Synthesis of biphenyl-based chiral amine catalysts from dibromopyrenes and their application in enamine catalysis

Novel axially chiral biphenyl-based amine catalysts have been designed and synthesized from dibromopyrenes. These chiral amines function as effective catalysts for asymmetric reactions through enamine intermediates.

Automated summary

Novel axially chiral biphenyl-based amine catalysts were synthesized from dibromopyrenes, and these chiral amines proved to be effective catalysts for asymmetric reactions through enamine intermediates.