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J. Ross Chapman et al.
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Fei Huang et al.
ACS CHEMICAL BIOLOGY (2011)
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Pietro Pichierri et al.
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WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes
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Xuefeng Chen et al.
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Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks
Shuren Liao et al.
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Roles of Werner syndrome protein in protection of genome integrity
Marie L. Rossi et al.
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ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
Francesca Ammazzalorso et al.
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Saccharomyces cerevisiae Mre11/Rad50/Xrs2 and Ku proteins regulate association of Exo1 and Dna2 with DNA breaks
Eun Yong Shim et al.
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Pathways of mammalian replication fork restart
Eva Petermann et al.
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Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
Pablo Huertas et al.
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The DNA-damage response in human biology and disease
Stephen P. Jackson et al.
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Mechanism of eukaryotic homologous recombination
Joseph San Filippo et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
Julia M. Sidorova et al.
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Roles of the Werner syndrome RecQ helicase in DNA replication
Julia M. Sidorova
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Comparison of nonhomologous end joining and homologous recombination in human cells
Zhiyong Mao et al.
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Livia Maria Pirzio et al.
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Aude Dupre et al.
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An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
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DNA double-strand break repair and chromosome translocations
Sheba Agarwal et al.
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Functions of human replication protein A (RPA): From DNA replication to DNA damage and stress responses
Yue Zou et al.
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Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair
H Yan et al.
JOURNAL OF CELL BIOLOGY (2005)
Werner syndrome protein and the MRE11 complex are involved in a common pathway of replication fork recovery
A Franchitto et al.
CELL CYCLE (2004)
Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of Werner syndrome protein
S Choudhary et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1
WH Cheng et al.
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Mechanism and regulation of human non-homologous DNA end-joining
MR Lieber et al.
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Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle
P Pichierri et al.
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Asymmetry of DNA replication fork progression in Werner's syndrome
AM Rodríguez-López et al.
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Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation
P Karmakar et al.
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Protein detection using proximity-dependent DNA ligation assays
S Fredriksson et al.
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Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
AJ Pierce et al.
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Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle
P Pichierri et al.
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Evidence that camptothecin-induced aberrations in the G2 phase of cell cycle of Chinese hamster ovary (CHO) cell lines is associated with transcription
P Mosesso et al.
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Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms
S Lambert et al.
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Werner's syndrome lymphoblastoid cells are hypersensitive to topoisomerase II inhibitors in the G2 phase of the cell cycle
P Pichierri et al.
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