期刊
LATIN AMERICAN JOURNAL OF PHARMACY
卷 42, 期 7, 页码 1421-1427出版社
COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES
关键词
anti-biofilm activity; anti-caries activity; Curcuma amada; Streptococcus mutans; Streptococcus ora-lis; Lactobacillus acidophilus
In recent years, cavities have become increasingly common in both children and adults, caused by cariogenic bacteria. Studies have shown that herbal medications, such as Curcuma amada rhizome extract, have significant antibacterial activity against Streptococcus mutans, Streptococcus oralis, and Lactobacillus acidophilus, inhibiting the development of dental caries. The extract also inhibits biofilm production by Streptococci sp., further preventing tooth decay.
In recent years, cavities have grown increasingly prevalent in both children and adults. The destruction of teeth is caused by cariogenic bacteria that produce or promote tooth decay. Recent studies on dental caries have highlighted the importance of herbal medications. The objective of this research was to assess the antibacterial activity of ethanolic extracts of Curcuma amada rhizome against Streptococcus mutans, Streptococcus oralis, and Lactobacillus acidophilus. In contrast to antibiotics, the rhizome extract of Curcuma amada shown significant anti-caries action against Streptococcus mutans, Streptococcus oralis, and Lactobacillus acidophilus. Oral pathogen Streptococci sp. was shown to be strongly inhibited in its biofilm production by this compound. The aforementioned findings shown that Curcuma amada rhizome extract had anti-caries action by inhibiting the development of Streptococcal dental caries.
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