期刊
TRENDS IN ENDOCRINOLOGY AND METABOLISM
卷 27, 期 9, 页码 603-605出版社
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tem.2016.03.003
关键词
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资金
- Intramural NIH HHS [ZIA DK075063-04, ZIA DK075062-04, ZIA DK075057-05] Funding Source: Medline
Bombesin-like receptor 3 (BRS-3) is an X-linked orphan. Gq-coupled receptor that regulates food intake, metabolic rate, body temperature, heart rate, blood pressure, and insulin secretion. Most BRS-3 actions occur via the brain, through mechanisms including regulating sympathetic outflow. Ablation of Brs3 causes obesity, while synthetic agonists produce weight loss.
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