4.6 Article

Enhancing metabolite coverage in MALDI-MSI using laser post-ionisation (MALDI-2)

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ANALYTICAL METHODS
卷 -, 期 -, 页码 -

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d3ay01046e

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Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) coupled with laser post-ionisation (MALDI-2) has been used to image low molecular weight (LMW) metabolites, revealing alterations in metabolism throughout heterogeneous tissues.
Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) of metabolites can reveal how metabolism is altered throughout heterogeneous tissues. Here negative ion mode MALDI-MSI has been coupled with laser post-ionisation (MALDI-2) and applied to the MSI of low molecular weight (LMW) metabolites (

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