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Hamed S. Najafabadi et al.
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Yuyu Niu et al.
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Chunliang Li et al.
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Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
Yanfang Fu et al.
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Dimeric CRISPR RNA-guided Fokl nucleases for highly specific genome editing
Shengdar Q. Tsai et al.
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Fusion of catalytically inactive Cas9 to Fokl nuclease improves the specificity of genome modification
John P. Guilinger et al.
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John P. Guilinger et al.
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E-CRISP: fast CRISPR target site identification
Florian Heigwer et al.
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A guide to genome engineering with programmable nucleases
Hyongbum Kim et al.
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Anton V. Persikov et al.
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CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing
Tessa G. Montague et al.
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David J. Segal et al.
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TALENoffer: genome-wide TALEN off-target prediction
Jan Grau et al.
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Ning Sun et al.
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F. Ann Ran et al.
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Scott J. Gratz et al.
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Highly active zinc-finger nucleases by extended modular assembly
Mital S. Bhakta et al.
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Metewo Selase Enuameh et al.
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DNA targeting specificity of RNA-guided Cas9 nucleases
Patrick D. Hsu et al.
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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu et al.
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Heritable genome editing in C. elegans via a CRISPR-Cas9 system
Ari E. Friedland et al.
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Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
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David Bikard et al.
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RNA-Guided Human Genome Engineering via Cas9
Prashant Mali et al.
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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
Thomas Gaj et al.
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Stephanie W. Chu et al.
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Douglas M. Anderson et al.
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An optimized two-finger archive for ZFN-mediated gene targeting
Ankit Gupta et al.
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Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains
Le Cong et al.
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A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
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An unbiased genome-wide analysis of zinc-finger nuclease specificity
Richard Gabriel et al.
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Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
Vikram Pattanayak et al.
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FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system
Lihua Julie Zhu et al.
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A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
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An expanded binding model for Cys2His2 zinc finger protein-DNA interfaces
Anton V. Persikov et al.
PHYSICAL BIOLOGY (2011)
Genome editing with engineered zinc finger nucleases
Fyodor D. Urnov et al.
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Leping Li
JOURNAL OF COMPUTATIONAL BIOLOGY (2009)
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
Dirk Hockemeyer et al.
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Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites
Marcus B. Noyes et al.
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Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification
Morgan L. Maeder et al.
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Comparison of zinc finger nucleases for use in gene targeting in mammalian cells
Shondra M. Pruett-Miller et al.
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Elena E. Perez et al.
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Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
Xiangdong Meng et al.
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Unexpected failure rates for modular assembly of engineered zinc fingers
Cherie L. Ramirez et al.
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High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR)
Schmidt Manfred et al.
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An improved zinc-finger nuclease architecture for highly specific genome editing
Jeffrey C. Miller et al.
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A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors
XD Meng et al.
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Rearrangement of side-chains in a zif268 mutant highlights the complexities of zinc finger-DNA recognition
JC Miller et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions
JK Joung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)