期刊
MEDCHEMCOMM
卷 7, 期 1, 页码 28-36出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5md00351b
关键词
-
资金
- National Institutes of Health [PO1GM077596]
Research studies in recent years have illuminated data on the mechanisms and targets of phosphonic acid antibiotics and herbicides, including fosfomycin, glyphosate, fosmidomycin and FR900098. Here we review the current state of knowledge of the structural and biochemical characterization of resistance mechanisms against these bioactive natural products. Advances in the understanding of these resistance determinants have spurred knowledge-based campaigns aimed at the design of derivatives that retain biological activity but are less prone to tolerance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据