A sensitive and selective spectrophotometric method for 2-chlorophenol based on solid phase extraction with mixed hemimicelle magnetic nanoparticles

The first study of a sensitive and selective spectrophotometric detection of 2-chlorophenol (2-CP) was reported. The method is based on derivatization of 2-CP with 4-aminoantipyrine (4-AAP) and subsequent preconcentration by solid phase extraction (SPE) using mixed hemimicelles adsorbent of cetyltrimethylammonium bromide coated magnetic nanoparticles (CTAB coated Fe3O4 NPs) before its detection by spectrophotometry at 510 nm. The adsorption capacity was evaluated using the Langmuir adsorption isotherm model, with high correlation coefficients (R-2 = 0.9983). The optimum conditions for SPE were CTAB coated Fe3O4 NPs 20 mg under vortex 60 s and methanol as the desorption solvent under sonication for 7 min. The linearity of the method was in the range of 0.05-1.0 mg L-1 with correlation coefficient (0.9970). The limit of detection (LOD) and limit of quantitation (LOQ) were 0.01 mg L-1 and 0.05 mg L-1, respectively. Good precision with relative standard deviation (%RSD, n = 5) less than 3.7% was obtained. The method was successfully applied for the determination of 2-CP in soil samples with satisfactory recoveries (81.7-95.2%). (C) 2015 Production and hosting by Elsevier B.V. on behalf of King Saud University.