期刊
BIOMEDICAL OPTICS EXPRESS
卷 7, 期 8, 页码 2943-2954出版社
OPTICAL SOC AMER
DOI: 10.1364/BOE.7.002943
关键词
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资金
- Oregon Health & Science Foundation
- National Institutes of Health Grants [DP3 DK104397, R01 EY024544, R01 EY023285, R01 EY018184]
- Research to Prevent Blindness (New York, NY)
- National Institutes of Health (Bethesda, MD) [P30 EY010572]
A phase gradient angiography (PGA) method is proposed for optical coherence tomography (OCT). This method allows the use of phase information to map the microvasculature in tissue without the correction of bulk motion and laser trigger jitter induced phase artifacts. PGA can also be combined with the amplitude/intensity to improve the performance. Split-spectrum technique can further increase the signal to noise ratio by more than two times. In-vivo imaging of human retinal circulation is shown with a 70 kHz, 840 nm spectral domain OCT system and a 200 kHz, 1050 nm swept source OCT system. Four different OCT angiography methods are compared. The best performance was achieved with split-spectrum amplitude and phase-gradient angiography. (C) 2016 Optical Society of America
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