期刊
WORLD JOURNAL OF GASTROENTEROLOGY
卷 22, 期 29, 页码 6610-6618出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.3748/wjg.v22.i29.6610
关键词
Noncoding RNAs; Gastric cancer; MicroRNA; Long ncRNAs; PIWI-interacting RNAs; Competing endogenous RNA
资金
- National Natural Science Foundation of China [81472220]
- Shanghai Science and Technology Development Fund, Domestic Science and Technology Cooperation Project [14495800300]
Noncoding RNAs (ncRNAs) have attracted much attention in cancer research field. They are involved in cellular development, proliferation, differentiation and apoptosis. The dysregulation of ncRNAs has been reported in tumor initiation, progression, invasion and metastasis in various cancers, including gastric cancer (GC). In the past few years, an accumulating body of evidence has deepened our understanding of ncRNAs, and several emerging ncRNAs have been identified, such as PIWI-interacting RNAs (piRNAs) and circular RNAs (circRNAs). The competing endogenous RNA (ceRNA) networks include mRNAs, microRNAs, long ncRNAs (lncRNAs) and circRNAs, which play critical roles in the tumorigenesis of GC. This review summarizes the recent hotspots of ncRNAs involved in GC pathobiology and their potential applications in GC. Finally, we briefly discuss the advances in the ceRNA network in GC.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据