期刊
MAGNETIC RESONANCE IN MEDICAL SCIENCES
卷 15, 期 4, 页码 365-370出版社
JPN SOC MAGNETIC RESONANCE MEDICINE
DOI: 10.2463/mrms.mp.2015-0107
关键词
atlas-based method; brain volumetry; low static magnetic field; repeatability; WFU PickAtlas
资金
- Ministry of Health, Labor and Welfare, Japan
Purpose: An understanding of the repeatability of measured results is important for both the atlas-based and voxel-based morphometry (VBM) methods of magnetic resonance (MR) brain volumetry. However, many recent studies that have investigated the repeatability of brain volume measurements have been perfouned using static magnetic fields of 1-4 tesla, and no study has used a low-strength static magnetic field. The aim of this study was to investigate the repeatability of measured volumes using the atlas-based method and a low-strength static magnetic field (0.4 tesla). Materials and Methods: Ten healthy volunteers participated in this study. Using a 0.4 tesla magnetic resonance imaging (MRI) scanner and a quadrature head coil, three-dimensional T-1-weighted images (3D-T(1)WIs) were obtained from each subject, twice on the same day. VBM8 software was used to construct segmented normalized images [gray matter (GM), white matter (WM), and cerebrospinal fluid (CSF) images]. The regions-of-interest (ROIs) of GM, WM, CSF, hippocampus (HC), orbital gyms (OG), and cerebellum posterior lobe (CPL) were generated using WFU PickAtlas. The percentage change was defined as [100 x (measured volume with first segmented image - mean volume in each subject)/(mean volume in each subject)] The average percentage change was calculated as the percentage change in the 6 ROIs of the 10 subjects. Results: The mean of the average percentage changes for each ROI was as follows: GM, 0.556%; WM, 0.324%; CSF, 0.573%; HC, 0.645%; OG, 1.74%; and CPL, 0.471%. The average percentage change was higher for the orbital gyms than for the other ROIs. Conclusion: We consider that repeatability of the atlas-based method is similar between 0.4 and 1.5 tesla MR scanners. To our knowledge, this is the first report to show that the level of repeatability with a 0.4 tesla MR scanner is adequate for the estimation of brain volume change by the atlas-based method.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据