☆ 4.8 Article

Enantioselective total syntheses of six natural and two proposed meroterpenoids from Psoralea corylifolia

CHEMICAL SCIENCE (2023)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Integrative & Complementary Medicine

Psoralea corylifoliaL.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics

Lele Chen et al.

Summary: Psoralea corylifolia L., also known as Bu-gu-zhi in Chinese, has been valued for its medicinal properties since ancient times. This paper provides a comprehensive overview of the botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control, and pharmacokinetics of Psoralea corylifolia L. It also highlights the potential future research directions.

CHINESE MEDICINE (2023)

添加到收藏夹

Article Chemistry, Organic

Tandem Oxidative Ritter Reaction/Hydration/Aldol Condensation of α-Arylketones with Propiolonitriles for the Construction of 3-Acyl-3-pyrrolin-2-ones

Meng-En Chen et al.

Summary: A novel tandem oxidative Ritter reaction/hydration/aldol condensation has been developed for the synthesis of functionalized 3-acyl-3-pyrrolin-2-ones. This protocol involves the efficient construction of four chemical bonds and the formation of a ring bearing an aza-quaternary center, achieved by introducing functionalized nitriles.

JOURNAL OF ORGANIC CHEMISTRY (2023)

添加到收藏夹

Article Chemistry, Multidisciplinary

Divergent Total Syntheses of (-)-Crinipellins Facilitated by a HAT-Initiated Dowd-Beckwith Rearrangement

Yifan Zhao et al.

Summary: A new method has been developed for the efficient assembly of diversely functionalized polyquinane frameworks, leading to asymmetric total syntheses of various tetraquinane natural products in a concise and divergent manner.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Review Chemistry, Organic

Electrocatalysis as a key strategy for the total synthesis of natural products

Mintu Munda et al.

Summary: Electrochemical strategies are becoming an important method for the synthesis of organic compounds, particularly in the synthesis of heterocyclic motifs, enabling a wide range of nonclassical bond disconnections. Anodic electrochemical oxidative strategies have been successfully utilized in the synthesis of various structurally intriguing natural products.

ORGANIC & BIOMOLECULAR CHEMISTRY (2022)

添加到收藏夹

Article Plant Sciences

Psoralea corylifolia L.: Panacea to several maladies

Neha Mahajan et al.

Summary: Psoralea corylifolia is a medicinal plant used in traditional herbal medicine for treating various skin disorders. It contains numerous bioactive compounds with anti-vitiligo, anti-microbial, anti-tumor, and anti-depression properties. Further research is needed to explore the extraction methods and dosage optimization of its bioactive constituents.

SOUTH AFRICAN JOURNAL OF BOTANY (2022)

添加到收藏夹

Editorial Material Multidisciplinary Sciences

Overcoming antibiotic resistance through efficient and scalable total synthesis

Yang Jiao et al.

NATIONAL SCIENCE REVIEW (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Exploration of Oxidative Ritter-Type Reaction of α-Arylketones and Its Application for the Collective Total Syntheses of Erythrina Alkaloids

Meng-En Chen et al.

Summary: In this article, we report the development of an oxidative Ritter-type reaction for the efficient synthesis of sterically hindered N-acyl aza-quaternary carbon structures. The reaction demonstrates a broad substrate scope, short reaction time, and mild reaction conditions, addressing the issues of the classical Ritter reaction. Through this new reaction strategy, the total synthesis of erythrina alkaloids has been successfully achieved.

CCS CHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Merging Carbonyl Addition with Photocatalysis

Huan-Ming Huang et al.

Summary: The carbonyl group plays an important role in chemical reactions, and its combination with radicals through photoredox catalysis can lead to unique transformations. A novel strategy of using simple carbonyl compounds as intermolecular radical acceptors enables carbon-carbon and carbon-heteroatom disconnections. These reactions do not require metals, ligands, or additives, offering high atom economy. The combination of photoredox and metal catalysis has also been utilized to achieve notable transformations.

