Development of a fully automated continuous, integrated production system for all reaction processes of ibuprofen

We developed a continuous, integrated production system for all reaction processes targeting ibuprofen. We succeeded in obtaining pure ibuprofen at 38% for all steps, and a production efficiency of 47 mg h(-1).

Automated summary

We developed a continuous, integrated production system that achieved a production efficiency of 47 mg h(-1) for pure ibuprofen at 38% yield across all reaction processes.