkelmann et al.

NATURE REVIEWS NEUROLOGY (2016)

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Article Peripheral Vascular Disease

Upregulation of circulating components of the alternative renin-angiotensin system in inflammatory bowel disease: A pilot study

Mayur Garg et al.

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM (2015)

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Article Genetics & Heredity

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Scott W. Canna et al.

NATURE GENETICS (2014)

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Review Infectious Diseases

Understanding the roles of cytokines and neutrophil activity and neutrophil apoptosis in the protective versus deleterious inflammatory response in pneumonia

Jose Bordon et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2013)

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Article Rheumatology

Infection risk in systemic lupus erythematosus patients: susceptibility factors and preventive strategies

A. Danza et al.

LUPUS (2013)

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Review Rheumatology

The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment

Joachim Listing et al.

RHEUMATOLOGY (2013)

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Article Pediatrics

Cutaneous manifestations of chikungunya fever

K. A. Seetharam et al.

INDIAN PEDIATRICS (2012)

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Review Oncology

Therapeutic potential of targeting IL-17 and IL-23 in sepsis

Markus Bosmann et al.

CLINICAL AND TRANSLATIONAL MEDICINE (2012)

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Article Dermatology

Increased risk of infectious disease requiring hospitalization among patients with psoriasis: A population-based cohort

Marlies Wakkee et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2011)

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Article Endocrinology & Metabolism

Definition, epidemiology and classification of diabetes in children and adolescents

Maria E. Craig et al.

PEDIATRIC DIABETES (2009)

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Review Immunology

TISSUE-SPECIFIC IMMUNE RESPONSES Tissue-mediated control of immunopathology in coeliac disease

Bana Jabri et al.

NATURE REVIEWS IMMUNOLOGY (2009)

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Article Immunology

CSF cytokine and chemokine profiles in acute disseminated encephalomyelitis

Takaaki Ishizu et al.

JOURNAL OF NEUROIMMUNOLOGY (2006)

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Article Multidisciplinary Sciences

Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats

T Watts et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

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Article Virology

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Martin J. Vincent et al.

VIROLOGY JOURNAL (2005)

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Article Dermatology

Family history of psoriasis, stressful life events, and recent infectious disease are risk factors for a first episode of acute guttate psoriasis: Results of a case-control study

L Naldi et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2001)

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