4.1 Article

A Case of Near-Fatal Bradycardia Caused by Accidental Cannabis Intoxication

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CUREUS JOURNAL OF MEDICAL SCIENCE
卷 15, 期 4, 页码 -

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CUREUS INC
DOI: 10.7759/cureus.37430

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drug-induced bradycardia; in-hospital cardiac arrest; geriatric medicine; cannabis legalization; synthetic cannabis

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The recreational and medicinal uses of cannabis are increasing worldwide. Edible formulations of cannabis have become popular, especially among the elderly, but they can be significantly more potent and have been associated with cardiovascular adverse effects. This case highlights the need for further research on the safety of oral cannabis with the increased access and popularity of edible cannabis formulations.
The recreational and medicinal uses of cannabis are increasing worldwide. Given the recent legalization of marijuana in some regions of the United States, the use of edible formulations has become increasingly popular, especially among the elderly. These new formulations can be up to 10 times more potent than previously available preparations and have been associated with a variety of cardiovascular adverse effects. Here, we present a case of an elderly male who presented with dizziness and altered mental status. He was found to be severely bradycardic and emergently required atropine. Further investigation revealed that he accidentally ingested large amounts of oral cannabis. An extensive cardiac workup revealed no other etiology for his arrhythmia. Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the most commonly studied cannabis compounds. With the increased access to and popularity of edible cannabis formulations, this case demonstrates the need for further research regarding the safety of oral cannabis.

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