期刊
CLINICAL INFECTIOUS DISEASES
卷 61, 期 4, 页码 619-622出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/civ386
关键词
innate immunity; SNP; PTX3; genetic susceptibility; solid organ transplant
资金
- Swiss National Foundation [324730-144054]
- Leenaards Foundation
- San-tos-Suarez Foundation
- Loterie Romande
- Merieux Research Grant
- European Union's Seventh Framework Program (ALLFUN) [HEALTH-2010-260338]
- STCS [12]
- Emma Muschamp Foundation
- FLTO Foundation (Fondation Lausannoise pour la transplantation d'organes)
- Swiss National Research Foundation [33CS30_148512]
- Swiss National Science Foundation (SNF) [324730_144054, 33CS30_148512] Funding Source: Swiss National Science Foundation (SNF)
Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infections among 1101 solid organ transplant recipients, thereby strengthening their role in mold infection pathogenesis and patients' risk stratification.
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