4.7 Article

A Low-Cost Handheld Reconfigurable Impedimetric Readout System for Diagnostics of Viral Infections

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Business

Economic effects of the COVID-19 pandemic on entrepreneurship and small businesses

Maksim Belitski et al.

Summary: Responding to COVID-19 involves supporting small business jobs, creating productive entrepreneurship, and examining the role of financial mechanisms. The pandemic brings both challenges and opportunities for small businesses, highlighting the need for research on digitalization and financial support policies during crises.

SMALL BUSINESS ECONOMICS (2022)

Article Engineering, Biomedical

Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

Liqian Wang et al.

Summary: A self-assembled DNA-based system immobilized on a liquid-gated graphene field-effect transistor enables the electromechanical detection of ultralow levels of unamplified ions, nucleic acids, small molecules, and proteins in biofluids. This technology has been successfully applied to create an integrated and portable device for the rapid detection of SARS-CoV-2 RNA in COVID-19 patients, without the need for RNA extraction or amplification.

NATURE BIOMEDICAL ENGINEERING (2022)

Article Biophysics

Bi-ECDAQ: An electrochemical dual-immuno-biosensor accompanied by a customized bi-potentiostat for clinical detection of SARS-CoV-2 Nucleocapsid proteins

Razieh Salahandish et al.

Summary: This article introduces a multiplex electrochemical biosensor that utilizes a dual working electrode system and a customized potentiostat. It can accurately and selectively detect SARS-CoV-2 Nucleocapsid protein within 30 minutes, with low cost and high sensitivity.

BIOSENSORS & BIOELECTRONICS (2022)

Article Engineering, Electrical & Electronic

A Low-Cost Handheld Impedimetric Biosensing System for Rapid Diagnostics of SARS-CoV-2 Infections

Giancarlo Ayala-Charca et al.

Summary: This study develops a portable impedimetric biosensing system for the identification of COVID-19 patients. The system consists of a throwaway two-working electrode strip and a novel read-out circuit, providing highly reliable signal tracking and the potential for multi-biomarker detection. The system has a wide dynamic detection range and can be adapted for other infectious diseases and critical disorders.

IEEE SENSORS JOURNAL (2022)

Article Biophysics

Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing

Zehui Zhang et al.

Summary: The article introduces a new serologic assay method utilizing DNA-assisted nanopore sensing for quantification of SARS-CoV-2 antibodies in human serum. This technology provides higher accuracy, larger dynamic range, and potential for automated testing compared to current clinically used point-of-care assays and ELISA assays.

BIOSENSORS & BIOELECTRONICS (2021)

Article Multidisciplinary Sciences

Rapid electrochemical detection of coronavirus SARS-CoV-2

Thanyarat Chaibun et al.

Summary: The researchers developed an ultrasensitive electrochemical biosensor based on isothermal rolling circle amplification for rapid detection of SARS-CoV-2, capable of detecting as low as 1 copy/mu L of N and S genes in clinical samples. The sensor showed a 100% concordance with qRT-PCR results in clinical sample evaluation.

NATURE COMMUNICATIONS (2021)

Review Engineering, Electrical & Electronic

Portable Sensing Devices for Detection of COVID-19: A Review

Deniz Sadighbayan et al.

Summary: The COVID-19 pandemic has accelerated the development of portable diagnostic devices to control the spread of the virus, utilizing existing systems for detection. Various biosensors have been discussed for their adaptability in identifying viruses and other biomarkers.

IEEE SENSORS JOURNAL (2021)

Article Biophysics

Sensitive electrochemical biosensor combined with isothermal amplification for point-of-care COVID-19 tests

Hyo Eun Kim et al.

Summary: The study presents an electrochemical biosensor combined with RPA for rapid and sensitive detection of SARS-CoV-2. It allows the detection of multiple target genes, has low limits of detection, short sample-to-answer times, and can potentially serve as a point-of-care test for COVID-19 diagnosis.

BIOSENSORS & BIOELECTRONICS (2021)

Review Chemistry, Analytical

Towards Fully Integrated Portable Sensing Devices for COVID-19 and Future Global Hazards: Recent Advances, Challenges, and Prospects

Tina Shaffaf et al.

Summary: Since the onset of the COVID-19 pandemic, it has become clear that we need to be well-prepared to control the spread of infectious diseases and develop rapid diagnostic platforms. This paper focuses on protein-based assays for detecting SARS-CoV-2 and explores the potential of CMOS biosensors for implementing point-of-care testing.

MICROMACHINES (2021)

Article Medicine, General & Internal

Screen-Printed Graphene/Carbon Electrodes on Paper Substrates as Impedance Sensors for Detection of Coronavirus in Nasopharyngeal Fluid Samples

Muhammad Ali Ehsan et al.

Summary: The study introduces an impedance biosensor based on paper substrates and portable electrochemical devices for detecting the pathogen of COVID-19. By immobilizing antibodies on the electrode surface, utilizing high conductivity graphene/carbon ink, and achieving accurate identification of negative and positive COVID-19 samples.

DIAGNOSTICS (2021)

Review Biotechnology & Applied Microbiology

COVID-19 Diagnostic Strategies. Part I: Nucleic Acid-Based Technologies

Tina Shaffaf et al.

Summary: The importance of commercial diagnostic tests in early detection of infections during the pandemic has been highlighted. Tracking the progression of the virus as well as monitoring patients is essential to taking appropriate actions.

BIOENGINEERING-BASEL (2021)

Review Biotechnology & Applied Microbiology

COVID-19 Diagnostic Strategies Part II: Protein-Based Technologies

Tina Shaffaf et al.

Summary: The COVID-19 outbreak has significantly impacted human lives and highlighted the importance of developing affordable, accurate, rapid, and adaptable biosensors for early detection and large-scale screening in future pandemics.

BIOENGINEERING-BASEL (2021)

Article Engineering, Electrical & Electronic

SenSARS: A Low-Cost Portable Electrochemical System for Ultra-Sensitive, Near Real-Time, Diagnostics of SARS-CoV-2 Infections

Sammy A. Perdomo et al.

Summary: One critical step to solving the SARS-CoV-2 pandemic is to stop its spread by detecting and isolating asymptomatic individuals infected with the virus. Unfortunately, current rapid testing tools lack the ability for early detection. SenSARS is an accurate, portable, and low-cost medical device that offers real-time diagnostics and viral load tracking capabilities.

IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT (2021)

Review Chemistry, Analytical

Biosensing based on field-effect transistors (FET): Recent progress and challenges

Deniz Sadighbayan et al.

TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Emerging Telemedicine Tools for Remote COVID-19 Diagnosis, Monitoring, and Management

Heather Lukas et al.

ACS NANO (2020)

Article Chemistry, Analytical

A thumb-size electrochemical system for portable sensors

Zhen Gu et al.

ANALYST (2018)

Article Chemistry, Analytical

An embedded system for portable electrochemical detection

Sylvia Kwakye et al.

SENSORS AND ACTUATORS B-CHEMICAL (2007)