相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Dynamics of the Ligand Binding Domain Layer during AMPA Receptor Activation
Jelena Baranovic et al.
BIOPHYSICAL JOURNAL (2016)
Superactivation of AMPA receptors by auxiliary proteins
Anna L. Carbone et al.
NATURE COMMUNICATIONS (2016)
Probing Intersubunit Interfaces in AMPA-subtype Ionotropic Glutamate Receptors
Maria V. Yelshanskaya et al.
SCIENTIFIC REPORTS (2016)
Dose-Response Analysis When There Is a Correlation between Affinity and Efficacy
Anthony Auerbach
MOLECULAR PHARMACOLOGY (2016)
The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold
Giovanni Gonzalez-Gutierrez et al.
JOURNAL OF GENERAL PHYSIOLOGY (2015)
Crystal structure of human glycine receptor-α3 bound to antagonist strychnine
Xin Huang et al.
NATURE (2015)
Glycine receptor mechanism elucidated by electron cryo-microscopy
Juan Du et al.
NATURE (2015)
Physical basis of apparent pore dilation of ATP-activated P2X receptor channels
Mufeng Li et al.
NATURE NEUROSCIENCE (2015)
Glycine activated ion channel subunits encoded by ctenophore glutamate receptor genes
Robert Alberstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor
Radovan Spurny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Convergence of ion channel genome content in early animal evolution
Benjamin J. Liebeskind et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
The desensitization gate of inhibitory Cys-loop receptors
Marc Gielen et al.
NATURE COMMUNICATIONS (2015)
Stoichiometry for α-bungarotoxin block of α7 acetylcholine receptors
Corrie J. B. daCosta et al.
NATURE COMMUNICATIONS (2015)
Catch-and-Hold Activation of Muscle Acetylcholine Receptors Having Transmitter Binding Site Mutations
Prasad Purohit et al.
BIOPHYSICAL JOURNAL (2014)
Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States
Katharina L. Duerr et al.
CELL (2014)
Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors
Wei Zhang et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2014)
Lynx1 Shifts α4β2 Nicotinic Receptor Subunit Stoichiometry by Affecting Assembly in the Endoplasmic Reticulum
Weston A. Nichols et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Crystal structure of a human GABAA receptor
Paul S. Miller et al.
NATURE (2014)
X-ray structure of the mouse serotonin 5-HT3 receptor
Gherici Hassaine et al.
NATURE (2014)
Structural mechanism of glutamate receptor activation and desensitization
Joel R. Meyerson et al.
NATURE (2014)
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
Thorsten Althoff et al.
NATURE (2014)
NMDA receptor structures reveal subunit arrangement and pore architecture
Chia-Hsueh Lee et al.
NATURE (2014)
Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents
Rashek Kazi et al.
NATURE NEUROSCIENCE (2014)
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation
Ludovic Sauguet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structure of an agonist-bound ionotropic glutamate receptor
Maria V. Yelshanskaya et al.
SCIENCE (2014)
The new frontier of genome engineering with CRISPR-Cas9
Jennifer A. Doudna et al.
SCIENCE (2014)
X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism
Lei Chen et al.
SCIENCE (2014)
Crystal structure of a heterotetrameric NMDA receptor ion channel
Erkan Karakas et al.
SCIENCE (2014)
Radial symmetry in a chimeric glutamate receptor pore
Timothy J. Wilding et al.
NATURE COMMUNICATIONS (2014)
Loop C and the mechanism of acetylcholine receptor-channel gating
Prasad Purohit et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
A propofol binding site on mammalian GABAA receptors identified by photolabeling
Grace M. S. Yip et al.
NATURE CHEMICAL BIOLOGY (2013)
Defining the structural relationship between kainate-receptor deactivation and desensitization
G. Brent Dawe et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
A Conformational Intermediate in Glutamate Receptor Activation
Albert Y. Lau et al.
NEURON (2013)
Nanoscale Scaffolding Domains within the Postsynaptic Density Concentrate Synaptic AMPA Receptors
Harold D. MacGillavry et al.
NEURON (2013)
Functional anatomy of an allosteric protein
Prasad Purohit et al.
NATURE COMMUNICATIONS (2013)
Site-Directed Spin Labeling Reveals Pentameric Ligand-Gated Ion Channel Gating Motions
Cosma D. Dellisanti et al.
PLOS BIOLOGY (2013)
Benzodiazepines Modulate GABAA Receptors by Regulating the Preactivation Step after GABA Binding
Marc C. Gielen et al.
JOURNAL OF NEUROSCIENCE (2012)
The α1K276E Startle Disease Mutation Reveals Multiple Intermediate States in the Gating of Glycine Receptors
Remigijus Lape et al.
JOURNAL OF NEUROSCIENCE (2012)
Amino-Terminal Ligands Prolong NMDA Receptor-Mediated EPSCs
Kenneth R. Tovar et al.
JOURNAL OF NEUROSCIENCE (2012)
Coupled Control of Desensitization and Gating by the Ligand Binding Domain of Glutamate Receptors
Anna L. Carbone et al.
NEURON (2012)
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines
Radovan Spurny et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine
Jianjun Pan et al.
NATURE COMMUNICATIONS (2012)
Mechanism of AMPA Receptor Activation by Partial Agonists DISULFIDE TRAPPING OF CLOSED LOBE CONFORMATIONS
Ahmed H. Ahmed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Single-Channel and Structural Foundations of Neuronal α7 Acetylcholine Receptor Potentiation
Corrie J. B. daCosta et al.
JOURNAL OF NEUROSCIENCE (2011)
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Hugues Nury et al.
