期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 252, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2023.126205
关键词
Shrimp shell waste; Chitosan; Silver nanoparticle
The use of marine waste-derived chitosan (CS) for the synthesis of nanomaterials is effective for bio-waste management and recovering functional products. CS capped silver nanoparticles (Ag NPs-CS) were synthesized using shrimp shell waste and exhibited potential anticancer and dye pollutants adoption properties. The CS-Ag NPs showed anticancer activity against human lung adenocarcinoma cell lines and degradation of mixed dye target solution, suggesting their potential biomedical and environmental applications.
The use of marine waste derived chitosan (CS) for the synthesis of nanomaterials is considered as one of the effective routes for bio-waste management and recovering functional products. Herein, CS capped silver nano particles (Ag NPs-CS) with potential anticancer and dye pollutants adoption properties have been synthesized photochemically under direct sunlight. To obtain, CS, shrimp shell waste was subjected to a serious of standard demineralization, deproteinization and deacetylation processes. The electronic absorption peak (400 nm) denoting surface plasmonic resonance of Ag NPs and infrared peaks relevant to CS (3364 cm-1 of OH/NH2, 2932 cm-1 of CH, and 1647 cm-1 of-CO) exhibited peaks confirmed the formation of CS-Ag NPs. Ag NPs-CS exhibited anticancer activity against Human lung adenocarcinoma cell lines (A549), the maximum cell death noticed at the concentration of 20 & mu;g/mL and 70 & mu;g/mL was 20 and 52 %, respectively. An aqueous Ag NPs-CS (100 & mu;g/mL) was degraded & GE;95 % of mixed dye target solution (25 mg/mL) containing equal volume of cationic dye (Methylene blue and Rhodamine B) and anionic dye (methyl orange). Therefore, these findings suggest that the shrimp shell waste derived CS can be used for the synthesis of CS-Ag NPs with potential biomedical and environmental applications.
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