相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair
Takashi Ochi et al.
SCIENCE (2015)
PTH1-34 Blocks Radiation-induced Osteoblast Apoptosis by Enhancing DNA Repair through Canonical Wnt Pathway
Abhishek Chandra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration
Ciara Metcalfe et al.
CELL STEM CELL (2014)
Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time
Gareth J. Williams et al.
DNA REPAIR (2014)
Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration
William Lento et al.
GENES & DEVELOPMENT (2014)
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
Kerstin Felgentreff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
Hans Clevers et al.
SCIENCE (2014)
Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage
Ludovic Deriano et al.
ANNUAL REVIEW OF GENETICS, VOL 47 (2013)
The Intestinal Crypt, A Prototype Stem Cell Compartment
Hans Clevers
CELL (2013)
A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors
K. Tilgner et al.
CELL DEATH AND DIFFERENTIATION (2013)
MicroRNA-324-3p regulates nasopharyngeal carcinoma radioresistance by directly targeting WNT2B
Guo Li et al.
EUROPEAN JOURNAL OF CANCER (2013)
Dyrk2-associated EDD-DDB1-VprBP E3 Ligase Inhibits Telomerase by TERT Degradation
Hae-Yun Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
PAF and EZH2 Induce Wnt/β-Catenin Signaling Hyperactivation
Hae-Yun Jung et al.
MOLECULAR CELL (2013)
Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection
Wei-Jie Zhou et al.
NATURE (2013)
A colorectal cancer classification system that associates cellular phenotype and responses to therapy
Anguraj Sadanandam et al.
NATURE MEDICINE (2013)
Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction
Sehyun Oh et al.
NUCLEIC ACIDS RESEARCH (2013)
PAF-Mediated MAPK Signaling Hyperactivation via LAMTOR3 Induces Pancreatic Tumorigenesis
Sohee Jun et al.
CELL REPORTS (2013)
An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression
Mrinal Srivastava et al.
CELL (2012)
Wnt/β-Catenin Signaling and Disease
Hans Clevers et al.
CELL (2012)
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
Javier Munoz et al.
EMBO JOURNAL (2012)
Concurrent Transient Activation of Wnt/β-Catenin Pathway Prevents Radiation Damage to Salivary Glands
Bo Hai et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)
Wnt activation is implicated in glioblastoma radioresistance
Yonghyun Kim et al.
LABORATORY INVESTIGATION (2012)
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
Kelley S. Yan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels
Elisia D. Tichy et al.
STEM CELL RESEARCH (2012)
Wnt Signaling in Cancer
Paul Polakis
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Identification of differentially expressed genes related to radioresistance of human esophageal cancer cells
Hong-Zhen Li et al.
Chinese Journal of Cancer (2012)
Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy
Emil Kendziorra et al.
CARCINOGENESIS (2011)
Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients
Felipe de Sousa e Melo et al.
CELL STEM CELL (2011)
Targeting Wnt Signaling in Colon Cancer Stem Cells
E. Melo Felipe de Sousa et al.
CLINICAL CANCER RESEARCH (2011)
The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells
S. -M. Che et al.
DISEASES OF THE ESOPHAGUS (2011)
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
Hua Tian et al.
NATURE (2011)
Response of normal stem cells to ionizing radiation: A balance between homeostasis and genomic stability
Ghida Harfouche et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Lentiviral Vectors to Probe and Manipulate the Wnt Signaling Pathway
Christophe Fuerer et al.
PLOS ONE (2010)
Selective targeting of radiation-resistant tumor-initiating cells
Mei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Senescence evasion by MCF-7 human breast tumor-initiating cells
Feridoun Karimi-Busheri et al.
BREAST CANCER RESEARCH (2010)
Telomerase modulates Wnt signalling by association with target gene chromatin
Jae-Il Park et al.
NATURE (2009)
The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
NATURE (2009)
Protective Role of R-spondin1, an Intestinal Stem Cell Growth Factor, against Radiation-Induced Gastrointestinal Syndrome in Mice
Payel Bhanja et al.
PLOS ONE (2009)
R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway
Jingsong Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies
Sonya D. Zabludoff et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Wnt signaling controls radiosensitivity via cyclooxygenase-2-mediated Ku expression in head and neck cancer
Hyo Won Chang et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
DNA repair is limiting for haematopoietic stem cells during ageing
Anastasia Nijnik et al.
NATURE (2007)
Wnt/β-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line
Mercy S. Chen et al.
JOURNAL OF CELL SCIENCE (2007)
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
Wendy A. Woodward et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells
Y Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency
M O'Driscoll et al.
MOLECULAR CELL (2001)
Homologous DNA recombination in vertebrate cells
E Sonoda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
KM Frank et al.
MOLECULAR CELL (2000)
Mouse mutants from chemically mutagenized embryonic stem cells
RJ Munroe et al.
NATURE GENETICS (2000)