期刊
TRENDS IN MOLECULAR MEDICINE
卷 22, 期 4, 页码 271-273出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.molmed.2016.02.009
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资金
- NCI NIH HHS [P30 CA008748] Funding Source: Medline
T cells expressing chimeric antigen receptors (CARs) are a formidable platform for the study and application of synthetic biology approaches to study customized and flexible control of cellular functions. Recent reports in the journal Cell provide a new twist on combinatorial antigen targeting, profiting from the singular cleavage and signaling of the Notch receptor to conditionally express CARs.
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