ACCOUNTS OF CHEMICAL RESEARCH (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis

Spencer P. Pitre et al.

Summary: Recent progress in visible light photocatalytic reactions has revitalized the use of photochemistry in the synthesis of complex organic molecules. This review examines total syntheses published by the end of 2020 that employ visible-light photoredox catalysis, providing insights on functional group compatibility and synthetic strategies.

CHEMICAL REVIEWS (2022)

添加到收藏夹

Review Chemistry, Applied

Recent Progress in Solid-Phase Total Synthesis of Naturally Occurring Small Peptides

Hong Yan et al.

Summary: This review highlights the recent progress in solid-phase total synthesis of naturally occurring small peptides from 2014 to July 2021, which not only aids in the identification of peptide structures and synthesis of analogues, but also simplifies the isolation of intermediates.

ADVANCED SYNTHESIS & CATALYSIS (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Catalytic Enantioselective Pictet-Spengler Reaction of α-Ketoamides Catalyzed by a Single H-Bond Donor Organocatalyst

Remi Andres et al.

Summary: This paper reports the first examples of catalytic enantioselective PSR of tryptamines with alpha-ketoamides, and a new class of easily accessible organocatalysts was developed to achieve excellent yields and enantioselectivities.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Bioactive terpenoids derived from plant endophytic fungi: An updated review (2011-2020)

Bahman Zamani Amirzakariya et al.

Summary: Plant endophytes are important sources of bioactive compounds, particularly terpenoids. This review summarizes the newly isolated terpenoids from plant endophytic fungi and their biological activities from 2011 to 2020.

PHYTOCHEMISTRY (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Deconstructive Synthesis of Bridged and Fused Rings via Transition- Metal-Catalyzed Cut-and-Sew Reactions of Benzocyclobutenones and Cyclobutanones

Yibin Xue et al.

ACCOUNTS OF CHEMICAL RESEARCH (2022)

添加到收藏夹

Review Chemistry, Organic

Diversity-Oriented Synthesis and Chemoinformatics: A Fruitful Synergy towards Better Chemical Libraries

Elena Lenci et al.

Summary: In the past two decades, Diversity-Oriented Synthesis (DOS) has undergone significant changes, shifting from a focus on structural diversity to incorporating new approaches to enhance the biological outcomes of molecules. Chemoinformatics has played a crucial role in identifying unexplored biologically-relevant regions of chemical space and visualizing and predicting the structural diversity and complexity of compounds within DOS libraries.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Divergent Total Syntheses of Napelline-Type C20-Diterpenoid Alkaloids: (-)-Napelline, (+)-Dehydronapelline, (-)-Songorine, (-)-Songoramine, (-)-Acoapetaldine D, and (-)-Liangshanone

Shicheng Jin et al.

Summary: The study presents a new method for the synthesis of napelline-type alkaloids, achieving the construction of the core structure and characteristic chemical groups through a series of reactions, including conjugate addition and cyclization.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Concise Chemoenzymatic Synthesis of Gedunin

Jian Li et al.

Summary: Limonoids have been the focus of synthetic community due to their complex structures and potential medicinal applications. This study presents the first de novo synthesis of gedunin, a ring D-seco limonoid with HSP90 inhibitory activity, in 13 steps. The strategy used in this study may open up possibilities for the synthesis of a wider range of oxidized limonoids.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Enantioselective Total Synthesis of (+)-Aberrarone

Willi M. Amberg et al.

Summary: This study presents the total synthesis of the complex molecule (+)-aberrarone using an Au-catalyzed-Sn-mediated cascade reaction, which efficiently closes four rings in the molecule. The method offers a stereoselective approach to synthesizing the natural product with a unique tetracyclic skeleton.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Total Synthesis of (-)-Principinol C

Tianhao Ma et al.

