期刊
CLINICAL INFECTIOUS DISEASES
卷 61, 期 -, 页码 S164-S172出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/civ613
关键词
tuberculosis; children; diagnosis; biomarker; blueprint
资金
- NIAID/NIH
- Eunice Kennedy Shriver NICHD
- US Department of Health and Human Services [HHSN272200800014C]
Childhood tuberculosis contributes significantly to the global tuberculosis disease burden but remains challenging to diagnose due to inadequate methods of pathogen detection in paucibacillary pediatric samples and lack of a child-specific host biomarker to identify disease. Accurately diagnosing tuberculosis in children is required to improve case detection, surveillance, healthcare delivery, and effective advocacy. In May 2014, the National Institutes of Health convened a workshop including researchers in the field to delineate priorities to address this research gap. This blueprint describes the consensus from the workshop, identifies critical research steps to advance this field, and aims to catalyze efforts toward harmonization and collaboration in this area.
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