期刊
CLINICAL NUTRITION
卷 34, 期 5, 页码 892-898出版社
CHURCHILL LIVINGSTONE
DOI: 10.1016/j.clnu.2014.09.012
关键词
25(OH)D; Vitamin D intake; Vitamin D status; Pregnancy; Obesity; Supplement use
资金
- Novo Nordisk Foundation
- Swedish Research Council [12206]
- Swedish Diabetes Association Research Foundation
- Swedish federal government under the LUA/ALF agreement
- IngaBritt and Arne Lundbergs Foundation
- Freemasonry Children's house Board in Gothenburg
- Swedish Nutrition Foundation
- Wilhelm and Martina Lundgren Foundation
Background: Obesity is associated with lower vitamin D concentrations than normal-weight. Pregnancy may affect vitamin D status, especially in obese subjects. Aims: The purpose of this study was to compare vitamin D status and intake between obese and normal-weight women during pregnancy. Methods: Twenty-five obese and 80 normal-weight women were recruited in the Western Sweden region (latitude 57 degrees N). Blood samples and information on diet and sun exposure were collected in each trimester during pregnancy. Results: During summer months, 12% of normal-weight and 50% of obese women in the first trimester had serum 25(OH)D concentrations <50 nmol/L (P < 0.01). Supplement use, body fat mass, season of blood sampling, and travelling to southern latitudes were the most important determinants of vitamin D status. Obese women had higher reported dietary vitamin D intake in early pregnancy compared with normal-weight women. Usage of supplements containing vitamin D was 61% in early pregnancy and declined thereafter. Nine percent of normal-weight and 33% of obese women (P < 0.01) reported a dietary vitamin D intake according to national recommendations in the beginning of pregnancy. Conclusions: Half of the obese women had what could be considered as suboptimal vitamin D status in early pregnancy and lower vitamin D status compared with normal-weight women despite reporting a higher dietary vitamin D intake. A majority of the women did not reach intake of vitamin D according to dietary recommendations. (C) 2014 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
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