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Article
Immunology
Nawal Al Kaabi et al.
Summary: This study evaluated the efficacy and adverse events of booster doses of two inactivated COVID-19 vaccines. The results showed that booster doses provided more effective protection against COVID-19 and were well tolerated.
Review
Public, Environmental & Occupational Health
Saira Naseer et al.
Summary: COVID-19 is considered the most significant threat since World War II, and it is also the biggest global health disaster of the century. It originated in Wuhan City, Hubei Province, China in December 2019 and has been named by the World Health Organization. It is spreading rapidly across the globe, posing significant challenges to health, economy, and society.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Public, Environmental & Occupational Health
Shama Perveen et al.
Summary: This study in Pakistan reveals hesitancy and inequality as major obstacles to successful COVID-19 vaccination delivery, with reluctance stemming from conspiracy theories and religious beliefs, and unequal accessibility posing significant barriers. Recommendations include mobilizing community influence, utilizing social and mass media for public education, as well as engaging religious leaders to endorse vaccination efforts, with future research suggested to explore equitable distribution of vaccines in various regions.
JOURNAL OF COMMUNITY PSYCHOLOGY
(2022)
Review
Medicine, General & Internal
Yunus A. Luqmani et al.
Summary: COVID-19 has rapidly spread worldwide, affecting human lives, economies, and societies. A deluge of information from various sources has caused confusion and entangled facts and perceptions. Global vaccination is the realistic solution to control the infection, but it faces public controversy and concerns. This review highlights the challenges in handling the COVID-19 crisis and provides a rational perspective.
MEDICAL PRINCIPLES AND PRACTICE
(2022)
Review
Health Care Sciences & Services
Seyed A. Nejadghaderi et al.
Summary: The COVID-19 pandemic has impacted almost all countries and territories around the world. Many countries have implemented similar strategies to control and reduce the spread of the virus, with differences in the burden of COVID-19 possibly attributed to the strictness of implementation of strategies. Systemic rather than regional strategies are needed to address limitations at the national level.
INTERNATIONAL JOURNAL OF HEALTH SERVICES
(2022)
Review
Multidisciplinary Sciences
Steven Kwasi Korang et al.
Summary: This study assessed the effectiveness and safety of COVID-19 vaccines through analyses of randomized clinical trials. The findings suggest that all included vaccines are effective in preventing COVID-19, with mRNA vaccines being most effective in prevention and viral vector vaccines being most effective in reducing mortality. However, further trials and longer follow-up are needed to better understand the safety profile of these vaccines.
Article
Biotechnology & Applied Microbiology
Haya Omeish et al.
Summary: The study found that people in Jordan experienced more side effects with the AstraZeneca vaccine followed by the Pfizer vaccine and the least one is the Sinopharm vaccine. These side effects include symptoms such as pain at the injection site, fatigue, headache, and nausea, with most individuals not considering them severe.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Environmental Sciences
Rubeena Zakar et al.
Summary: COVID-19 vaccination acceptance or hesitancy is associated with several socio-demographic factors, including gender, age, education level, employment status, socioeconomic status, residential area, media exposure, history of influenza vaccination, physical activity, and perceived health status.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Medicine, General & Internal
Baoqi Zeng et al.
Summary: This study conducted a systematic review and meta-analysis to assess the effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern (VOC). The results showed that full vaccination was highly effective against the Alpha variant and moderately effective against the Beta, Gamma, and Delta variants. Booster vaccination was more effective against the Delta and Omicron variants. mRNA vaccines appeared to have higher effectiveness against the VOC compared to other vaccines.
Review
Public, Environmental & Occupational Health
Sumaira Khalid et al.
Summary: This minireview summarizes the main findings, features, limitations, and gaps in the current epidemiological research on COVID-19 vaccine hesitancy in the Pakistani population. The reported vaccine hesitancy in the population shows significant heterogeneity, and the included co-variables do not explain the observed variance. The authors conclude that in-depth analysis of COVID-19 vaccine hesitancy in a representative sample of the Pakistani population is crucial, as it will help measure the magnitude of vaccine hesitancy and identify its determinants.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Immunology
Muhammad Salman et al.
Summary: This study aimed to understand people's beliefs in COVID-19-related conspiracy theories, their vaccine hesitancy, views on vaccine mandates, and willingness to pay for vaccines. The findings showed a high prevalence of conspiracy beliefs and vaccine hesitancy in the targeted countries, highlighting the need for aggressive measures to counter these issues.
Article
Multidisciplinary Sciences
Samar Fatima et al.
Summary: Although vaccinated patients may still develop severe and critical COVID-19 infection, the proportion is lower compared to the unvaccinated population. Efforts should be made to vaccinate as many individuals as possible and develop more effective vaccines to reduce the high death toll of COVID-19 infection.
Article
Immunology
Mohamed A. Baraka et al.
Summary: This study surveyed COVID-19 patients in Pakistan to assess vaccine acceptance and hesitancy. The majority of hospitalized patients were unvaccinated, but those willing to be vaccinated saw vaccines as an effective protection against COVID-19. Older patients from urban areas were more likely to receive the vaccine, while those with no formal education had higher hesitancy. Social media was not their main source of vaccine information.
Article
Medicine, General & Internal
Tauqeer Hussain Mallhi et al.
Summary: A questionnaire-based study was conducted to investigate the side effects of COVID-19 vaccines among individuals with chronic illnesses in Saudi Arabia. The study found that there were transient and short-lived side effects, which were comparable to the safety reports of phase 3 clinical trials of Pfizer and AstraZeneca vaccines. The frequency of side effects was associated with certain demographics, indicating the need for further investigations.
