4.6 Article

A sensitive polymeric dark quencher-based sensing platform for fluorescence turn on detection of proteins

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RSC ADVANCES
卷 6, 期 48, 页码 42443-42446

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra07310g

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资金

  1. Natural Science Foundation of China [21572115, 21302108]
  2. Shenzhen Municipal Government [CXB201104210014A, 20150113A0410006]
  3. Shenzhen Reform Commission (Disciplinary Development Program for Chemical Biology)

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A fluorescence turn on detection platform for proteins has been developed with high sensitivity and specificity by taking advantage of highly efficient quenching of conjugated polymeric dark quenchers, as well as specific target recognition by either aptamer or peptide substrate probes.

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