Clinical effects of sodium hyaluronate combined with platelet-rich plasma injection on rotator cuff injury in arthroscopic repair

Review Sport Sciences

Arthroscopic Rotator Cuff Repair A Review of Surgical Techniques and Outcomes

Michael R. Mancini et al.

CLINICS IN SPORTS MEDICINE (2023)

Article Health Care Sciences & Services

Effect of pectoralis minor relaxation on the prognosis of rotator cuff injury under arthroscopy

Shunling Chen et al.

Summary: The addition of pectoralis minor relaxation to arthroscopic surgery is beneficial for the recovery of shoulder joint function and reduction of pain in patients with rotator cuff injury.

ANNALS OF PALLIATIVE MEDICINE (2022)

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Article Orthopedics

Translational therapy from preclinical animal models for muscle degeneration after rotator cuff injury

Qian Liu et al.

Summary: This review summarizes the preclinical animal studies on the degenerative changes in rotator cuff muscles after injury and focuses on potential therapeutic targets or agents to prevent or reverse muscle atrophy and fatty infiltration. These findings have translational potential for the treatment of rotator cuff disorders.

JOURNAL OF ORTHOPAEDIC TRANSLATION (2022)

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Review Orthopedics

Efficacy and safety of platelet-rich plasma combined with hyaluronic acid versus platelet-rich plasma alone for knee osteoarthritis: a systematic review and meta-analysis

Qing Zhang et al.

Summary: This meta-analysis suggests that platelet-rich plasma (PRP) combined with hyaluronic acid (HA) treatment is not superior to PRP alone in relieving pain and improving function in knee osteoarthritis (KOA) patients. However, combined PRP with HA injections is generally safer than PRP injections alone.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2022)

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Review Medicine, General & Internal

Clinical efficacy of different shoulder joint drug injections for rotator cuff injuries: A network meta-analysis

Fang Zhi et al.

Summary: This study conducted a network meta-analysis to comprehensively compare the effectiveness of drug injection therapies for rotator cuff injuries. The results showed that the combination of corticosteroid injections and hyaluronic acid injections can be used for the non-surgical conservative clinical management of rotator cuff injuries.

MEDICINE (2022)

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Article Orthopedics

Hyaluronic acid and platelet-rich plasma for the management of knee osteoarthritis

Ron Gilat et al.

Summary: Intra-articular injections of hyaluronic acid (HA) and platelet-rich plasma (PRP) have shown short-term improvement in pain and function for patients with symptomatic knee osteoarthritis. PRP injections, particularly with leukocyte-poor formulations, may provide greater therapeutic relief. Combination formulations of HA-PRP conjugates may also have a synergistic effect for clinically significant improvement in pain and function. Further studies on the efficacy of HA-PRP conjugates are warranted.

INTERNATIONAL ORTHOPAEDICS (2021)

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Review Orthopedics

Double-Row Rotator Cuff Repair Enhanced With Platelet-Rich Therapy Reduces Retear Rate: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Gregorio Alejandro Villarreal-Villarreal et al.

Summary: The meta-analysis of 9 RCTs showed that using PRT in double-row RCR can significantly reduce retear rates in all sizes of rotator cuff tears. The best outcomes were seen in linked double-row RCR and when PRT was applied during the surgical procedure and in the tendon-bone interface. All patients improved clinically and achieved optimal values for patient-reported outcomes measures.

ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY (2021)

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Article Multidisciplinary Sciences

Comparing efficacy of intraarticular single crosslinked Hyaluronan (HYAJOINT Plus) and platelet-rich plasma (PRP) versus PRP alone for treating knee osteoarthritis

Shu-Fen Sun et al.

Summary: The study compared the efficacy of combined injections of HYAJOINT Plus and PRP with single PRP injections in patients with knee osteoarthritis. The results showed that the combined injection group achieved better pain reduction on the VAS scale at 6 months.

SCIENTIFIC REPORTS (2021)

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Article Orthopedics

Arthroscopic Side-to-Side Repair of Massive Rotator Cuff Tears Maintains Adequate Functional Improvement at 12 to 14 Years' Follow-up

Marie Caroline Merlet et al.

