4.2 Article

Therapeutic Drug Monitoring of Blood Sirolimus and Tacrolimus Concentrations for Polypharmacy Management in a Lymphangioleiomyomatosis Patient Taking Two Cytochrome P450 3A Inhibitors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Pharmacology & Pharmacy

PharmVar GeneFocus: CYP3A5

Cristina Rodriguez-Antona et al.

Summary: This article introduces the star (*) allele nomenclature for the polymorphic human CYP3A5 gene in PharmVar, and summarizes the standardized nomenclature of this gene. Additionally, it discusses recent changes and updates, including the retirement of several allelic variants, and provides an overview of how the PharmVar CYP3A5 star allele nomenclature is utilized by PharmGKB and CPIC.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2022)

Article Pharmacology & Pharmacy

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation

Masaki Kumondai et al.

Summary: CYP3A4 is a key enzyme involved in drug metabolism, with variations in its activity leading to interindividual differences in drug efficacy and adverse effects. This study identified new CYP3A4 variants in Japanese individuals and assessed their enzymatic activities, providing insights into the mechanisms underlying differences in CYP3A4-dependent drug metabolism.

DRUG METABOLISM AND DISPOSITION (2021)

Article Medical Laboratory Technology

Effect of CYP3A4 and CYP3A5 Genetic Polymorphisms on the Pharmacokinetics of Sirolimus in Healthy Chinese Volunteers

Jing Zhang et al.

THERAPEUTIC DRUG MONITORING (2017)

Article Multidisciplinary Sciences

Lung Transplantation for Lymphangioleiomyomatosis in Japan

Katsutoshi Ando et al.

PLOS ONE (2016)

Article Biochemistry & Molecular Biology

Capability of Utilizing CYP3A5 Polymorphisms to Predict Therapeutic Dosage of Tacrolimus at Early Stage Post-Renal Transplantation

Takenori Niioka et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)

Review Public, Environmental & Occupational Health

Clinical features, epidemiology, and therapy of lymphangioleiomyomatosis

Angelo M. Taveira-DaSilva Joel Moss

CLINICAL EPIDEMIOLOGY (2015)

Article Pharmacology & Pharmacy

The Effects of CYP3A4 Induction and Inhibition on the Pharmacokinetics of Alisporivir in Humans

Avantika Barve et al.

CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT (2015)

Article Medical Laboratory Technology

CYP3A5*3 and POR*28 Genetic Variants Influence the Required Dose of Tacrolimus in Heart Transplant Recipients

Dorothea Lesche et al.

THERAPEUTIC DRUG MONITORING (2014)

Article Pharmacology & Pharmacy

Rate of onset of inhibition of gut-wall and hepatic CYP3A by clarithromycin

Sara K. Quinney et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2013)

Article Medicine, General & Internal

Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis

Francis X. McCormack et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Pharmacology & Pharmacy

Physiologically Based Pharmacokinetic Model of Mechanism-Based Inhibition of CYP3A by Clarithromycin

Sara K. Quinney et al.

DRUG METABOLISM AND DISPOSITION (2010)

Article Pharmacology & Pharmacy

Sirolimus-itraconazole interaction in a hematopoietic stem cell transplant recipient

A Said et al.

PHARMACOTHERAPY (2006)

Article Pharmacology & Pharmacy

Role of itraconazole metabolites in CYP3A4 inhibition

N Isoherranen et al.

DRUG METABOLISM AND DISPOSITION (2004)

Article Pharmacology & Pharmacy

Clinical pharmacokinetics and therapeutic drug monitoring of sirolimus

A MacDonald et al.

CLINICAL THERAPEUTICS (2000)