Highly selective intramolecular addition of C-N and S-N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles

Palladium-catalyzed highly selective intramolecular addition of C-N and S-N bonds to alkynes has been achieved, and two distinct functional indoles were synthesized rapidly from the same set of substrates in a catalyst-controlled manner. This protocol features high atom economy, moderate to high yields and excellent selectivity, thus affording a practical approach to functional indoles.