Chemical and cytotoxicity profiles of 11 pink pepper (Schinus spp.) samples via non-targeted hyphenated high-performance thin-layer chromatography

Review Food Science & Technology

Pink Pepper (Schinus terebinthifolius Raddi) from Extracts to application: Truths about a Fake Pepper

Adilson Roberto Locali-Pereira et al.

Summary: Bioactive compounds obtained from Schinus terebinthifolius Raddi extracts have antimicrobial and antioxidant activities and can be used as natural preservatives and flavorings. Pink pepper extracts show great market potential.

FOOD REVIEWS INTERNATIONAL (2023)

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Article Plant Sciences

Geographical variation in the chemical composition, anti-inflammatory activity of the essential oil, micromorphology and histochemistry of Schinus terebinthifolia Raddi

Janaine Alberto Marangoni et al.

Summary: This study investigated the chemical composition of the essential oil of Terphosaphis terebinthifolia collected in six states of Brazil and demonstrated its anti-inflammatory and antihyperalgesic effects. The micromorphology and histochemistry of leaves and stems provided useful information for species identification.

JOURNAL OF ETHNOPHARMACOLOGY (2023)

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Article Integrative & Complementary Medicine

HPTLC-based metabolomics approach for the detection of chokeberry (Aronia melanocarpa (Michx.) Elliott) adulteration

Stefan Ivanovic et al.

Summary: This study investigated the HPTLC profile of different chokeberry samples and identified the main markers responsible for classification using multivariate analysis. The results demonstrated that the HPTLC-based metabolomics approach is a reliable technique for detecting chokeberry adulteration.

JOURNAL OF HERBAL MEDICINE (2023)

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Article Pharmacology & Pharmacy

PPARα/γ, adiponectin, and GLUT4 overexpression induced by moronic acid methyl ester influenced glucose and triglyceride levels of experimental diabetic mice

Samuel Estrada-Soto et al.

Summary: The current study aimed to determine the antidiabetic and antidyslipidemic activities of moronic acid methyl ester. The compound demonstrated dose-dependent antidiabetic and antihyperglycemic activities, as well as reduced glucose and triglyceride levels. Increased expression of genes related to insulin sensitivity was observed, indicating a potential mechanism of action.

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2022)

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Review Biochemistry & Molecular Biology

Modern Approaches in the Discovery and Development of Plant-Based Natural Products and Their Analogues as Potential Therapeutic Agents

Asim Najmi et al.

Summary: Natural products are an important source of new lead compounds in drug discovery research, especially those derived from plants. Despite pharmaceutical companies' lack of attention to natural product drug discovery, recent technological advancements have revived scientific interest. This review provides a comprehensive overview of the various approaches used in selecting, authenticating, extracting/isolating, screening, and developing natural products, with a focus on bioactivity-guided fractionation. The integration of interdisciplinary approaches, technological advances, and new methods holds great potential for the future development of therapeutic drugs.

MOLECULES (2022)

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Article Oncology

Triterpenoids of Rhus chinensis Supressed Colorectal Cancer Progress by Enhancing Antitumor Immunity and CD8+T Cells Tumor Infiltration

Gang Wang et al.

Summary: The study demonstrated that the triterpenoid of Rhus chinensis (TER) significantly inhibited tumor growth, prolonged survival time of tumor-bearing mice, enhanced antitumor immunity, promoted the accumulation of CD8+ T cells, and regulated the expression of PD-1/PD-L1 to inhibit tumor progression, providing a potential therapeutic target for combined immunotherapy of colorectal cancer.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2022)

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Article Chemistry, Applied

Chemical, antioxidant and cytotoxic profile of hydroalcoholic extracts of plants from Southern Brazil and their activity against pathogenic fungi isolated from dogs and cats with sensitivity and resistance to conventional antifungals

Claudia Giordani et al.

Summary: This study evaluated the chemical, antioxidant, cytotoxic, and antifungal activities of hydroalcoholic extracts of native plants from Southern Brazil. The extracts showed promising antioxidant and antifungal properties, with Schinus terebinthifolia demonstrating significant inhibitory effects against some drug-resistant fungi.