Summary: We have achieved the first total synthesis of (-)-principinol C, which is a natural product with an intriguing and complex 5/7/6/5 tetracyclic skeleton and eight contiguous stereocenters. The key step in assembling the 5/7/6/5 tetracyclic skeleton was the intramolecular Pauson-Khand reaction. This synthetic route represents the first application of intramolecular Pauson-Khand reaction of enyne to construct the 7,5-bicyclic ring system in natural product synthesis.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Syntheses of Bufospirostenin A and Ophiopogonol A by a Conformation-Controlled Transannular Prins Cyclization

Peicheng Yang et al.

Summary: This study reports a method for precise control of the conformation of cyclodecenones under non-Curtin-Hammett conditions, enabling the first cis-selective transannular Prins cyclization. The concise syntheses of the target compounds were achieved in only seven steps from inexpensive starting materials.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Multidisciplinary

Unified Total Syntheses of Benzenoid Cephalotane-Type Norditerpenoids: Cephanolides and Ceforalides

Goh Sennari et al.

Summary: Guided by chemical network analysis, the synthetic studies towards C18- and C19-benzenoid cephalotane-type norditerpenoids were carried out, leading to the construction of core structure in a concise manner and improvement of efficiency through reaction optimization.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2022)

添加到收藏夹

Article Chemistry, Organic

Solid-Phase-Based Synthesis of Lactazole-Like Thiopeptides

Yue Zhang et al.

Summary: This article presents a strategy for synthesizing novel lactazole-like thiopeptides, including the preparation of central triheterocyclic amino acid and its use in solid-phase peptide synthesis, as well as a technique for preparing C-terminally functionalized thiopeptides for biological studies. The synthesis of 11 TNIK-inhibitor thiopeptides and 6 derivatives highlights the practicality of the developed protocols.

ORGANIC LETTERS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Ketones as strategic building blocks for the synthesis of natural product-inspired compounds

Daniel J. Foley et al.

Summary: Natural product-inspired compound collections are important sources for discovering new bioactive compounds for treating diseases. Ketones, with their variety of synthetic transformations, prevalence as commercial building blocks, and relative ease of synthesis, can be valuable as starting materials for the synthesis of natural product-inspired compounds. This review explores the use of ketones as general precursors and summarizes the synthetic transformations available for the annulation of natural product ring-systems to ketone starting materials.

CHEMICAL SOCIETY REVIEWS (2022)

添加到收藏夹

Review Biochemistry & Molecular Biology

Chemoenzymatic approaches to plant natural product inspired compounds

Rebecca Roddan et al.

Summary: This review highlights recent chemoenzymatic syntheses towards plant natural products and analogues, focusing on the advantages of incorporating biocatalysts into a synthetic strategy.

NATURAL PRODUCT REPORTS (2022)

添加到收藏夹

Review Chemistry, Multidisciplinary

Navigating the Pauson-Khand Reaction in Total Syntheses of Complex Natural Products

Zhen Yang

Summary: The total synthesis endeavors contribute to the discovery and invention of new synthetic reactions to advance organic synthesis. Bioactive compounds share common features, such as molecular complexity, protein-binding ability, structural rigidity, and three-dimensionality. Total synthesis offers an alternative solution for generating scarce natural products and their derivatives for studying their biological functions.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

添加到收藏夹

Article Chemistry, Physical

Carbonyl Desaturation: Where Does Catalysis Stand?

Samer Gnaim et al.

Summary: The article discusses the strong parallel between simple alcohol oxidation and carbonyl desaturation, highlighting recent advances in carbonyl desaturation over the past 5 years using both transition-metal-catalyzed and metal-free approaches. Through historical overview and detailed examination of new developments, the ideal context for a catalytic strategy to emerge is explored.

ACS CATALYSIS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Bidirectional Total Synthesis of Phainanoid A via Strategic Use of Ketones

Jiaxin Xie et al.

