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Mycophenolic acid 12-h trough level monitoring in renal transplantation: Association with acute rejection and toxicity
R Borrows et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2006)
Pharmacodynamics of mycophenolate mofetil after nonmyeloablative conditioning and unrelated donor hematopoietic cell transplantation
L Giaccone et al.
BLOOD (2005)
Pharmacokinetics of sirolimus (rapamycin) in subjects with mild to moderate hepatic impairment
JJ Zimmerman et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation
P Jacobson et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)
Antithymocyte globulin pharmacokinetics in pediatric patients after hematopoietic stem cell transplantation
MG Seidel et al.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY (2005)
An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: Evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity
KK Miles et al.
DRUG METABOLISM AND DISPOSITION (2005)
Population pharmacokinetics of mycophenolic acid during the first week after renal transplantation
CE Staatz et al.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Heterogeneous clearance of antithymocyte globulin after CD34+-selected allogeneic hematopoietic progenitor cell transplantation
I Kakhniashvili et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation
RA Nash et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
Control of advanced and refractory acute myelogenous leukaemia with sirolimus-based non-myeloablative allogeneic stem cell transplantation
DF Claxton et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Cyclosporine A and Mycophenolate Mofetil vs Cyclosporine A and Methotrexate for graft-versus-host disease prophylaxis after stem cell transplantation from HLA-identical siblings
F Neumann et al.
BONE MARROW TRANSPLANTATION (2005)
Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2
DA Hesselink et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2005)
The influence of norfloxacin and metronidazole on the disposition of mycophenolate mofetil
OJ Naderer et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Population pharmacokinetics of mycophenolic acid in renal transplant recipients
RM van Hest et al.
CLINICAL PHARMACOKINETICS (2005)
Sirolimus - The evidence for clinical pharmacokinetic monitoring
SB Stenton et al.
CLINICAL PHARMACOKINETICS (2005)
Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism
N Picard et al.
DRUG METABOLISM AND DISPOSITION (2005)
Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease
LJ Johnston et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2005)
Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol
AD Schachter et al.
PEDIATRIC TRANSPLANTATION (2004)
A pilot study of tacrolimus and mycophenolate mofetil graft-versus-host disease prophylaxis in childhood and adolescent allogeneic stem cell transplant recipients
I Osunkwo et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2004)
Randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (Neoral)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year
G Cianci et al.
TRANSPLANTATION (2004)
A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (Neoral) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year
G Ciancio et al.
TRANSPLANTATION (2004)
Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation
C Cutler et al.
BONE MARROW TRANSPLANTATION (2004)
The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants
O Bernard et al.
DRUG METABOLISM AND DISPOSITION (2004)
Pre-transplant inosine monophosphate dehydrogenase activity is associated with clinical outcome after renal transplantation
P Glander et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
HLA matching in allogeneic stem cell transplantation
EW Petersdorf
CURRENT OPINION IN HEMATOLOGY (2004)
Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats
M Kobayashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
A prospective randomized trial comparing cyclosporine and short course methotrexate with cyclosporine and mycophenolate mofetil for GVHD prophylaxis in myeloablative allogeneic bone marrow transplantation
B Bolwell et al.
BONE MARROW TRANSPLANTATION (2004)
Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients
M Schubert et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2004)
Relationship between CsA trough blood concentration and severity of acute graft-versus-host disease after paediatric stem cell transplantation from matched-sibling or unrelated donors
P Martin et al.
BONE MARROW TRANSPLANTATION (2003)
Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil
DRJ Kuypers et al.
THERAPEUTIC DRUG MONITORING (2003)
HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with hematologic malignancies
MB Maris et al.
BLOOD (2003)
Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
JH Antin et al.
BLOOD (2003)
Population pharmacokinetic analysis of mycophenolic acid in renal transplant recipients following oral administration of mycophenolate mofetil
B Shum et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2003)
Pharmacokinetics and pharmacodynamics of anti-thymocyte globulin in recipients of partially HLA-matched blood hematopoietic progenitor cell transplantation
EK Waller et al.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2003)
Pharmacokinetics of alemtuzumab used for in vivo and in vitro T-cell depletion in allogeneic transplantations: relevance for early adoptive immunotherapy and infectious complications
EC Morris et al.
BLOOD (2003)
Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine a because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis
HJPM Koenen et al.
TRANSPLANTATION (2003)
Sirolimus: Its discovery, biological properties, and mechanism of action
SN Sehgal
TRANSPLANTATION PROCEEDINGS (2003)
An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy
M Coen et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2003)
Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MNF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases
D Niederwieser et al.
BLOOD (2003)
Allergic skin and systemic reactions in a patient with pure red cell aplasia and anti-erythropoietin antibodies challenged with different epoetins
G Weber et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2002)
Metabonomics: a platform for studying drug toxicity and gene function
JK Nicholson et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease
AI Benito et al.
TRANSPLANTATION (2001)
Antithymocyte globulin for graft-versus-host disease prophylaxis in transplants from unrelated donors: 2 randomized studies from Gruppo Italiano Trapianti Midollo Osseo (GITMO)
A Bacigalupo et al.
BLOOD (2001)
Improved clinical outcome of paediatric bone marrow recipients using a test dose and Bayesian pharmacokinetic individualization of busulfan dosage regimens
N Bleyzac et al.
BONE MARROW TRANSPLANTATION (2001)
Total and active thymoglobulin levels: effects of dose and sensitization on serum concentrations
JF Regan et al.
TRANSPLANT IMMUNOLOGY (2001)
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects
PA McSweeney et al.
BLOOD (2001)
Pharmacokinetics of intravenous mycophenolate mofetil after allogeneic blood stem cell transplantation
A Jenke et al.
CLINICAL TRANSPLANTATION (2001)
Clinical pharmacokinetics of sirolimus
K Mahalati et al.
CLINICAL PHARMACOKINETICS (2001)
Effects of obesity on pharmacokinetics - Implications for drug therapy
G Cheymol
CLINICAL PHARMACOKINETICS (2000)
Development and application of a high-performance liquid chromatography-based assay for determination of the activity of inosine 5′-monophosphate dehydrogenase in whole blood and isolated mononuclear cells
W Albrecht et al.
THERAPEUTIC DRUG MONITORING (2000)
Mycophenolate mofetil for the prophylaxis of acute GVHD in HLA-mismatched bone marrow transplant patients
N Basara et al.
CLINICAL TRANSPLANTATION (2000)
Mycophenolate mofetil in stem cell transplant patients in relation to plasma level of active metabolite
MG Kiehl et al.
CLINICAL BIOCHEMISTRY (2000)