NATURAL PRODUCT RESEARCH (2022)

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Article Biochemistry & Molecular Biology

Ursolic Acid Enhances the Sensitivity of MCF-7 and MDA-MB-231 Cells to Epirubicin by Modulating the Autophagy Pathway

Zhennan Wang et al.

Summary: Breast cancer is a major cause of cancer death in women worldwide, and the commonly used drug Epirubicin can lead to cardiac toxicity. Ursolic acid has been found to enhance the sensitivity of breast cancer cells to Epirubicin by modulating the autophagy pathway. This study may provide a new therapeutic strategy for combination therapy in breast cancer.

MOLECULES (2022)

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Article Chemistry, Medicinal

Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs

Jiri Hodon et al.

Summary: A set of triterpenoid pyrazines and pyridines were prepared and tested for their cytotoxicity in cancer cell lines. The results showed that the triterpenoid core determined the activity of the compounds, while the heterocycle increased the activity and modulated the specificity. Several compounds showed high cytotoxicity against leukemia cells, especially in multidrug-resistant cells. Some compounds also inhibited the growth of solid tumors. These promising compounds have potential for further development as anticancer drugs.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)

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Article Biochemistry & Molecular Biology

Moronic acid improves intestinal inflammation in mice with chronic colitis by inhibiting intestinal macrophage polarization

Shuiliang Ruan et al.

Summary: Moronic acid plays a protective role in inflammatory bowel disease (IBD) by regulating the M1 polarization of intestinal macrophages through inhibiting ROS-NF-κB-NLRP3 signaling.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022)

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Article Cell Biology

Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells

Ditte L. Fogde et al.

Summary: Ursolic acid, a naturally occurring compound, has anti-inflammatory and anti-tumor effects. This study reveals that its anti-cancer activity is achieved by targeting lysosomal function, disrupting apoptosis and autophagy pathways to kill cancer cells. Combination treatment with cationic amphiphilic drugs can enhance the anti-cancer effect of ursolic acid.

CELLS (2022)

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Review Plant Sciences

Metabolomics and Network Pharmacology in the Exploration of the Multi-Targeted Therapeutic Approach of Traditional Medicinal Plants

Bharti Sharma et al.

Summary: This review explores the role of metabolomics and network pharmacology in validating therapeutic claims and evaluating the multi-targeted therapeutic approach of traditional Indian medicinal plants. Metabolomics is an effective technique for identifying metabolites in plant matrices. Chemometric techniques are used to validate the unique characteristics and authenticity of herbal medicines. Network pharmacology is the only option for analyzing large numbers of chemicals or metabolites and validating the multi-mechanistic and therapeutic approach of herbal medicines.

PLANTS-BASEL (2022)

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Article Biochemistry & Molecular Biology

Novel Triterpenic Acid-Benzotriazole Esters Act as Pro-Apoptotic Antimelanoma Agents

Marius Mioc et al.

Summary: The synthesis and biological assessment of benzotriazole esters of pentacyclic triterpenes as potential anticancer agents were reported. These esters demonstrated dose-dependent reductions in cell viability against melanoma cells and inhibition of mitochondrial function.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

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Review Biochemistry & Molecular Biology

Betulinic acid: A natural promising anticancer drug, current situation, and future perspectives

Maniyamma Aswathy et al.

Summary: Natural products, particularly phytochemicals, have emerged as potential candidates for the development of anticancer drugs due to their structural diversities and pleiotropic effects. This article discusses betulinic acid (BA), a widely distributed natural compound, as a promising agent for the prevention and treatment of various human malignancies. The review provides insights into the mechanistic framework and key outcomes of BA in cancer suppression through modulation of multiple signaling pathways.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2022)

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Article Biochemical Research Methods

Planar bioluminescent cytotoxicity assay via genetically modified adherent human reporter cell lines, applied to authenticity screening of Saussurea costus root

Fernanda L. B. Mugge et al.

