期刊
RSC ADVANCES
卷 6, 期 45, 页码 39401-39408出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra02029a
关键词
-
资金
- Shandong Provincial Natural Science Foundation, China [ZR2012BL11]
- Shandong Provincial Science and Technology Development Plan Project, China [2013GGX10705]
A facile electrochemical aptasensor based on a novel signal amplification strategy was employed for sensitive and selective detection of streptomycin for the first time. The aptasensor was prepared by sequentially dripping a gold nanoparticle-functionalized magnetic multi-walled carbon nanotube (Au@MWCNTs-Fe3O4) composite and nanoporous PtTi (NP-PtTi) alloy onto a glassy carbon electrode (GCE) surface. The NP-PtTi alloy with a uniform nanoporous structure was successfully fabricated by selectively de-alloying Al from a PtTiAl alloy in HCl solution. The results demonstrated that the Au@MWCNTs-Fe3O4/NP-PtTi composite not only showed a remarkable synergistic effect towards the aptasensor, but also provided a beneficial immobilization platform for the streptomycin aptamer carrier. Under optimal conditions, a wide linear range from 0.05 to 100 ng mL(-1) and a detection limit of 7.8 pg mL(-1) were obtained. The designed aptasensor showed an excellent analytical performance with good reproducibility, high selectivity and stability. Finally, the proposed aptasensor was successfully used for the detection of streptomycin in a real sample.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据