期刊
TRENDS IN MICROBIOLOGY
卷 24, 期 5, 页码 377-390出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.tim.2016.03.001
关键词
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Bacterial survival necessitates endurance of many types of antimicrobial compound. Many Gram-negative envelope stress responses, which must contend with an outer membrane and a dense periplasm containing the cell wall, have been associated with the status of protein folding, membrane homeostasis, and physiological functions such as efflux and the proton motive force (PMF). In this review, we discuss evidence that indicates an emerging role for Gram-negative envelope stress responses in enduring exposure to diverse antimicrobial substances, focusing on recent studies of the gamma-proteobacterial Cpx envelope stress response.
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