Summary: The hyphenation of high-performance thin-layer chromatography with effect-directed assays is an effective approach to detect bioactive zones and analyze multiple samples simultaneously. Recently, the combination of this separation technique with adherent human cells on the same surface has been achieved. By developing a planar bioluminescent cytotoxicity assay, the cytotoxicity of Saussurea costus root samples could be determined using genetically modified reporter cells. The assay demonstrated good performance and successfully identified the cytotoxicity of specific compounds.

JOURNAL OF CHROMATOGRAPHY A (2022)

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Review Biochemistry & Molecular Biology

Selected plant triterpenoids and their amide derivatives in cancer treatment: A review

Zulal Ozdemir et al.

Summary: This article reviews the importance and biological activity of four selected triterpenoids and their amide derivatives in cancer treatment, as well as some antimicrobial and other effects.

PHYTOCHEMISTRY (2022)

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Editorial Material Pharmacology & Pharmacy

Editorial: Metabolomics as a tool in ethnobotany-driven drug discoveries

Nokwanda Makunga et al.

FRONTIERS IN PHARMACOLOGY (2022)

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Review Immunology

Research advance of natural products in tumor immunotherapy

Jin-Ling Huo et al.

Summary: Cancer immunotherapy is a promising approach for treating tumors, but its effectiveness is limited to certain types of tumors. Natural products have been found to improve immune function by remodeling the tumor immunosuppressive microenvironment, providing an alternative method to enhance cancer immunotherapy. The discovery of new potential modulators from natural products holds great potential for guiding tumor treatment.

FRONTIERS IN IMMUNOLOGY (2022)

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Article Chemistry, Applied

GC-MS investigation and antiproliferative activities of extracts from male and female flowers of Schinus molle L.

Elisa Ovidi et al.

Summary: This study identified differences in chemical composition between male and female flowers of Schinus molle, with sesquiterpene hydrocarbons being the dominant fraction. Compounds like beta-elemene, beta-caryophyllene, and gamma-eudesmol at low concentrations showed potential synergistic cytotoxic effects on human neuroblastoma and leukemia cell lines, with leukemia cells being more sensitive to the treatment.

NATURAL PRODUCT RESEARCH (2021)

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Article Chemistry, Analytical

A bioimaging system combining human cultured reporter cells and planar chromatography to identify novel bioactive molecules

Ines Klingelhoefer et al.

Summary: This study demonstrates the novel combination of chromatographic separations with human cancer cells as biological detectors, leading to the discovery of cytotoxic substances in herbal samples and the detection of specific compounds targeting receptor-mediated signaling pathways. High-resolution mass spectrometry and fragmentation were used to further characterize the discovered compounds.

ANALYTICA CHIMICA ACTA (2021)

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Article Biochemistry & Molecular Biology

Phytochemical Profiling and Quality Control of Terminalia sericea Burch. ex DC. Using HPTLC Metabolomics

Nduvho Mulaudzi et al.

Summary: This study established a high-performance thin layer chromatography (HPTLC) chemical fingerprint for Terminalia sericea root bark to be used for quality control and analysis of chemical variation. Through analysis of over 40 samples, characteristic fingerprints containing three major bioactive compounds were identified, and chemometric analysis successfully distinguished two different chemotypes based on the chemical variation.

MOLECULES (2021)

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Review Biochemistry & Molecular Biology

Unravelling the Anticancer Mechanisms of Traditional Herbal Medicines with Metabolomics

Omolola R. Oyenihi et al.

Summary: This review explores the opportunities presented by metabolite profiling of cancer cells for anticancer drug discovery, particularly focusing on the diverse potential of Chinese, Indian, and African flora. Metabolomics may offer a holistic strategy to gain insights into the anticancer mechanisms of plants, but this area remains largely unexplored.

MOLECULES (2021)

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Article Pharmacology & Pharmacy

Is Our Natural Food Our Homeostasis? Array of a Thousand Effect-Directed Profiles of 68 Herbs and Spices

Tamara Schreiner et al.