Summary: The total synthesis of phainanoid A was achieved using a bidirectional synthetic strategy, which featured two highly diastereoselective transformations mediated by transition metals. The strategic use of ketones in key transformations allowed for rapid growth of molecular complexity, paving the way for efficient preparations of complex and biologically significant DTTs.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Asymmetric Total Synthesis of Taxol

Ya-Jian Hu et al.

Summary: Taxol is a famous natural diterpenoid and important anticancer medicine with synthetic challenges. This study presents an asymmetric total synthesis of Taxol through a concise approach and the efficient construction of the challenging eight-membered ring. The new convergent approach allows for the creation of Taxol derivatives for further biological research.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Review Chemistry, Medicinal

Diacylglycerol acyltransferase inhibitory new meroterpenes from the seeds of Psoralea corylifolia, and their structure-activity relationship study

Meng-Xue Xiu et al.

Summary: Five new meroterpenes were isolated from Psoralea corylifolia seeds, along with six known compounds. The compounds showed selective inhibitory activity against DGAT1, with IC50 values ranging from 61.5 to 89.1 μM.

FITOTERAPIA (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Carbonyl 1,2-transposition through triflate-mediated α-amination

Zhao Wu et al.

Summary: In this study, a simple protocol was described to transposes a ketone to an adjacent carbon atom. By utilizing a series of reactions, this method allows for the rapid access to unusual bioactive analogs through late-stage functionalization of intermediates.

SCIENCE (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Modular Chemical Synthesis of Streptogramin and Lankacidin Antibiotics

Lingchao Cai et al.

Summary: The rapid development of antimicrobial resistance has become a global health crisis, requiring decisive action. This article summarizes efforts to develop streptogramin and lankacidin antibiotics that overcome bacterial resistance through modular chemical synthesis, demonstrating that rational design and chemical synthesis can revitalize classes of antibiotics limited by naturally arising resistance mechanisms.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Asymmetric Total Synthesis of Norzoanthamine

Zhengyuan Xin et al.

Summary: The asymmetric total synthesis of norzoanthamine was achieved using radical reactions as key steps. This approach allowed for precise control of stereochemistry and construction of the highly congested heptacyclic skeleton, addressing a major synthetic challenge in most zoanthamine alkaloids.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Catalytic Generation of Carbanions through Carbonyl Umpolung

Shun Wang et al.

Summary: The article summarizes recent progress in the generation of alkyl carbanions through catalytic carbonyl Umpolung, discussing two different catalytic approaches and their reaction scope, mechanistic insights, synthetic applications, and potential future developments.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Integrative & Complementary Medicine

New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production

Qingxia Xu et al.

Summary: This study isolated various novel bakuchiol derivatives from Psoralea corylifolia L., some of which showed anti-inflammatory activities. Structure-activity relationship analysis suggested that uncyclized compounds with oxygen substitution at specific sites exhibit strong inhibitory effects.

CHINESE MEDICINE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Desymmetrization of 1,3-Diones by Catalytic Enantioselective Condensation with Hydrazine

Binmiao Yang et al.

Summary: This method achieves an unprecedented desymmetrization of meso 1,3-diones by enantioselective intermolecular condensation, producing cyclic and acyclic keto-hydrazones with an all-carbon quaternary center in high efficiency and enantioselectivity. The compounds are versatile for preparing multifunctional building blocks and heterocycles with excellent stereoselectivity.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Organic synthesis and anti-influenza A virus activity of cyclobakuchiols A, B, C, and D

Masaki Shoji et al.

Summary: Cyclobakucihols A, B, C, and D were found to inhibit influenza A viral infection and growth, decrease the expression of viral mRNAs and proteins in infected cells, and reduce the expression of host cell immune response genes. Cyclobakuchiols A, B, and C induced the Nrf2 activation pathway, demonstrating their anti-influenza viral activity involving host cell oxidative stress response.

