期刊
NUTRIENTS
卷 8, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/nu8060361
关键词
isoflavones; anti-inflammation; health risks; flavonoids
资金
- National Science & Technology Pillar Program [2014BAD13B01]
- Key Project in Sichuan Science & Technology Pillar Program [2013NZ0056]
Inflammation, a biological response of body tissues to harmful stimuli, is also known to be involved in a host of diseases, such as obesity, atherosclerosis, rheumatoid arthritis, and even cancer. Isoflavones are a class of flavonoids that exhibit antioxidant, anticancer, antimicrobial, and anti-inflammatory properties. Increasing evidence has highlighted the potential for isoflavones to prevent the chronic diseases in which inflammation plays a key role, though the underlying mechanisms remain unclear. Recently, some studies have raised concerns about isoflavones induced negative effects like carcinogenesis, thymic involution, and immunosuppression. Therefore, this review aims to summarize the anti-inflammatory effects of isoflavones, unravel the underlying mechanisms, and present the potential health risks.
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