Summary: A study investigated 68 powdered plant extracts to evaluate their bioactivity profile and identify over 60 important bioactive compounds. The hyphenation method used allowed for the detection and control of active mechanisms in traditional medicines and plant-based foods. The results demonstrated the diverse bioactivity potential of natural foods and their powerful impact on our body's homeostasis.

FRONTIERS IN PHARMACOLOGY (2021)

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Article Biochemistry & Molecular Biology

Assessment of Betulinic Acid Cytotoxicity and Mitochondrial Metabolism Impairment in a Human Melanoma Cell Line

Dorina Coricovac et al.

Summary: The study indicates that betulinic acid has significant effects on mitochondrial bioenergetics and cellular behavior in melanoma cells, inducing mitochondrial dysfunction and apoptotic cell death, making it a potential strategy for treating melanoma.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Plant Sciences

Schinus terebinthifolius fruits intake ameliorates metabolic disorders, inflammation, oxidative stress, and related vascular dysfunction, in atherogenic diet-induced obese rats. Insight of their chemical characterization using HPLC-ESI-QTOF-MS/MS

Anouar Feriani et al.

Summary: The study demonstrated that Schinus terebinthifolius fruit extract could reduce lipid accumulation, improve glycemic status, alleviate hepatic oxidative stress and inflammation, highlighting its positive anti-atherogenic effect.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

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Article Plant Sciences

Development, Validation and Application of a UHPLC-MS Method for the Quantification of Chios Mastic Gum Triterpenoids in Human Plasma #

Vincent Brieudes et al.

Summary: Chios mastic gum, the resinous secretion obtained from the barks of the shrub Pistacia lentiscus var. Chia endemic to the Greek island of Chios, has various medicinal uses, particularly for gastrointestinal disorders. Its biological properties are attributed to triterpenes, with isomasticadienonic acid and masticadienonic acid being major chemical components. However, their isolation for pharmacological studies is challenging due to structural characteristics.

PLANTA MEDICA (2021)

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Article Biochemistry & Molecular Biology

HPTLC-Based Chemical Profiling: An Approach to Monitor Plant Metabolic Expansion Caused by Fungal Endophytes

Luis F. Salome-Abarca et al.

Summary: The fungal endophytes isolated from latex bearing species showed potential to expand host plant chemical diversity. By utilizing HPTLC for metabolic profiling, the strains exhibited strong correlation between chemical profiles and colony size, indicating a role in plant defense mechanisms through biotransformation or metabolite induction. This study highlights the robustness of HPTLC-based metabolomics in monitoring interactions among fungal endophytes, host plant, and phytopathogens.

METABOLITES (2021)

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Review Biochemistry & Molecular Biology

Terpenoids' anti-cancer effects: focus on autophagy

Chirine El-Baba et al.

Summary: Terpenoids, the largest class of natural products derived mainly from plants, exhibit diverse anti-tumor effects, including anti-proliferative, apoptotic, anti-angiogenic, and anti-metastatic activities. The complex relationship between apoptosis and autophagy in cancer cells is driven by a delicate balance of protein regulation, leading to different outcomes through interrelated signaling pathways. Further research on autophagy induction by terpenoids may provide insights for novel cancer therapies and more effective treatment regimens.

APOPTOSIS (2021)

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Article Biochemical Research Methods

On-surface autosampling for liquid chromatography−mass spectrometry

Annabel Mehl et al.

JOURNAL OF CHROMATOGRAPHY A (2021)

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Article Biochemical Research Methods

Non-target bioanalytical eight-dimensional hyphenation including bioassay, heart-cut trapping, online desalting, orthogonal separations and mass spectrometry

Tamara Schreiner et al.

Summary: The challenge of identifying individual bioactive compounds in complex mixtures can be addressed by the development of an eight-dimensional hyphenation technique. This technique combines multiple separation and detection methods to efficiently analyze samples and identify bioactive compounds. The use of online analyte trapping, desalting, and multiple detection steps allows for high-throughput screening of complex samples for individual bioactive compounds.

