Role of Exosomes in the Invasion and Metastasis of Ovarian Cancer and Application Potential of Clinical Diagnosis and Treatment

Ovarian cancer is a highly lethal form of cancer in females, largely due to extensive metastases that often accompany the initial diagnosis. Exosomes are microvesicles size from 30 to 100nm, which can be secreted by most cells. These special extracellular vesicles play a vital role in the metastasis of ovarian cancer. In this study, we conducted a comprehensive review of current research pertaining to the role of exosomes in ovarian cancer, utilizing the PubMed (R) and Web of Science databases. Our review highlights the progress in elucidating the mechanisms by which exosomes facilitate ovarian cancer progression. Additionally, we discuss the potential of exosomes as a novel therapeutic target for ovarian cancer treatment. Overall, our review provides valuable insights into the current state of research on exosomes in ovarian cancer therapy.

Automated summary

Ovarian cancer is a highly lethal form of cancer in females, mainly due to extensive metastases. Exosomes, microvesicles secreted by most cells, play a vital role in the metastasis of ovarian cancer. This study conducted a comprehensive review of current research on the role of exosomes in ovarian cancer, highlighting the progress in elucidating the mechanisms of their involvement. It also discusses the potential of exosomes as a novel therapeutic target for ovarian cancer treatment.