4.6 Article

Site-selective radiolabeling using mushroom tyrosinase and the strain-promoted oxidation-controlled 1,2-quinone cycloaddition

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemical Research Methods

Modification of Cysteine-Substituted Antibodies Using Enzymatic Oxidative Coupling Reactions

Wendy Cao et al.

Summary: Cysteines are commonly used as handles to synthesize antibody-drug conjugates, and tyrosinase can be used to attach phenolic cargo to cysteines engineered on antibody surfaces. This method provides more stable linkages and can be used for constructing antibody conjugates with cytotoxic payloads and attaching various cargos.

BIOCONJUGATE CHEMISTRY (2023)

Article Oncology

Monoclonal antibody based radiopharmaceuticals for imaging and therapy

Mai Lin et al.

Summary: The concept of personalized medicine has been steadily growing, with monoclonal antibodies playing a crucial role in cancer therapy, offering both opportunities and limitations that are becoming increasingly defined.

CURRENT PROBLEMS IN CANCER (2021)

Article Biochemical Research Methods

Non-Genetic Generation of Antibody Conjugates Based on Chemoenzymatic Tyrosine Click Chemistry

Jorick J. Bruins et al.

Summary: This study presents a general approach for conjugating human IgG1 antibodies with cytotoxic drugs, validated by efficient and clean generation of potent antibody-drug conjugates and their in vitro evaluation.

BIOCONJUGATE CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Tyrosinase-Mediated Oxidative Coupling of Tyrosine Tags on Peptides and Proteins

Alan M. Marmelstein et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Radiology, Nuclear Medicine & Medical Imaging

The Impact of FcγRI Binding on Immuno-PET

Delphine Vivier et al.

JOURNAL OF NUCLEAR MEDICINE (2019)

Article Biochemistry & Molecular Biology

Rapid screening of IgG quality attributes - effects on Fc receptor binding

Karin P. M. Geuijen et al.

FEBS OPEN BIO (2017)

Review Radiology, Nuclear Medicine & Medical Imaging

Site-Specifically Labeled Immunoconjugates for Molecular Imaging-Part 2: Peptide Tags and Unnatural Amino Acids

Pierre Adumeau et al.

MOLECULAR IMAGING AND BIOLOGY (2016)

Review Radiology, Nuclear Medicine & Medical Imaging

Site-Specifically Labeled Immunoconjugates for Molecular Imaging-Part 1: Cysteine Residues and Glycans

Pierre Adumeau et al.

MOLECULAR IMAGING AND BIOLOGY (2016)

Article Biochemistry & Molecular Biology

The Structural Role of Antibody N-Glycosylation in Receptor Interactions

Ganesh P. Subedi et al.

STRUCTURE (2015)

Article Biotechnology & Applied Microbiology

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Ben-Quan Shen et al.

NATURE BIOTECHNOLOGY (2012)

Article Biochemistry & Molecular Biology

Recognition of IgG by Fcγ receptor -: The role of Fc glycosylation and the binding of peptide inhibitors

S Radaev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)