MEDICINA-LITHUANIA
(2022)
Article
Infectious Diseases
Shengli Xia et al.
Summary: The inactivated SARS-CoV-2 vaccine, BBIBP-CorV, demonstrated safety and immunogenicity in two age groups. Humoral responses against SARS-CoV-2 were induced in all vaccine recipients by day 42. A two-dose immunisation with 4 mu g vaccine on days 0 and 21 or days 0 and 28 achieved higher neutralising antibody titres compared to other dosing schedules.
LANCET INFECTIOUS DISEASES
(2021)
Article
Environmental Sciences
Rizwan Rasheed et al.
Summary: The COVID-19 pandemic has significantly impacted the economy of Pakistan, leading to a rise in poverty levels due to social measures, while simultaneously improving urban air quality.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Medicine, General & Internal
Carl A. B. Pearson et al.
Summary: This study analyzed the health and economic impact of different COVID-19 vaccination scenarios in Sindh Province, Pakistan, projecting that vaccination with optimistic vaccine scenarios can have considerable health impacts and be cost-effective. Prioritizing older, high-risk populations may have a smaller advantage in generally younger populations, especially in low- and middle-income countries where transmission rates are higher. Ultimately, the effectiveness and cost-effectiveness of vaccination programs depend on various factors such as vaccine performance, distribution, and future pandemic trends.
Article
Infectious Diseases
Mahmoodullah Azimi et al.
Summary: The study evaluated adverse reactions associated with COVID-19 vaccination among Kabul University of Medical Sciences staff, finding that common reactions included muscle pain, fever, and fatigue. Adverse reactions were more frequent in participants aged 40 or younger, with most reactions being mild to moderate in severity.
INFECTION AND DRUG RESISTANCE
(2021)
Review
Immunology
Shahad Saif Khandker et al.
Summary: COVID-19 vaccines are crucial in preventing the spread of the pandemic, with various vaccine candidates being developed using different strategies. Global variant surveillance and systematic adjustment of vaccines, along with diverse vaccination approaches, are essential to halt the spread of the virus effectively.
Article
Multidisciplinary Sciences
Md Saiful Islam et al.
Summary: Tracking COVID-19 vaccine misinformation in real-time is essential in combating vaccine hesitancy. Among 637 vaccine-related items identified in 52 countries, the majority were rumors, with a high prevalence of false information.
Review
Chemistry, Medicinal
Zhi-Peng Yan et al.
Summary: Various strategies, including vaccine development, have been designed to contain the COVID-19 pandemic. This study reviews the most recent data of 12 vaccines to evaluate their efficacy, safety profile, and usage in various populations, highlighting the importance of comparing protective efficacy and risks of vaccination for global control through herd immunity.
Article
Medicine, General & Internal
Nawal Al Kaabi et al.
Summary: This interim analysis of an ongoing randomized trial in the UAE and Bahrain evaluated the efficacy of two inactivated COVID-19 vaccines in preventing symptomatic cases and adverse events in healthy adults. The study found that both vaccines significantly reduced the risk of symptomatic COVID-19 compared to the control group, with efficacy rates of 72.8% and 78.1%. Serious adverse events were rare across all groups.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Medicine, General & Internal
Mine Durusu Tanriover et al.
Summary: The study presented the interim efficacy and safety results of the CoronaVac vaccine in a phase 3 clinical trial in Turkey, demonstrating high efficacy against PCR-confirmed symptomatic COVID-19 with good safety and tolerability profile. Results showed significant differences in the frequency of any adverse events between the vaccine and placebo groups, indicating excellent protective effects of the vaccine.
Article
Infectious Diseases
Bihua Han et al.
Summary: The study evaluated the safety, tolerability, and immunogenicity of the candidate COVID-19 vaccine CoronaVac containing inactivated SARS-CoV-2 in children and adolescents aged 3-17 years. The research findings indicate that the 3.0 μg dose induced higher levels of neutralizing antibodies compared to the 1.5 μg dose, supporting the use of the 3.0 μg dose for further studies in this age group.
LANCET INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Sana Abbas et al.
Summary: This study aimed to determine the immediate side effects of COVID-19 vaccination in the Pakistani population. Results showed that fever, soreness, redness, and swelling at the injection site were the most common side effects, with younger participants more likely to experience gastrointestinal disturbance and flu-like symptoms.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2021)
Editorial Material
Immunology
Adeel Siddiqui et al.
Article
Medicine, General & Internal
Mohamed Adam et al.
Summary: The study found that the most common side effects reported by participants in the Aseer region of Saudi Arabia after receiving the COVID-19 vaccines were fever, myalgia, malaise, muscle and joint pain, and headache. Symptoms were more common in males than in females. Despite a certain infection rate, the side effects of COVID-19 vaccines were consistent with the manufacturers' data.
PATIENT PREFERENCE AND ADHERENCE
(2021)
Review
Environmental Sciences
Salman Bin Naeem et al.
Summary: The low digital health literacy has a significant impact on the spread of COVID-19-related online misinformation, influenced by the 'viral' nature of social media sharing. The paper suggests a synergistic approach to tackle online health misinformation and mitigate its negative effects in COVID-19 and future pandemics.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Immunology
Ma'mon M. Hatmal et al.
Summary: The study confirms the safety of authorized COVID-19 vaccines, with most side effects being mild to moderate, indicating the body's immune system is building protection. Many individuals feel more reassured after vaccination and recommend others to get vaccinated.
Article
Public, Environmental & Occupational Health
Yusra Habib Khan et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2020)
Article
Health Care Sciences & Services
Bhupendra Kumar Verma et al.
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2020)
