4.2 Article

Increasing age predicts adverse pathology including intraductal carcinoma of the prostate and cribriform patterns in deferred radical prostatectomy after upfront active surveillance for Gleason grade group 1 prostate cancer: analysis of prospective observational study cohort

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Clinical outcomes of intraductal carcinoma or cribriform in radical prostatectomy specimens of men opting for active surveillance: data from the PRIAS-JAPAN study

Yoichiro Tohi et al.

Summary: In intraductal carcinoma of the prostate (IDC-P) and invasive cribriform, which are key prognostic factors for early stage prostate cancer patients, their presence and significance following active surveillance (AS) were examined utilizing radical prostatectomy (RP) specimens in this study. The results confirmed that IDC-P or cribriform comprised approximately one-third of all RP specimens in men who underwent RP following AS, and showed their association with higher Gleason grade and lower PSA recurrence-free survival rates.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2023)

Review Health Care Sciences & Services

Active Surveillance for Prostate Cancer: Past, Current, and Future Trends

Ivo I. de Vos et al.

Summary: Active surveillance (AS) emerged as a treatment modality to combat overtreatment of indolent, low-risk prostate cancer (PCa) due to increased PSA screening. This paper reviews the evolution of AS and its current landscape and challenges.

JOURNAL OF PERSONALIZED MEDICINE (2023)

Article Oncology

Adverse Pathological Findings at Radical Prostatectomy following Active Surveillance: Results from the Movember GAP3 Cohort

Cristina Marenghi et al.

Summary: Active surveillance is a safe option for low-risk prostate cancer patients, and most patients do not show adverse pathological findings at surgery. However, wider entry criteria are associated with higher tumor extension and positive surgical margins.

CANCERS (2022)

Article Urology & Nephrology

Predictors of adverse pathology on radical prostatectomy specimen in men initially enrolled in active surveillance for low-risk prostate cancer

Lars Bjornebo et al.

Summary: The study aimed to evaluate clinical variables, including MRI, for predicting adverse pathology at RP in men initially enrolled in AS. Age, clinical T-stage, PSA, and PI-RADS score were found to be significantly associated with adverse pathology at RP.

WORLD JOURNAL OF UROLOGY (2021)

Article Oncology

Grade group 2 (10% ≥ GP4) patients have very similar malignant potential with grade group 1 patients, given the risk of intraductal carcinoma of the prostate

Masashi Kato et al.

Summary: Patients with GG2 (GP4 <= 10%) and low risk of IDC-P may be candidates for active surveillance, similar to GG1 patients.

INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2021)

Review Urology & Nephrology

EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

Nicolas Mottet et al.

Summary: The 2020 EAU-EANM-ESTRO-ESUR-SIOG guidelines on screening, diagnosis, and treatment of localized prostate cancer summarize the most recent recommendations for clinical practice, including risk-adapted strategies, medical imaging utilization, biopsy techniques, patient classification, and treatment options. Recommendations include consideration of moderate hypofractionation for intermediate-risk patients and a combination of local treatment with long-term hormonal therapy for cN1 PCa patients.

EUROPEAN UROLOGY (2021)

Article Urology & Nephrology

Association of Age With Risk of Adverse Pathological Findings in Men Undergoing Delayed Radical Prostatectomy Following Active Surveillance

Claire M. de la Calle et al.

Summary: Older men with GG1 prostate cancer who undergo delayed radical prostatectomy after active surveillance may have a higher risk of adverse pathology, requiring closer monitoring and additional testing such as mpMRI to improve risk stratification.

UROLOGY (2021)

Article Urology & Nephrology

Clinical-genomic Characterization Unveils More Aggressive Disease Features in Elderly Prostate Cancer Patients with Low-grade Disease

Hanan Goldberg et al.

Summary: Analyzing the impact of age on clinical-genomic prognostic features of aggressiveness in localized prostate cancer, it was found that elderly men with low-risk prostate cancer may have more aggressive disease than younger patients. This suggests a need to reconsider the standard paradigm of elderly prostate cancer patients not aggressively treated based solely on chronological age.

EUROPEAN UROLOGY FOCUS (2021)

Letter Medicine, General & Internal

Use of Active Surveillance or Watchful Waiting for Low-Risk Prostate Cancer and Management Trends Across Risk Groups in the United States, 2010-2015

Brandon A. Mahal et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Article Urology & Nephrology

Long-Term Outcomes after Deferred Radical Prostatectomy in Men Initially Treated with Active Surveillance

Rebecka Arnsrud Godtman et al.

JOURNAL OF UROLOGY (2018)

Article Urology & Nephrology

PI-RADS Prostate Imaging - Reporting and Data System: 2015, Version 2

Jeffrey C. Weinreb et al.

EUROPEAN UROLOGY (2016)