Summary: The study evaluated long-term clinical and radiographic outcomes of arthroscopic side-to-side repair for massive rotator cuff tears. At a minimum follow-up of 12 years, patients maintained satisfactory clinical scores despite a high retear incidence. Repair is a safe and effective treatment for massive rotator cuff tears, offering a less invasive and complex alternative to other procedures.

AMERICAN JOURNAL OF SPORTS MEDICINE (2021)

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Article Orthopedics

Platelet-Rich Plasma in Patients With Partial-Thickness Rotator Cuff Tears or Tendinopathy Leads to Significantly Improved Short-Term Pain Relief and Function Compared With Corticosteroid Injection: A Double-Blind Randomized Controlled Trial

Cory A. Kwong et al.

Summary: The study aimed to compare the effects of PRP and CS injections in providing pain relief and improved function in patients with rotator cuff tendinopathy and partial-thickness rotator cuff tears. The results showed that patients in the PRP group had better pain and function improvement in short-term follow-up, but no sustained benefit over CS in longer-term follow-up.

ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY (2021)

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Article Orthopedics

The effect of physiotherapy in rotator cuff injury patients with platelet-rich plasma: study protocol of a non-randomized controlled trial

Chi Zhang et al.

Summary: This study aims to determine whether Platelet-Rich Plasma (PRP) combined with early physiotherapy is more effective than PRP alone for rotator cuff injury patients; Constant-Murley score, Visual Analogue Scale, and MOS Item Short-form Health Survey were used to evaluate the effects; results will provide information on the effects of PRP and physiotherapy on rotator cuff injuries.

BMC MUSCULOSKELETAL DISORDERS (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

The Evolving Roles of MRI and Ultrasound in First-Line Imaging of Rotator Cuff Injuries

Adam C. Zoga et al.

Summary: This article discusses the importance of imaging diagnosis for rotator cuff tears, emphasizing the roles of MRI and ultrasound in identifying such tears, along with their different costs and advantages and shortcomings. The article also suggests optimizing the quality of ultrasound examinations to increase confidence in its diagnostic capabilities.

AMERICAN JOURNAL OF ROENTGENOLOGY (2021)

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Article Medicine, General & Internal

Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy A Randomized Clinical Trial

Rebecca S. Kearney et al.

Summary: This study compared the effects of a single platelet-rich plasma injection with a sham injection on patients with midportion Achilles tendinopathy. Results showed no significant difference in Achilles tendon dysfunction at the 6-month follow-up between the two groups. Therefore, the use of a single platelet-rich plasma injection does not appear to be an effective treatment for chronic midportion Achilles tendinopathy.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Review Cell & Tissue Engineering

Mesenchymal stem cell-derived exosomes: therapeutic implications for rotator cuff injury

Jinbing He et al.

Summary: Rotator cuff injuries are a common clinical condition of the shoulder joint, with surgical reattachment of torn tendons having a lower success rate. Various techniques, including genetic interventions and cell transplantation, have been explored to promote healing, with recent focus on mesenchymal stem cells (MSCs) and their potential therapeutic effects in promoting angiogenesis and reducing inflammation.

REGENERATIVE MEDICINE (2021)

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Article Orthopedics

Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study

Haleh Dadgostar et al.

Summary: This study compared the effects of PRP and corticosteroid injections on the structural and clinical changes in RC muscles, finding that PRP may offer more significant improvements in pain and ROM compared to corticosteroids.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)

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Article Pharmacology & Pharmacy

Enhancement of Rotator Cuff Healing with Farnesol-Impregnated Gellan Gum/Hyaluronic Acid Hydrogel Membranes in a Rabbit Model

Yen-Hung Lin et al.

Summary: The study found that hydrogel membranes containing farnesol showed better repair results for rotator cuff injuries in a rabbit model, improving damaged tissues by promoting collagen synthesis and modulating inflammatory factors.

PHARMACEUTICS (2021)

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Article Medicine, General & Internal

Effects of evidence-based nursing combined with enhanced recovery after surgery on shoulder joint function and neurological function after arthroscopic rotator cuff injury repair

Lu He et al.

Summary: The study found that Enhanced Recovery After Surgery (ERAS) nursing combined with limbs training can effectively improve shoulder joint range of motion and neurological function recovery in patients undergoing arthroscopic rotator cuff repair surgery. Additionally, it can reduce the occurrence of complications, demonstrating significant clinical efficacy.

MEDICINE (2021)

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Article Orthopedics