Very early onset of coronary artery aneurysm in a 3-month infant with Kawasaki disease: a case report and literature review

BackgroundKawasaki disease (KD) is a medium vessel vasculitis, of unknown etiology, typically presenting in children younger than 5 years of age. Prolonged fever (at least five days) is a major clinical criterion of KD, while cardiac involvement may occur in up to 25% of patients, generally in the second week of the disease.Case presentationWe describe the case of KD developing in a 3-month infant, with an early occurrence of coronary artery aneurysm after only 3 days of fever, complicated by thrombosis, requiring aggressive treatments.ConclusionsTime of development of cardiac complications can be different in young infants with KD and both diagnostic criteria and treatment indications should be individualized in this class of age.

Automated summary

This case report describes a 3-month infant with Kawasaki disease who developed coronary artery aneurysm and thrombosis after only 3 days of fever, highlighting the importance of individualized diagnostic criteria and treatment indications in young infants with KD.