PLOS ONE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Natural Product Synthesis Enabled by Domino Processes Incorporating a 1,2-Rearrangement Step

Bastien Delayre et al.

Summary: The art of natural product total synthesis is closely associated with the development of novel chemical reactions and strategic use of classic organic reactions. New synthetic methods and domino processes can lead to concise synthesis routes for natural products.

ACS CENTRAL SCIENCE (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Biomimetic Total Synthesis of Enterocin

Lilla Koser et al.

Summary: The first chemical total synthesis of the highly oxygenated polyketide enterocin has been achieved using a late-stage biomimetic reaction cascade. The synthesis involved assembling a pivotal precursor from three readily available building blocks, with a chiral dithioacetal representing the core fragment. Additional building blocks were attached to both ends of the core fragment through aldol reactions, leading to the installation of four stereogenic centers.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Copper-Nitrene-Catalyzed Desymmetric Oxaziridination/1,2-Alkyl Rearrangement of 1,3-Diketones toward Bicyclic Lactams

Xue Han et al.

Summary: A novel copper-nitrene-catalyzed desymmetric oxaziridination reaction was reported, producing a synthetically challenging chiral bicyclic lactam. This enriches the asymmetric reactions involving copper-nitrene and provides an alternative strategy for addressing the challenges of catalytic asymmetric Schmidt reactions. This unique reaction could inspire further investigation into novel copper-nitrene-catalyzed asymmetric transformations and their reaction mechanisms.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Bioactive monoterpene phenol dimers from the fruits of Psoralea corylifolia L.

Hu-Tong-Yue Gao et al.

Summary: Nine new compounds were isolated from Psoralea corylifolia fruits, showing varying degrees of PTP1B inhibitory activity. Compounds 5 and 9 exhibited significant inhibition, with molecular docking simulations indicating low binding affinities to PTP1B.

BIOORGANIC CHEMISTRY (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Carbonyl-Olefin Metathesis

Haley Albright et al.

Summary: This Review describes the development of strategies for carbonyl-olefin metathesis reactions and provides a comprehensive overview of currently available methods. The field has expanded significantly over the past eight years from stoichiometric reaction protocols to efficient catalytic strategies for various types of metathesis reactions. The aim of the Review is to capture the current status quo and contribute to further advancements in carbonyl-olefin metathesis in the future.

CHEMICAL REVIEWS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Carbonyl umpolung as an organometallic reagent surrogate

Xi-Jie Dai et al.

Summary: Construction of new carbon-carbon bonds is essential in organic chemistry, with organometallic reagents being versatile nucleophiles for this purpose. However, the classical organometallic reactions are limited by the dependence on stoichiometric quantities of metals and organic halides, leading to copious amounts of metal halide waste.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Recent advances in the chemistry of ketyl radicals

Aron Peter et al.

Summary: Ketyl radicals are important reactive intermediates in synthesis, which can be generated through various methods and play crucial roles in new synthetic protocols. Research focuses on innovation in generation pathways, applications in new synthetic schemes, strategies for enantioselectivity control, and detailed reaction mechanisms.

CHEMICAL SOCIETY REVIEWS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

The organocatalytic enantiodivergent fluorination of β-ketodiaryl-phosphine oxides for the construction of carbon-fluorine quaternary stereocenters

Shaolei Xie et al.

Summary: Commercially available cinchona alkaloids have been developed to catalyze the enantiodivergent fluorination of beta-ketodiarylphosphine oxides for constructing carbon-fluorine quaternary stereocenters, showing broad substrate scope, excellent enantioselectivities, and scalability.

CHEMICAL COMMUNICATIONS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Total synthesis of the complex taxane diterpene canataxpropellane

Fabian Schneider et al.

