ReACT (redox-activated chemical tagging) chemistry enables direct derivatization and fluorescence detection of S-adenosyl-l-homocysteine (SAH)

S-Adenosyl-l-homocysteine (SAH) is a universal byproduct and product inhibitor of the methyltransferase-catalyzed methylation reaction. Here based on ReACT (redox-activated chemical tagging) chemistry, direct derivatization and fluorescence measurement of SAH were achieved with features such as mild reaction conditions and simple operation.

Automated summary

Direct derivatization and fluorescence measurement of S-Adenosyl-l-homocysteine (SAH) were achieved using ReACT chemistry, which offers mild reaction conditions and simple operation.