4.6 Article

Self-propelled manganese oxide-based catalytic micromotors for drug delivery

期刊

RSC ADVANCES
卷 6, 期 70, 页码 65624-65630

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c6ra13739c

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资金

  1. Ministry of Education of China [IRT1148]
  2. NSFC [20905038, 61504066]
  3. Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM)
  4. Synergistic Innovation Center for Organic Electronics and Information Displays
  5. Jiangsu Province Six Talent Peak [2015-JY-015]
  6. Jiangsu Provincial NSF [BK20141424, BK20150838]
  7. NUPT [NY214088]
  8. State Key Laboratory of Bioelectronics, Southeast University [I2015010]

向作者/读者索取更多资源

A manganese oxide-based catalytic tubular micromotor (PEDOT/ MnO2) is described that displays effective autonomous motion in hydrogen peroxide with high speed (318.80 mu ms(-1)) and can operate in very low levels of fuel, down to 0.4%. The polymer bilayer micromotor also exhibits efficient locomotion in different biological media including bovine serum albumin and bovine serum. Moreover, the micromotor is applied to deliver a chemotherapeutic anticancer drug, camptothecin, using electrostatic interactions, offering considerable potential for diverse clinical and biomedical applications such as drug delivery for theranostic microsystems.

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