期刊
ACS CATALYSIS
卷 6, 期 11, 页码 7303-7310出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.6b02561
关键词
PdPb; decarboxylation; L-proline; pyrrolidine; biobased amine; water
资金
- Fonds Wetenschappelijk Onderzoek (FWO)
- Agency for Innovation by Science and Technology (IWT)
- IWT
- FWO
- Flemish government through Methusalem
- Belspo [IAP-PAI 7/05]
- European Research Council (ERC) [335078-COLOURATOMS]
Amino acids have huge potential as platform chemicals in the biobased industry. Pd-catalyzed decarboxylation is a very promising route for the valorization of these natural compounds derived from protein waste or fermentation. We report that the highly abundant and nonessential amino acid L-proline is very reactive in the Pd-catalyzed decarboxylation. Full conversions are obtained with Pd/C and different Pd/MeOx catalysts; this allowed the identification of the different side reactions and the mapping of the reaction network. Due to the high reactivity of pyrrolidine, the selectivity for pyrrolidine was initially low. By carefully modifying Pd/ZrO2 with Pb in a controlled manner-via two incipient wetness impregnation steps-the selectivity increased remarkably. Finally, a thorough investigation of the reaction parameters resulted in an increased activity of this modified catalyst and an even further enhanced selectivity under a low H-2 pressure of 4 bar at 235 degrees C in water. This results in a very selective and sustainable production route for the highly interesting pyrrolidine.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据