JOURNAL OF CHROMATOGRAPHY A (2021)

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Article Chemistry, Medicinal

Proliferative Effect of Food Plant Species from Brazil's Cerrado on Cultured Fibroblasts

Fernanda L. B. Mugge et al.

Summary: The study explored the phenolic content and proliferative effects of plant extracts from the Brazilian Cerrado region on cultured fibroblasts, finding that eight extracts from six species increased cell proliferation and induced ATP production. The high phenol content in these extracts, correlated with cell proliferation induction, suggests their potential use in the cosmetic and food industries, contributing to the conservation and sustainable development of the region.

JOURNAL OF MEDICINAL FOOD (2021)

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Article Biochemistry & Molecular Biology

Analysis of the Chemical, Antioxidant, and Anti-Inflammatory Properties of Pink Pepper (Schinus molle L.)

Min Jeong Kim et al.

Summary: Pink pepper demonstrates higher antioxidant effects and contains richer phenolic substances, showing significant effects in suppressing inflammation and oxidative stress.

ANTIOXIDANTS (2021)

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Review Medicine, General & Internal

Contact Allergy Induced by Mango (Mangifera indica): A Relevant Topic?

Elena Camelia Berghea et al.

Summary: Mango allergy commonly presents as contact dermatitis, which can be localized or systemic, potentially related to sensitization to urushiol-containing plants. Patients reported from mango-cultivating countries were few, possibly due to the prevalence of other common allergenic plants in those regions. Further research is needed to understand sensitizing substances and standardize patch test reagents.

MEDICINA-LITHUANIA (2021)

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Review Food Science & Technology

Effects of structural differences on the antibacterial activity of biflavonoids from fruits of the Brazilian peppertree (Schinus terebinthifolius Raddi)

Maria Linden et al.

FOOD RESEARCH INTERNATIONAL (2020)

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Article Chemistry, Applied

Aroeira fruit (Schinus terebinthifolius Raddi) as a natural antioxidant: Chemical constituents, bioactive compounds and in vitro and in vivo antioxidant capacity

Vanessa Sales de Oliveira et al.

FOOD CHEMISTRY (2020)

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Article Food Science & Technology

Valorisation of Schinus molle fruit as a source of volatile compounds in foods as flavours and fragrances

Daniele Giuffrida et al.

FOOD RESEARCH INTERNATIONAL (2020)

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Article Agricultural Engineering

Schinus terebenthifolius Raddi extracts: From sunscreen activity toward protection of the placenta to Zika virus infection, new uses for a well-known medicinal plant

Monika B. S. Oliveira et al.

INDUSTRIAL CROPS AND PRODUCTS (2020)

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Article Biochemistry & Molecular Biology

Multidirectional insights on polysaccharides from Schinus terebinthifolius and Schinus molle fruits: Physicochemical and functional profiles, in vitro antioxidant, anti-genotoxicity, antidiabetic, and antihemolytic capacities, and in vivo anti-inflammatory and anti-nociceptive properties

Anouar Feriani et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

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Review Oncology

Predicting and Quantifying Antagonistic Effects of Natural Compounds Given with Chemotherapeutic Agents: Applications for High-Throughput Screening

G. Lavender Hackman et al.

CANCERS (2020)

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Article Chemistry, Applied

In vitro antioxidant potential and in vivo effects of Schinus terebinthifolia Raddi leaf extract in diabetic rats and determination of chemical composition by HPLC-ESI-MS/MS

Camila Cristina Iwanaga et al.

NATURAL PRODUCT RESEARCH (2019)

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Article Biochemistry & Molecular Biology

Microbiological quality, chemical profile as well as antioxidant and antidiabetic activities of Schinus terebinthifolius Raddi

Paola dos Santos da Rocha et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY (2019)

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Article Plant Sciences

Metabolic Profiling of Saponin-Rich Ophiopogon japonicus Roots Based on 1 H NMR and HPTLC Platforms 1

Yanhui Ge et al.