SCIENCE (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Multiple Catalytic C-H Bond Functionalization for Natural Product Synthesis

Olivier Baudoin

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Conformational Design Principles in Total Synthesis

Renzhi Chen et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Recent achievements and current trajectories of diversity-oriented synthesis

Christopher J. Gerry et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2020)

添加到收藏夹

Article Chemistry, Organic

Two-Phase Total Synthesis of Taxanes: Tactics and Strategies

Yuzuru Kanda et al.

JOURNAL OF ORGANIC CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Organic

Transition-Metal-Free Site-Selective γ-C(sp2)-H Monoiodination of Arenes Directed by an Aliphatic Keto Group

Hong-Li Bian et al.

ORGANIC LETTERS (2020)

添加到收藏夹

Article Chemistry, Organic

Meroterpenoids from the fruits of Psoralea corylifolia

Qing-Xia Xu et al.

TETRAHEDRON (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Computational planning of the synthesis of complex natural products

Barbara Mikulak-Klucznik et al.

NATURE (2020)

添加到收藏夹

Article Chemistry, Organic

Synthetic Strategy: Palladium-Catalyzed Dehydrogenation of Carbonyl Compounds

Toshikazu Hirao

JOURNAL OF ORGANIC CHEMISTRY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Structure-Pattern-Based Total Synthesis

Christa K. G. Gerlinger et al.

CHEMISTRY-A EUROPEAN JOURNAL (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (-)-morphine

Qing Zhang et al.

NATURE COMMUNICATIONS (2019)

添加到收藏夹

Article Chemistry, Organic

Catalytic Asymmetric Total Syntheses of (-)-Galanthamine and (-)-Lycoramine

Qing Zhang et al.

JOURNAL OF ORGANIC CHEMISTRY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

A robotic platform for flow synthesis of organic compounds informed by AI planning

Connor W. Coley et al.

SCIENCE (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Transition-metal-free α-arylation of nitroketones with diaryliodonium salts for the synthesis of tertiary α-aryl, α-nitro ketones

Yang An et al.

CHEMICAL COMMUNICATIONS (2019)

添加到收藏夹

Review Chemistry, Multidisciplinary

Total Synthesis Endeavors and Their Contributions to Science and Society: A Personal Account

K. C. Nicolaou et al.

CCS CHEMISTRY (2019)

添加到收藏夹

Review Chemistry, Medicinal

Psoralea corylifolia L: Ethnobotanical, biological, and chemical aspects: A review

Fiaz Alam et al.

PHYTOTHERAPY RESEARCH (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Divergent Strategy in Natural Product Total Synthesis

Lei Li et al.

CHEMICAL REVIEWS (2018)

添加到收藏夹

Article Chemistry, Organic

Catalytic Asymmetric Synthesis of 3,4-Disubstituted Cyclohexadiene Carbaldehydes: Formal Total Synthesis of Cyclobakuchiols A and C

Vidyasagar Maurya et al.

ORGANIC LETTERS (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Computational chemistry strategies in natural product synthesis

Masha Elkin et al.

CHEMICAL SOCIETY REVIEWS (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

p- Toluenesulfonic acid catalysed fluorination of alpha-branched ketones for the construction of fluorinated quaternary carbon centres

Shi-Zhong Tang et al.

CHEMICAL COMMUNICATIONS (2018)

添加到收藏夹

Article Chemistry, Organic

Copper-Assisted Direct Nitration of Cyclic Ketones with Ceric Ammonium Nitrate for the Synthesis of Tertiary α-Nitro-α-substituted Scaffolds

Zhi-Oiang Zhang et al.

ORGANIC LETTERS (2017)

添加到收藏夹

Review Chemistry, Applied

A Simple and Efficient Method for the Preparation of α-Halogenated Ketones Using Iron(III) Chloride and Iron(III) Bromide as Halogen Sources with Phenyliodonium Diacetate as Oxidant

Shi-Zhong Tang et al.

ADVANCED SYNTHESIS & CATALYSIS (2017)

添加到收藏夹

Review Integrative & Complementary Medicine

The Chemical Constituents and Bioactivities of Psoralea corylifolia Linn.: A Review

Xuenong Zhang et al.

