期刊
HPB
卷 18, 期 11, 页码 879-885出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.hpb.2016.06.007
关键词
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资金
- MRC [MR/P001483/1] Funding Source: UKRI
- Medical Research Council [MR/P001483/1] Funding Source: researchfish
- National Institute for Health Research [ACF-2012-02-007] Funding Source: researchfish
- Medical Research Council [MR/P001483/1] Funding Source: Medline
Introduction: Side branch IPMN (SB-IPMN) of the pancreas has a malignancy rate between 10 and 20%. We hypothesized that surveillance at longer intervals on selected patients with SB-IPMN might be indicated. Methods: This is a retrospective study of prospectively collected data of 276 patients presenting from 2000 to 2010. After 2007, we opted to screen our patients with longer intervals, initially at 12 months then 24 months using MR if no worrisome features were present. Results: Complete data sets for 261 patients were analysed and patients were aged 78 (40-91) years. 232 patients had sole SB-IPMN while 92% were incidental (n = 209) and 8% were symptomatic (n = 24). Single SB-IPMN accounted for 84% (n = 195) of all cases; maximum diameter of 15.5 (5-60) mm. The median follow up duration was 46 (32-53) months. Short interval radiological surveillance (3-9 months) was 39% (n = 90), while long interval surveillance (12-36 months) was performed in 61% (n = 142). The rate of pancreatic resection, due to concern for the development of pancreatic cancer, in the short and long interval surveillance groups was 4.4% (n = 4) and 3.5% (n = 5) respectively; p = 0.78. Conclusion: Our data suggests no difference in outcome between long and short interval MR surveillance of SB-IPMN patients.
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