NATURE (2011)
Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
Erkan Karakas et al.
NATURE (2011)
Principles of activation and permeation in an anion-selective Cys-loop receptor
Ryan E. Hibbs et al.
NATURE (2011)
Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist
Shu-Xing Li et al.
NATURE NEUROSCIENCE (2011)
The hidden energetics of ligand binding and activation in a glutamate receptor
Albert Y. Lau et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Specific Sites within the Ligand-Binding Domain and Ion Channel Linkers Modulate NMDA Receptor Gating
Iehab Talukder et al.
JOURNAL OF NEUROSCIENCE (2010)
Domain organization and function in GluK2 subtype kainate receptors
Utpal Das et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Variant Ionotropic Glutamate Receptors as Chemosensory Receptors in Drosophila
Richard Benton et al.
CELL (2009)
Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors
Diego Rayes et al.
JOURNAL OF NEUROSCIENCE (2009)
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE (2009)
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
Nicolas Bocquet et al.
NATURE (2009)
Mechanism of differential control of NMDA receptor activity by NR2 subunits
Marc Gielen et al.
NATURE (2009)
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
Alexander I. Sobolevsky et al.
NATURE (2009)
Crystal structure of the ATP-gated P2X4 ion channel in the closed state
Toshimitsu Kawate et al.
NATURE (2009)
Detection and trapping of intermediate states priming nicotinic receptor channel opening
Nuriya Mukhtasimova et al.
NATURE (2009)
Kinetic basis of partial agonism at NMDA receptors
Cassandra L. Kussius et al.
NATURE NEUROSCIENCE (2009)
High-resolution structure of the open NaK channel
Amer Alam et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE (2008)
Distinct gating modes determine the biphasic relaxation of NMDA receptor currents
Wei Zhang et al.
NATURE NEUROSCIENCE (2008)
Molecular basis of kainate receptor modulation by sodium
Andrew J. R. Plested et al.
NEURON (2008)
A domain linking the AMPA receptor agonist binding site to the ion pore controls Gating and causes lurcher properties when mutated
Sabine M. Schmid et al.
JOURNAL OF NEUROSCIENCE (2007)
Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH
Jayasankar Jasti et al.
NATURE (2007)
Conformational restriction blocks glutamate receptor desensitization
Matthew C. Weston et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites
Alastair M. Hosie et al.
NATURE (2006)
Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog
Guo-Dong Li et al.
JOURNAL OF NEUROSCIENCE (2006)
Functional properties of spontaneous IPSCs and glycine receptors in rod amacrine (AII) cells in the rat retina
Silje Bakken Gill et al.
JOURNAL OF PHYSIOLOGY-LONDON (2006)
Glutamate-based therapeutic approaches: ampakines
G Lynch
CURRENT OPINION IN PHARMACOLOGY (2006)
Probing ion-channel pores one proton at a time
GD Cymes et al.
NATURE (2005)
Maximum likelihood fitting of single channel NMDA activity with a mechanism composed of independent dimers of subunits
S Schorge et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
WY Lee et al.
NATURE (2005)
Evolution of glutamate interactions during binding to a glutamate receptor
Q Cheng et al.
NATURE CHEMICAL BIOLOGY (2005)
Molecular mechanism of AMPA receptor noncompetitive antagonism
V Balannik et al.
NEURON (2005)
Mechanism of partial agonist action at the NR1 subunit of NMDA receptors
A Inanobe et al.
NEURON (2005)
Stargazin modulates AMPA receptor gating and trafficking by distinct domains
S Tomita et al.
NATURE (2005)
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors
Y Bourne et al.
EMBO JOURNAL (2005)
AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization
A Robert et al.
JOURNAL OF NEUROSCIENCE (2005)
The outer pore of the glutamate receptor channel has 2-fold rotational symmetry
AI Sobolevsky et al.
NEURON (2004)
The activation mechanism of α1 homomeric glycine receptors
M Beato et al.
JOURNAL OF NEUROSCIENCE (2004)
Single-channel behavior of heteromeric α1β glycine receptors:: An attempt to detect a conformational change before the channel opens
V Burzomato et al.
JOURNAL OF NEUROSCIENCE (2004)
Effects of the lurcher mutation on GluR1 desensitization and activation kinetics
RM Klein et al.
JOURNAL OF NEUROSCIENCE (2004)
Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain
MV Yelshansky et al.
JOURNAL OF NEUROSCIENCE (2004)
Properties of quantal transmission at CA1 synapses
S Raghavachari et al.
JOURNAL OF NEUROPHYSIOLOGY (2004)
UCSF chimera - A visualization system for exploratory research and analysis
EF Pettersen et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2004)
Structural basis for partial agonist action at ionotropic glutamate receptors
RS Jin et al.
NATURE NEUROSCIENCE (2003)
Structure and gating mechanism of the acetylcholine receptor pore
A Miyazawa et al.
NATURE (2003)
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
H Furukawa et al.
EMBO JOURNAL (2003)
Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate
RS Jin et al.
BIOCHEMISTRY (2002)
Desensitization of diliganded mouse muscle nicotinic acetylcholine receptor channels
S Elenes et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Mechanism of glutamate receptor desensitization
Y Sun et al.
NATURE (2002)
Emerging structure of the nicotinic acetylcholine receptors
A Karlin
NATURE REVIEWS NEUROSCIENCE (2002)
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
K Brejc et al.
NATURE (2001)
Agonist-induced isomerization in a glutamate receptor ligand-binding domain -: A kinetic and mutagenetic analysis
R Abele et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Mapping the conformational wave of acetylcholine receptor channel gating
C Grosman et al.
NATURE (2000)
分享论文