AMERICAN JOURNAL OF CHINESE MEDICINE (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

A Cu-mediated one-pot Michael addition/alpha-arylation strategy using a diaryliodonium salt: a direct and efficient approach to alpha-aryl-beta-substituted cyclic ketone scaffolds

Jin-Long Pan et al.

CHEMICAL COMMUNICATIONS (2016)

添加到收藏夹

Article Chemistry, Organic

Construction of Stereogenic α,α-Disubstituted Cycloalkanones via 1° Amine Thiourea Dual Catalysis: Experimental Scope and Computational Analyses

Jun Yong Kang et al.

JOURNAL OF ORGANIC CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Organic

Iron(III) chloride hexahydrate-promoted selective hydroxylation and chlorination of benzyl ketone derivatives for the construction of heteroquaternary scaffolds

Tao Chen et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2016)

添加到收藏夹

Article Chemistry, Organic

Iron-Catalyzed α-Arylation of Deoxybenzoins with Arenes through an Oxidative Dehydrogenative Approach

Tao Chen et al.

ORGANIC LETTERS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Palladium-Catalyzed Decarbonylative Dehydration for the Synthesis of α-Vinyl Carbonyl Compounds and Total Synthesis of (-)-Aspewentins A, B, and C

Yiyang Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

添加到收藏夹

Article Chemistry, Organic

Further study on synthesis of the cyclobakuchiols

Hidehisa Kawashima et al.

TETRAHEDRON (2015)

添加到收藏夹

Article Chemistry, Multidisciplinary

Synthesis of Cyclobakuchiols A, B, and C by Using Conformation-Controlled Stereoselective Reactions

Hidehisa Kawashima et al.

CHEMISTRY-A EUROPEAN JOURNAL (2014)

添加到收藏夹

Article Chemistry, Organic

Scalable Asymmetric Total Syntheses of (+)-Psoracorylifol B and (+)-ent-Psoracorylifol C

Jingyun Ren et al.

ORGANIC LETTERS (2014)

添加到收藏夹

Article Chemistry, Medicinal

Isolation of a new meroterpene and inhibitors of nitric oxide production from Psoralea corylifolia fruits guided by TLC bioautography

Guodong Xiao et al.

FITOTERAPIA (2012)

添加到收藏夹

Article Chemistry, Organic

Primary Amine, Thiourea-Based Dual Catalysis Motif for Synthesis of Stereogenic, All-Carbon Quaternary Center-Containing Cycloalkanones

Jun Yong Kang et al.

ORGANIC LETTERS (2012)

添加到收藏夹

Review Chemistry, Multidisciplinary

Redox Economy in Organic Synthesis

Noah Z. Burns et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2009)

添加到收藏夹

Editorial Material Chemistry, Multidisciplinary

Synthesizing our future

Ryoji Noyori

NATURE CHEMISTRY (2009)

添加到收藏夹

Review Chemistry, Multidisciplinary

Function-oriented synthesis, step economy, and drug design

Paul A. Wender et al.

ACCOUNTS OF CHEMICAL RESEARCH (2008)

添加到收藏夹

Article Chemistry, Organic

An expedient one-pot entry to catecholestrogens and other catechol compounds via IBX-mediated phenolic oxygenation

A Pezzella et al.

TETRAHEDRON LETTERS (2005)

添加到收藏夹

Article Chemistry, Multidisciplinary

Iodine(V) reagents in organic synthesis.: Part 4.: o-iodoxybenzoic acid as a chemospecific tool for single electron transfer-based oxidation processes

KC Nicolaou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)

添加到收藏夹

Article Chemistry, Multidisciplinary

A new method for the one-step synthesis of α,β-unsaturated carbonyl systems from saturated alcohols and carbonyl compounds

KC Nicolaou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.