4.6 Article

Annulation of α-bromocinnamaldehydes to access 3-formyl-imidazo[1,2-α]pyridines and pyrimidines under transition metal-free conditions

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Organic

Construction of a Pyrimidine Framework through [3+2+1] Annulation of Amidines, Ketones, and N,N-Dimethylaminoethanol as One Carbon Donor

Zemin Qin et al.

Summary: An efficient and eco-friendly synthesis method for pyrimidine derivatives has been developed, involving a three-component annulation. This method forms one C-C and two C-N bonds through the C(sp(3))-H activation of N,N-Dimethylaminoethanol as the carbon donor. The reaction shows good tolerance to various functional groups in air, making it a highly versatile alternative for constructing pyrimidine frameworks.

JOURNAL OF ORGANIC CHEMISTRY (2021)

Article Chemistry, Organic

Simple inorganic base promoted C-N and C-C formation: synthesis of benzo[4,5]imidazo[1,2-a]pyridines as functional AIEgens used for detecting picric acid

Kai Yang et al.

Summary: Metal-free catalyzed intermolecular tandem Michael addition/cyclization has been developed for the synthesis of benzo[4,5]imidazo[1,2-a]pyridines, showing good yields and functional group tolerance. The newly synthesized compounds exhibit excellent solid-state fluorescence as aggregation-induced emission luminogens (AIEgens), with some products capable of detecting nitroaromatic explosives like picric acid.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

Article Chemistry, Medicinal

Design, synthesis and antibacterial evaluation of 2,4-disubstituted-6-thiophenyl-pyrimidines

Zhiyuan Fang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)

Article Chemistry, Organic

Copper- catalyzed three- component synthesis of pyrimidines from amidines and alcohols

Tianchao Shi et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

A Four-Component Reaction Strategy for Pyrimidine Carboxamide Synthesis

Wei Guo et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Organic

Base-Mediated Three-Component Tandem Reactions for the Synthesis of Multisubstituted Pyrimidines

Dongqing Liu et al.

JOURNAL OF ORGANIC CHEMISTRY (2017)

Article Chemistry, Physical

Au(I)-catalyzed domino intramolecular cyclization for the synthesis of 2,4-disubstituted pyrimidines

Haiying Zhan et al.

CATALYSIS COMMUNICATIONS (2016)

Article Chemistry, Multidisciplinary

Synthesis of imidazo[1,2-a]pyridines: a decade update

Avik Kumar Bagdi et al.

CHEMICAL COMMUNICATIONS (2015)

Article Chemistry, Multidisciplinary

Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C-H bonds with DMSO using molecular oxygen

Hua Cao et al.

CHEMICAL COMMUNICATIONS (2015)

Article Chemistry, Multidisciplinary

A Sustainable Multicomponent Pyrimidine Synthesis

Nicklas Deibl et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Chemistry, Organic

General and Rapid Pyrimidine Condensation by Addressing the Rate Limiting Aromatization

Daniel R. Fandrick et al.

ORGANIC LETTERS (2014)

Article Chemistry, Multidisciplinary

Copper-Catalyzed Intramolecular Dehydrogenative Aminooxygenation: Direct Access to Formyl-Substituted Aromatic N-Heterocycles

Honggen Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Article Chemistry, Medicinal

Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase

Richard Ducray et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)

Article Chemistry, Medicinal

Advent of Imidazo[1,2-a]pyridine-3-carboxamides with Potent Multi- and Extended Drug Resistant Antituberculosis Activity

Garrett C. Moraski et al.

ACS MEDICINAL CHEMISTRY LETTERS (2011)

Review Plant Sciences

The role of natural product chemistry in drug discovery

MS Butler

JOURNAL OF NATURAL PRODUCTS (2004)