4.7 Review

Nox and renal disease

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Thomas Schaldecker et al.

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NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs

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Persistent oxidative stress following renal ischemia-reperfusion injury increases ANG II hemodynamic and fibrotic activity

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Angiotensin II stimulates epithelial sodium channels in the cortical collecting duct of the rat kidney

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Dexamethasone increases ROS production and T cell suppressive capacity by anti-inflammatory macrophages

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Subcellular localization of Nox4 and regulation in diabetes

Karen Block et al.

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Ravi Nistala et al.

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Lipid rafts keep NADPH oxidase in the inactive state in human renal proximal tubule cells

Weixing Han et al.

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RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis

Jiancheng Guo et al.

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Masao Tsujihata et al.

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Phosphatidylinositol (4,5)-bisphosphate Modulates Nox5 Localization via an N-Terminal Polybasic Region

Tsukasa Kawahara et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

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Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury

Guohui Ren et al.

MOLECULAR IMMUNOLOGY (2008)

Article Urology & Nephrology

Angiotensin-(1-7) prevents activation of NADPH oxidase and renal vascular dysfunction in diabetic hypertensive rats

Ibrahim F. Benter et al.

AMERICAN JOURNAL OF NEPHROLOGY (2008)

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Dual effects of RAS blockade on blood pressure and podocyte function

Jocben Reiser et al.

CURRENT HYPERTENSION REPORTS (2007)

Article Medicine, Research & Experimental

Macrophages suppress T cell responses and arthritis development in mice by producing reactive oxygen species

Kyra A. Gelderman et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

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Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy

J. David Lambeth

FREE RADICAL BIOLOGY AND MEDICINE (2007)

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Role of gp91phox-containing NADPH oxidase in mediating the effect of K restriction on ROMK channels and renal K excretion

Elisa Babilonia et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

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Depolarization of the macula densa induces superoxide production via NAD(P)H oxidase

Ruisheng Liu et al.

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p22phox in the macula densa regulates single nephron GFR during angiotensin II infusion in rats

Pouneh Nouri et al.

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NAD(P)H Oxidases regulate HIF-2α protein expression

Karen Block et al.

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Novel mechanism of activation of NADPH oxidase 5 - Calcium sensitization via phosphorylation

Davin Jagnandan et al.

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Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin

Luca Musante et al.

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NADPH oxidase subunits (NOX-1, p22phox, Rac-1) and tacrolimus-induced nephrotoxicity in a rat renal transplant model

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NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)

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NADPH oxidase p22phox and catalase gene variants are associated with biomarkers of oxidative stress and adverse outcomes in acute renal failure

Mary C. Perianayagam et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

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Induction of TRPC6 channel in acquired forms of proteinuric kidney disease

Clemens C. Moeller et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)

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RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response

P Modlinger et al.

HYPERTENSION (2006)

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D-5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure

ZW Yang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2006)

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NADPH oxidases in the kidney

Pritmohinder S. Gill et al.

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Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney

Y Gorin et al.

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Experimental membranous nephropathy redux

AV Cybulsky et al.

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Cross talk between the intrarenal dopaminergic and cyclooxygenase-2 systems

MZ Zhang et al.

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D-5 dopamine receptor regulation of phospholipase D

ZW Yang et al.

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HIF activation by pH-dependent nucleolar sequestration of VHL

K Mekhail et al.

NATURE CELL BIOLOGY (2004)

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Superoxide enhances tubuloglomerular feedback by constricting the afferent arteriole

RS Liu et al.

KIDNEY INTERNATIONAL (2004)

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Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats

S Hoffmann et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)

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Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxiainducible factor 1 via increase in reactive oxygen species

P Goyal et al.

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Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells

Y Gorin et al.

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Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression

T Chabrashvili et al.

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Cyclosporin A disrupts bradykinin signaling through superoxide

M Vetter et al.

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Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage

DP Basile et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)

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Redox regulation of the afferent arteriole and tubuloglomerular feedback

CS Wilcox

ACTA PHYSIOLOGICA SCANDINAVICA (2003)

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Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo

M Wingler et al.

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Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function

DP Basile et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2001)

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Identification of Renox, an NAD(P)H oxidase in kidney

M Geiszt et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)