PLANTA MEDICA (2019)

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Article Chemistry, Analytical

Chemical Investigation of a Biologically Active Schinus molle L. Leaf Extract

Stefania Garzoli et al.

JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY (2019)

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Article Biochemistry & Molecular Biology

Chemodiversity and Antiproliferative Activity of the Essential Oil of Schinus molle Growing in Jordan

Nour H. Aboalhaija et al.

CHEMISTRY & BIODIVERSITY (2019)

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Article Biochemistry & Molecular Biology

Natural product derived privileged scaffolds in drug discovery

Emma K Davison et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2019)

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Article Engineering, Chemical

Optimization of hydrodistillation and in vitro anticancer activity of essential oil from Schinus terebinthifolius Raddi fruits

Bruno Guzzo da Silva et al.

CHEMICAL ENGINEERING COMMUNICATIONS (2019)

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Review Plant Sciences

Natural Product Triterpenoids and Their Semi-Synthetic Derivatives with Potential Anticancer Activity

Yulin Ren et al.

PLANTA MEDICA (2019)

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Letter Allergy

Pink peppercorn: A cross-reactive risk for cashew- and pistachio-allergic patients

Andrew Timothy Fong et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2019)

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Review Dermatology

Poison Ivy, Oak, and Sumac Dermatitis: What Is Known and What Is New?

Yesul Kim et al.

DERMATITIS (2019)

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Review Integrative & Complementary Medicine

Ursolic acid: An overview on its cytotoxic activities against breast and colorectal cancer cells

Eric Wei Chiang Chan et al.

JOURNAL OF INTEGRATIVE MEDICINE-JIM (2019)

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Article Toxicology

Selective in vitro anti-melanoma activity of ursolic and oleanolic acids

Camelia Oprean et al.

TOXICOLOGY MECHANISMS AND METHODS (2018)

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Article Toxicology

Selective in vitro anti-melanoma activity of ursolic and oleanolic acids

Camelia Oprean et al.

TOXICOLOGY MECHANISMS AND METHODS (2018)

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Review Biotechnology & Applied Microbiology

Natural scaffolds in anticancer therapy and precision medicine

Aloran Mazumder et al.

BIOTECHNOLOGY ADVANCES (2018)

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Article Biochemical Research Methods

Fragmentation of the main triterpene acids of apple by LC-APCI-MSn

Stefania Sut et al.

JOURNAL OF MASS SPECTROMETRY (2018)

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Article Immunology

Antibacterial activity of extracted bioactive molecules of Schinus terebinthifolius ripened fruits against some pathogenic bacteria

M. Z. M. Salem et al.

MICROBIAL PATHOGENESIS (2018)

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Article Endocrinology & Metabolism

Investigation of species and environmental effects on rhubarb roots metabolome using H-1 NMR combined with high performance thin layer chromatography

Yanhui Ge et al.

METABOLOMICS (2018)

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Article Chemistry, Medicinal

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives

Litzia Ceron-Romero et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)

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Article Chemistry, Medicinal

In vitro Cytotoxicity and Anti-herpes Simplex Virus Type 1 Activity of Hydroethanolic Extract, Fractions, and Isolated Compounds from Stem Bark of Schinus terebinthifolius Raddi

Samara Requena Nocchi et al.

PHARMACOGNOSY MAGAZINE (2016)

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Article Pharmacology & Pharmacy

From Traditional Resource to Global Commodities: - A Comparison of Rhodiola Species Using NMR Spectroscopy - Metabolomics and HPTLC

Anthony Booker et al.

FRONTIERS IN PHARMACOLOGY (2016)

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Article Biochemical Research Methods

Analysis of triterpenoids and phytosterols in vegetables by thin-layer chromatography coupled to tandem mass spectrometry

Katerina Naumoska et al.

JOURNAL OF CHROMATOGRAPHY A (2015)

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Article Biochemical Research Methods

Schinus terebinthifolius scale-up countercurrent chromatography (Part I): High performance countercurrent chromatography fractionation of triterpene acids with off-line detection using atmospheric pressure chemical ionization mass spectrometry

Mariana Neves Vieira et al.

