期刊
TROPICAL DOCTOR
卷 47, 期 1, 页码 77-84出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0049475516644141
关键词
Vitamin D; lower respiratory tract infection (LRTI); cohort; case-control study
Studies related to vitamin D deficiency and lower respiratory tract infections (LRTI) in children have inconsistent findings. The objective of this systematic review was to assess the prevalence of vitamin D deficiency in children with LRTI, and to evaluate the correlation between vitamin D levels and the incidence and severity of LRTI. A total of 12 studies enrolling 2279 participants were included in our analysis. Children with LRTI were found to have significantly lower mean vitamin D levels as compared to controls There was likewise a correlation between vitamin D levels and incidence and severity of LRTI. Large randomised controlled trials are needed to evaluate effect of vitamin D supplementation for LRTI.
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