期刊
ADVANCES IN NUTRITION
卷 7, 期 2, 页码 383-389出版社
OXFORD UNIV PRESS
DOI: 10.3945/an.115.010595
关键词
phytochemical; natural product integrity; reproducibility; quantitative analysis; orthogonal methods
资金
- American Society for Nutrition (ASN) Nutritional Sciences Council
- Dietary Bioactive Components Research Interest Section (RIS)
Inconsistent and contradictory results from nutrition studies conducted by different investigators continue to emerge, in part because of the inherent variability of natural products, as well as the unknown and therefore uncontrolled variables in study populations and experimental designs. Given these challenges inherent in nutrition research, it is critical for the progress of the field that researchers strive to minimize variability within studies and enhance comparability between studies by optimizing the characterization, control, and reporting of products, reagents, and model systems used, as well as the rigor and reporting of experimental designs, protocols, and data analysis. Here we describe some recent developments relevant to research on plant-derived products used in nutrition research, highlight some resources for optimizing the characterization and reporting of research using these products, and describe some of the pitfalls that may be avoided by adherence to these recommendations.
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