JOURNAL OF CHROMATOGRAPHY A (2015)

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Article Plant Sciences

Anti-inflammatory effect of Schinus terebinthifolius Raddi hydroalcoholic extract on neutrophil migration in zymosan-induced arthritis

Elaine Cruz Rosas et al.

JOURNAL OF ETHNOPHARMACOLOGY (2015)

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Review Biochemistry & Molecular Biology

Triterpenes as Potentially Cytotoxic Compounds

Malwina Chudzik et al.

MOLECULES (2015)

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Article Chemistry, Medicinal

Phytochemical screening, antioxidant and antibacterial activities of extracts prepared from different tissues of Schinus terebinthifolius Raddi that occurs in the coast of Bahia, Brazil

Cinara Oliveira D'Sousa' Costa et al.

PHARMACOGNOSY MAGAZINE (2015)

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Article Genetics & Heredity

To move or to evolve: contrasting patterns of intercontinental connectivity and climatic niche evolution in Terebinthaceae (Anacardiaceae and Burseraceae)

Andrea Weeks et al.

FRONTIERS IN GENETICS (2014)

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Article Plant Sciences

Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11β-HSD 1

Juan Jose Ramirez-Espinosa et al.

PHYTOMEDICINE (2013)

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Review Multidisciplinary Sciences

Five Pistacia species (P-vera, P-atlantica, P-terebinthus, P-khinjuk, and P-lentiscus): A Review of Their Traditional Uses, Phytochemistry, and Pharmacology

Mahbubeh Bozorgi et al.

SCIENTIFIC WORLD JOURNAL (2013)

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Article Biochemical Research Methods

Analysis of dammar resin with MALDI-FT-ICR-MS and APCI-FT-ICR-MS

Signe Vahur et al.

JOURNAL OF MASS SPECTROMETRY (2012)

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Article Plant Sciences

Essential oils from Schinus terebinthifolius leaves - chemical composition and in vitro cytotoxicity evaluation

Jeferson S. Santana et al.

PHARMACEUTICAL BIOLOGY (2012)

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Article Biochemistry & Molecular Biology

α-Pinene isolated from Schinus terebintinfolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model

Alisson L. Matsuo et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

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Article Chemistry, Medicinal

In vitro cytotoxic activity of Brazilian Middle West plant extracts

Talal Suleiman Mahmoud et al.

REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY (2011)

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Article Pharmacology & Pharmacy

Inhibition of the Epstein-Barr virus lytic cycle by moronic acid

Fang-Rong Chang et al.

ANTIVIRAL RESEARCH (2010)

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Article Food Science & Technology

Chemical Composition and Anticancer and Antioxidant Activities of Schinus Molle L. and Schinus Terebinthifolius Raddi Berries Essential Oils

Houcine Bendaoud et al.

JOURNAL OF FOOD SCIENCE (2010)

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Article Plant Sciences

Cytotoxic Triterpenoids from Maytenus retusa

Sandra M. Oramas-Royo et al.

JOURNAL OF NATURAL PRODUCTS (2010)

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Article Biochemical Research Methods

Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography

Mitja Martelanc et al.

JOURNAL OF CHROMATOGRAPHY A (2009)

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Article Biochemical Research Methods

Analysis of pentacyclic triterpenes by LC-MS. A comparative study between APCI and APPI

B. Rhourri-Frih et al.

JOURNAL OF MASS SPECTROMETRY (2009)

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Article Chemistry, Applied

Chemical composition of Schinus molle essential oil and its cytotoxic activity on tumour cell lines

Cecilia Diaz et al.

NATURAL PRODUCT RESEARCH (2008)

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Article Chemistry, Medicinal

Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents

Donglei Yu et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

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Article Plant Sciences

Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum

MY Rios et al.

PLANTA MEDICA (2001)

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Chemical and cytotoxicity profiles of 11 pink pepper (Schinus spp.) samples via non-targeted hyphenated high-performance thin-layer chromatography

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